Results 51 to 60 of about 381 (103)

Manogepix and amphotericin B combination is synergistic against Candida glabrata as evidenced by a new pharmacodynamic-modelling approach

Background: Candida glabrata is the second most common yeast species involved in candidemia. It presents high MICs for azoles and several strains have showed resistance or tolerance to echinocandins. Manogepix is an innovative antifungal agent that disrupts the GPI-anchor biosynthesis pathway.
Baillod, Adrien, Aranzana-Climent, Vincent, Clarhaut, Jonathan, Marchand, Sandrine, Brunet, Kevin   +4 more
openaire   +1 more source

The Upcoming Antifungal Drugs in Clinical Development for the Treatment of Invasive Candidiasis. [PDF]

Infect Drug Resist
Zubovskaia A, Vazquez JA.
europepmc   +1 more source

Assessment of the molecular identification algorithm and its impact on antifungal susceptibilities against clinical <i>Fusarium</i> isolates: a multicentre study in Taiwan, 2011-2023. [PDF]

JAC Antimicrob Resist
Chen PY, Wu CJ, Wu UI, Liu WD, Chen YC.
europepmc   +1 more source

Fusarium solani Skin and Soft Tissue Infection in a Patient With Chronic Sclerosing Skin Graft-vs-Host Disease: A Case Report. [PDF]

Am J Case Rep
Parker NJ, Quilitz R, Hussain HI, Caracciolo J, Klinkova O.   +4 more
europepmc   +1 more source

Multisystem <i>Lomentospora prolificans</i> progression on fosmanogepix despite <i>in vitro</i> activity: a call for expanding clinical research on novel antifungals. [PDF]

ASM Case Rep
Cooper RA, Arif S, Baker AW, Wiederhold NP, Sarantopoulos S, Iftikhar M, Stanly K, Collis B, Ni B, Sim BZ, Perfect JR, Alexander BD, Heldman MR.   +12 more
europepmc   +1 more source

Novel Inositol Acyltransferase (Gwt1) Inhibitor for Fungal Keratitis Treatment: Evaluation of In Vitro and In Vivo Efficacy and Safety. [PDF]

Invest Ophthalmol Vis Sci
Gowtham L, Meghana Y, Mannangatty T, Vasavi S, Nirmal J, Bagga B, Garg P, Mishra DK, Roy S.   +8 more
europepmc   +1 more source

Phase 1b safety and pharmacokinetics of intravenous and oral fosmanogepix in patients with acute myeloid leukaemia and neutropenia. [PDF]

J Antimicrob Chemother, 2023
Cornely OA, Ostermann H, Koehler P, Teschner D, Limburg E, Kramer WG, Barbat SH, Tawadrous M, Hodges MR.   +8 more
europepmc   +1 more source

GPI‑anchored protein nanoclusters license migrasome expansion and serve as exocytic platforms for migrasome. [PDF]

Nat Commun
Li X, Li Y, Xie R, Jiao H, Yu L.
europepmc   +1 more source

<i>In vitro</i> activity of novel antifungals, natamycin, and terbinafine against <i>Fusarium</i>. [PDF]

Antimicrob Agents Chemother
Garbe E, Ullah A, Aldejohann AM, Kurzai O, Janevska S, Walther G.   +5 more
europepmc   +1 more source

Successful salvage treatment of <i>Mucor nidicola</i> and <i>Aspergillus calidoustus</i> co-infection with oral encochleated amphotericin B (MAT2203) in a pediatric patient with acute myeloid leukemia. [PDF]

Med Mycol Case Rep
Ouellette CP, Ardura MI, Gibas C, Wiederhold N, Song E.   +4 more
europepmc   +1 more source