Monensin inhibits recycling of macrophage mannose-glycoprotein receptors and ligand delivery to lysosomes [PDF]
, 1984 Thomas Wileman +3 more
openalex +1 more source
Advanced Intelligent Discovery, EarlyView.A novel machine learning approach classifies macrophage phenotypes with up to 98% accuracy using only nuclear morphology from DAPI‐stained images. Bypassing traditional surface markers, the method proves robust even on complex textured biomaterial surfaces. It offers a simpler, faster alternative for studying macrophage behavior in various experimental
Oleh Mezhenskyi +5 more
wiley +1 more source
AP2M1 Is a Candidate Gene for Microcephaly and Intellectual Disability in 3q27.1 Deletions
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Deletions of the 3q26.33q27.2 region appear to correlate with a distinct phenotype, although there are few reported cases. Here, we present seven previously unreported individuals carrying de novo 3q27 deletions (under 5 Mb), which include the AP2M1 (adaptor‐related protein complex 2, mu‐1 subunit) gene and summarize data from 12 previously ...
Russell Gear +16 more
wiley +1 more source
Redistribution of mannose-6-phosphate receptors induced by tunicamycin and chloroquine. [PDF]
, 1984 Wendy J. Brown +2 more
openalex +1 more source
Peptide/Antibody–Drug Conjugates for Therapeutic Applications in Inflammatory Disease
Advanced NanoBiomed Research, EarlyView.Peptide/antibody–drug conjugates (PADCs) combine ligand specificity and cleavable linkers to deliver drugs precisely to disease sites with minimal toxicity. While current approvals focus on oncology, this review examines their untapped potential in inflammatory diseases, detailing mechanisms of targeted delivery and highlighting advances that position ...
Yeongji Jang +5 more
wiley +1 more source
Human Mannose Receptor 1 Attenuates HIV-1 Infectivity in a Virus Isolate-Specific Manner. [PDF]
Viruses, 2023 Saito H, Sukegawa S, Kao S, Strebel K.
europepmc +1 more source
Accumulation of coated vesicles bearing mannose 6-phosphate receptors for lysosomal enzymes in the Golgi region of I-cell fibroblasts. [PDF]
, 1984 Wendy J. Brown, M G Farquhar
openalex +1 more source
Selective Chemical Manipulation of Mannosyl‐ and Galactosyl‐Queuosine in tRNAs of Living Cells
Angewandte Chemie International Edition, EarlyView.The Q‐base in the anticodon loop of certain eukaryotic tRNA is further mannosylated and galactosylated. Using feeding of chemically manipulated queuine derivatives, we show that the sugar‐modifying enzymes perform the modification chemistry with high regio‐ and chemoselectivity.
Alexander Pichler +7 more
wiley +1 more source
Impact of Asialoglycoprotein Receptor and Mannose Receptor Deficiency on Murine Plasma N-glycome Profiles. [PDF]
Mol Cell Proteomics, 2023 Svecla M +8 more
europepmc +1 more source
Animal Research and One Health, EarlyView.This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou +4 more
wiley +1 more source