Results 11 to 20 of about 7,374 (265)

Unified structural optimization method using topology optimization and genetic algorithms

open access: yesMechanical Engineering Journal, 2021
This paper presents a new structural design framework that incorporates the concept of topology optimization and genetic algorithms to improve the manufacturability and structural robustness of the optimal structure. The level set function is employed as
DoeYoung HUR   +3 more
doaj   +1 more source

Approaches to expand the conventional toolbox for discovery and selection of antibodies with drug-like physicochemical properties

open access: yesmAbs, 2023
Antibody drugs should exhibit not only high-binding affinity for their target antigens but also favorable physicochemical drug-like properties. Such drug-like biophysical properties are essential for the successful development of antibody drug products ...
Hristo L. Svilenov   +4 more
doaj   +1 more source

Advancing humanized monoclonal antibody for counteracting fentanyl toxicity towards clinical development

open access: yesHuman Vaccines & Immunotherapeutics, 2022
Innovative therapies to complement current treatments are needed to curb the growing incidence of fatal overdoses related to synthetic opioids. Murine and chimeric monoclonal antibodies (mAb) specific for fentanyl and its analogs have demonstrated pre ...
Dustin Hicks   +6 more
doaj   +1 more source

Agroecological passport of the Marusya green bean variety

open access: yesОвощи России, 2022
Relevance. As a result of long-term research, the staff of the Department of Agronomy, Plant Breeding and Seed Production of Omsk State Agrarian University created a new variety of green beans called Marusya, which was included in the State Register of ...
N. G. Kazydub   +2 more
doaj   +1 more source

Anarchic manufacturing [PDF]

open access: yesInternational Journal of Production Research, 2018
This paper introduces anarchic manufacturing, an extremely distributed planning and control philosophy, as the methodology for planning and controlling future smart factories. Anarchic manufacturing delegates decision-making authority and autonomy to the lowest level of entities in system elements with no centralised control or oversight.
Andrew Ma, Aydin Nassehi, Chris Snider
openaire   +3 more sources

A Shape Optimization Method for Part Design Derived from the Buildability Restrictions of the Directed Energy Deposition Additive Manufacturing Process

open access: yesDesigns, 2020
The design methodologies and part shape algorithms for additive manufacturing (AM) are rapidly growing fields, proven to be of critical importance for the uptake of additive manufacturing of parts with enhanced performance in all major industrial sectors.
Andreas K. Lianos   +2 more
doaj   +1 more source

Reinforced Concrete Posts Made by Long-Line Formwork-Free Shaping for 0.4–10 kV Overhead Line Supports

open access: yesНаука и техника, 2022
When using the technology of long-line formwork-free shaping for the manufacture of reinforced concrete structures, industrial engineering can be conducted in accordance with the requirements of modern regulatory documents.
P. T. Mirzaev, Z. P. Shamansurova
doaj   +1 more source

VEGETABLE PEA BREEDING ON TECHNOLOGY

open access: yesОвощи России, 2019
Breeding of high-tech varieties of vegetable peas is a priority ефыл selection at the present stage. The main requirement of processing enterprises is full and timely loading of production lines with high-quality raw materials.
I. P. Kotlyar   +3 more
doaj   +1 more source

Sustainable Manufacturability of Archimedes Screw Turbines: A Critical Review

open access: yesJournal of Manufacturing and Materials Processing, 2022
Archimedes screw turbines are considered a new technology in small- or microscale hydropower. Archimedes screw turbines are easy and practical to operate. However, their manufacturing presents some challenges owing to their screw-shaped design.
Aristotle T. Ubando   +5 more
doaj   +1 more source

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