Results 81 to 90 of about 405 (90)

TAC1b mutation in Candida auris decreases manogepix susceptibility owing to increased CDR1 expression. [PDF]

Antimicrobial Agents and Chemotherapy
Candida auris is an emerging pathogenic fungus that is highly resistant to existing antifungal drugs. Manogepix is a novel antifungal agent that exerts antifungal activity by inhibiting glycosylphosphatidylinositol anchor biosynthesis.
Masato Tashiro, Takahiro Takazono, Koichi Makimura   +2 more
exaly   +4 more sources

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Activities of Manogepix and Comparators against 1,435 Recent Fungal Isolates Collected during an International Surveillance Program (2020).

Antimicrobial Agents and Chemotherapy, 2022
Michael D Huband, Mariana Castanheira, P R Rhomberg   +2 more
exaly  

2043. In Vitro Activity of Manogepix Against 2,810 Fungal Isolates from the SENTRY Surveillance Program (2020-2021) Stratified by Infection Type

Open Forum Infectious Diseases, 2022
Michael D Huband, Mariana Castanheira
exaly  

Enhanced Efflux Pump Expression in Candida Mutants Results in Decreased Manogepix Susceptibility.

Antimicrobial Agents and Chemotherapy, 2020
Leah E Cowen, Luke Whitesell, Sean D Liston   +2 more
exaly  

In Vitro Activity of Manogepix against Multidrug-Resistant and Panresistant Candida auris from the New York Outbreak.

Antimicrobial Agents and Chemotherapy, 2020
Vishnu Chaturvedi, Sudha Chaturvedi, Karen J Shaw   +2 more
exaly  

Synthesis of analogs of the Gwt1 inhibitor manogepix (APX001A) and evaluation against spp

Bioorganic and Medicinal Chemistry Letters, 2019
Karen J Shaw, Mili Kapoor
exaly  

Evaluation of Resistance Development to the Gwt1 Inhibitor Manogepix (APX001A) in Candida Species.

Antimicrobial Agents and Chemotherapy, 2019
Karen J Shaw, Mili Kapoor
exaly  

In Vitro Activity of APX001A (Manogepix) and Comparator Agents against 1,706 Fungal Isolates Collected during an International Surveillance Program in 2017.

Antimicrobial Agents and Chemotherapy, 2019
Mariana Castanheira, R K Flamm
exaly  

In vitro activity of manogepix and comparators against infrequently encountered yeast and mold isolates from the SENTRY Surveillance Program (2017-2022).

Antimicrobial Agents and Chemotherapy
Cecilia Carvalhaes, Michael D Huband, Mariana Castanheira   +2 more
exaly  

In vitro manogepix susceptibility testing of South African Emergomyces africanus, Emergomyces pasteurianus, and Blastomyces emzantsi clinical isolates.

Antimicrobial Agents and Chemotherapy
Nelesh P Govender, Tsidiso G Maphanga, Silondiwe Nzimande   +2 more
exaly