Ibrexafungerp prolongs survival and reduces the eumycetoma grain size in Galleria mellonella infection models of two different causative agents of eumycetoma [PDF]
OBJECTIVES: Eumycetoma is a neglected tropical fungal disease of the subcutaneous tissue that is currently not treatable with medication only. Standard itraconazole therapy is combined with surgical excision of the lesion.
Eadie, Kimberly +5 more
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REGULATION OF CELLULAR STRESSES IN YEAST CELLS BY CALCINEURIN [PDF]
Calcineurin is a conserved Ca2+/calmodulin-dependent protein phosphatase. Originally identified for its abundant expression neurons, calcineurin has a well-defined role in activating T-cells and the adaptive immune response. Two inhibitors of calcineurin,
Pavesic, Matthew
core +3 more sources
Optimising the Treatment of Invasive Candidiasis – A Case for Combination Therapy [PDF]
Invasive candidiasis is a rising global health threat with increasing incidence, persistently high mortality and diminishing treatment options. Antifungal resistance has rapidly emerged and spread, with multidrug resistant species deemed an urgent and ...
Allebone-Salt, PE +9 more
core +1 more source
Nuevos tratamientos para la candidiasis oral [PDF]
, 2021 La candidiasis oral (CO) es una de las infecciones fúngicas más comunes que aparece en la cavidad oral. Su principal agente causal es la Candida, un hongo oportunista que se encuentra en la flora oral normal. Sin embargo, en ocasiones puede ocurrir un
Baloco Núñez, Sara Fernanda
core
American Society of Transplantation and Cellular Therapy Series: #8-Management and Prevention of Non-Aspergillus Molds in Hematopoietic Cell Transplantation Recipients. [PDF]
The Practice Guidelines Committee of the American Society of Transplantation and Cellular Therapy partnered with its Transplant Infectious Disease Special Interest Group to create a guideline focusing on non-Aspergillus invasive molds, which are uncommon
Carpenter, P.A. +10 more
core +1 more source
Efeito antifúngico do fosmanogepix frente a infecções causados por Candida auris: uma revisão da literatura [PDF]
Resistant microorganisms poses a challenge to the treatment of infections, limiting therapeutic drug options. Some fungal species, such as Candida auris, have shown resistance to the major classes of antifungals available.
Vitorino, Gabriel Fernando Melo
core
The Potential of Thymus zygis L. (Thyme) Essential Oil Coating in Preventing Vulvovaginal Candidiasis on Intrauterine Device (IUD) Strings [PDF]
Background/Objectives: Fungal colonization and biofilm formation on intrauterine device (IUD) strings are known to contribute to recurrent infections and decreased contraceptive efficacy.
Beksac, Mehmet Sinan +4 more
core +1 more source
Towards covalent inhibition of phosphoglucomutase in Aspergillus fumigatus [PDF]
, 2023 Kowalski, Bartosz
core +1 more source
Duration of systemic antifungal therapy for patients with invasive fungal diseases: A reassessment. [PDF]
Invasive fungal diseases are associated with significant morbidity and mortality, especially among immunocompromised patients, and often prompt for rapid and aggressive treatment aiming cure. Due to the expanding magnitude of patients burdened by chronic
Calandra, T. +5 more
core +1 more source
Autochtonous Emergomyces pasteurianus subcutaneous infection in an Italian immunocompromised patient: a case report and review [PDF]
We describe the second case of infection by Emergomyces pasteurianus that occurred in Italy. The patient presented ulcerated nodular lesions primarily in the forehead, beneath the orbital and nasal areas, but also in the neck and fingers in the early ...
Alessandra Tebaldi +6 more
core +2 more sources