Results 61 to 70 of about 369,419 (282)

Enfoques metodológicos recientes en los manuales de historia del pensamiento económico [PDF]

open access: yes, 1989
Este documento de trabajo tan sólo realiza una posible agrupación de los distintos métodos de enfocar y abordar el estudio e investigación de la historia del pensamiento económico, al tiempo que orienta acerca de los distintos manuales que han salido al ...
Méndez Ibisate, Fernando
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

The first 50 textbooks of Aesthetics in Spain

open access: yesHistoria de la Educación, 2013
The article presents the manuals that introduced the study of aesthe - tics in Spanish classrooms. These books are designed for the student. Generally were class notes, corrected and augmented.
Ignasi ROVIRÓ ALEMANY
doaj  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Proposal for a medical emergency, diagnosis and treatment manual for intern doctors

open access: yesActa Médica del Centro, 2010
A descriptive cross-sectional study, with a qualitative approach, was carried out with the aim of proposing a manual of medical emergencies, diagnosis and treatment, used for consultation and easy to handle.
Daniel Sánchez Currás   +5 more
doaj  

Sistema Contable en la Empresa Agropecuaria ‘‘Los Potrerillos’’ S.A del municipio de Jinotega, en el I semestre del año 2015. [PDF]

open access: yes, 2016
En el presente Seminario de Graduación abordamos el Sistema Contable de las empresas de Matagalpa y Jinotega, con el fin de analizar el Sistema Contable de la Empresa Agropecuaria “Los Potrerillos S.A.” en el municipio de Jinotega en el I semestre del ...
Campos Meza, Iranel Stephan   +1 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Un manual de urbanidad para los hispanoamericanos

open access: yesKipus: Revista Andina de Letras y Estudios Culturales, 2012
Uno de los libros más leídos por los hispanoamericanos desde mediados del siglo XIX, es el Manuel de urbanidad, de Manuel Antonio Carreño. Hasta hace pocas décadas, fue texto de lectura obligatoria en la mayoría de las escuelas hispanohablantes de ...
Mirla Alcibíades
doaj  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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