Results 181 to 190 of about 84,098 (261)

RNF13 is a previously undescribed interactor of iduronate 2‐sulfatase that modifies its glycosylation and maturation

The FEBS Journal, EarlyView.
Iduronate 2‐sulfatase (IDS; purple) is expressed as a precursor protein that goes through multiple steps of maturation, modification, and trafficking to become an active lysosomal enzyme that degrades glycosaminoglycans. Our study shows that the transmembrane ubiquitin ligases RNF13 (orange) and RNF167 (pink) heterodimerize, affecting IDS intracellular
Valérie C. Cabana, Antoine Y. Bouchard, Audrey M. Sénécal, Laurent Cappadocia, Marc P. Lussier   +4 more
wiley   +1 more source

Macrophages exploit the mannose receptor and JAK-STAT1-MHC-II pathway to drive antigen presentation and the antimycobacterial immune response after BCG vaccination. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Zhang Y, Xu D, Nie Q, Wang J, Fang D, Xie Y, Xiong H, Pan Q, Zhang XL.   +8 more
europepmc   +1 more source

Key metabolites secreted by Chlorella vulgaris alleviate salt stress in soybean seedlings

Journal of Integrative Plant Biology, EarlyView.
Chlorella vulgaris secretes exosome‐derived linolenic acid and inosine, which alleviate salt stress and enhance salt tolerance in soybean seedlings by activating stress‐responsive signaling networks. ABSTRACT Soil salinization is a major abiotic stress factor that reduces soybean production.
Yunyi Shi, Ruitong Chen, Kai Jiang, Aijuan Jiang, Jianchao Yang, Hongli Cui, Min Chen   +6 more
wiley   +1 more source

Jasmonate Modulates Strawberry Susceptibility to Anthracnose by Activating SnRK2.1 to Regulate the WRKY50‐JAZ5 Module

Plant Biotechnology Journal, EarlyView.
ABSTRACT Colletotrichum spp., hemibiotrophic fungal pathogens, threaten global strawberry production. Jasmonate (JA) regulates plant‐Colletotrichum interactions, but its mechanisms remain unclear. Here we demonstrate that both exogenous methyl jasmonate (MeJA) treatment and elevated endogenous MeJA levels increase strawberry susceptibility to ...
Chuang Liu, Zhen Liu, Xia Li, Yating Chen, Ronghui Sun, Peijie Li, Qianqian Feng, Yuanhua Wang, Jie Ren, Qian Li, Bingbing Li   +10 more
wiley   +1 more source

CpERF‐WRI1 Manipulates Ethylene Sensing by Regulating the Expression of CpERS1 and Fruit Ripening in Papaya

Plant Biotechnology Journal, EarlyView.
ABSTRACT Ethylene plays a crucial role in fruit ripening and is perceived by specialised receptor proteins embedded in the endoplasmic reticulum (ER) membrane. As an ethylene antagonist, 1‐methylcyclopropene (1‐MCP) binds to these receptors and delays papaya ripening, but improper use can cause ripening disorders.
Ziling Wu, Jiahui Cai, Faiz Ur Rahman, Wang Zheng, Qiunan Zhu, Weixin Chen, Xueping Li, Xiaoyang Zhu   +7 more
wiley   +1 more source

Mannose receptor targeted bioadhesive chitosan nanoparticles of clofazimine for effective therapy of tuberculosis. [PDF]

Saudi Pharm J, 2020
Pawde DM, Viswanadh MK, Mehata AK, Sonkar R, Narendra, Poddar S, Burande AS, Jha A, Jha A, Vajanthri KY, Mahto SK, Azger Dustakeer VN, Muthu MS.   +12 more
europepmc   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Transcriptional regulation of the HIV-1 inhibitory factor human mannose receptor 1 by the myeloid-specific transcription factor PU.1. [PDF]

J Virol
Mallorson R, Miyagi E, Kao S, Sukegawa S, Saito H, Fabryova H, Morellatto Ruggieri L, Mediouni S, Valente ST, Strebel K.   +9 more
europepmc   +1 more source

Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies

Transfusion, EarlyView.
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike, Albert Bondt, Douwe Schulte, Rien Leuvenink, Dirk Jan Mons, Peter C. Ligthart, E. Joanne T. Verweij, AFRICARhE Consortium, Enrico Lopriore, E. J. T. Joanne Verweij, Tienke Vermeiden, Thomas van den Akker, C. Ellen van der Schoot, Derek P. de Winter, Renske van Oever, Abera Kenay Tura, Tadesse Gure, Assefa Desalew, Tewodros Tesfa, Konjit Eshetu, Jeremia Pyuza, Rafiki N. Mjema, Priscus John Mapendo, Jeremiah John Hhera, Bariki Mchome, Patricia Swai, Blandina T. Mmbaga, Aisa Shayo, Peter Moons, Kondwani Kawaza, Luis Gadama, Albert J. R. Heck, C. Ellen van der Schoot, Gestur Vidarsson   +33 more
wiley   +1 more source

The Glycan Ectodomain of SARS-CoV-2 Spike Protein Modulates Cytokine Production and Expression of CD206 Mannose Receptor in PBMC Cultures of Pre-COVID-19 Healthy Subjects. [PDF]

Viruses
Barbati C, Bromuro C, Vendetti S, Torosantucci A, Cauda R, Cassone A, Palma C.   +6 more
europepmc   +1 more source