Results 21 to 30 of about 7,374 (265)

A Laser-Engraving Technique for Portable Micropneumatic Oscillators

Micromachines, 2018
Microfluidic automation technology is at a stage where the complexity and cost of external hardware control often impose severe limitations on the size and functionality of microfluidic systems.
Vidhya Balaji, Kurt Castro, Albert Folch
doaj   +1 more source

Contact of working surfaces for spherical washers and recommendations for determining the gap in the joint [PDF]

Журнал інженерних наук, 2020
In article analyzes the technical requirements for spherical washers used in threaded connections of pumps, which made it possible to highlight contradictions in paragraphs of the current standards for pump fasteners.
Dehtiarov I. M., Neshta A. O., Samardak M. P., Antosz K., Avramenko S. E.   +4 more
doaj   +1 more source

FUZZY ASSESSMENT OF MANUFACTURABILITY DESIGN FOR MACHINING [PDF]

Applied Computer Science, 2019
The article attempts to assess the manufacturability design taking into account the assessment due to the processing, assembly process and organization of production. The evaluation was conducted by the fuzzy inference methods.
Józef MATUSZEK, Tomasz SENETA, Aleksander MOCZAŁA   +2 more
doaj   +1 more source

Industrial Additive Manufacturing: A manufacturing systems perspective [PDF]

Computers in Industry, 2017
As Additive Manufacturing becomes increasingly prevalent in commercial manufacturing environments, the need to effectively consider optimal strategies for management is increased. At present most research has focused on individual machines, yet there is a wealth of evidence to suggest competitive manufacturing is best managed from a systems perspective.
Daniel R. Eyers, Andrew T. Potter
openaire   +1 more source

Improved Manufacturability and In Vivo Comparative Pharmacokinetics of Dapagliflozin Cocrystals in Beagle Dogs and Human Volunteers

Pharmaceutics, 2021
Dapagliflozin (DAP), which improves glycemic control in patients with type 2 diabetes mellitus, has poor physical properties against heat and moisture, thus hindering its manufacturing potential.
Sangho Cho, Jeongwook Lee, Yongwon Yoo, Minyong Cho, Seil Sohn, Beom-Jin Lee   +5 more
doaj   +1 more source

The impact of repeated temperature cycling on cryopreserved human iPSC viability stems from cytochrome redox state changes

Frontiers in Bioengineering and Biotechnology
Human induced pluripotent stem cells (hiPSCs) are an attractive cell source for regenerative medicine. For its widespread use as a starting material, a robust storage and distribution system in the frozen state is necessary.
Jun Okuda, Jun Okuda, Jun Okuda, Namiko Watanabe, Namiko Watanabe, Tetsuji Nakamura, Tetsuji Nakamura, Kenta Mizushima, Heqi Xi, Yasuaki Kumamoto, Katsumasa Fujita, Masahiro Kino-Oka, Masahiro Kino-Oka   +12 more
doaj   +1 more source

Superiority of Mesoporous Silica-Based Amorphous Formulations over Spray-Dried Solid Dispersions

Pharmaceutics, 2022
The aim of this study was to compare the performance of two amorphous formulation strategies: mesoporous silica via solvent impregnation, and solid dispersions by spray drying. Poorly soluble fenofibrate was chosen as the model drug compound.
Hongwei Zhang, Minglu Li, Jianmin Li, Anjali Agrawal, Ho-Wah Hui, Demin Liu   +5 more
doaj   +1 more source

Research Progress on Bonding Wire for Microelectronic Packaging

Micromachines, 2023
Wire bonding is still the most popular chip interconnect technology in microelectronic packaging and will not be replaced by other interconnect methods for a long time in the future.
Hongliang Zhou, Yingchong Zhang, Jun Cao, Chenghao Su, Chong Li, Andong Chang, Bin An   +6 more
doaj   +1 more source

Development of disulfide-stabilized Fabs for targeting of antibody-directed nanotherapeutics

mAbs, 2022
Antibody-directed nanotherapeutics (ADNs) represent a promising delivery platform for selective delivery of an encapsulated drug payload to the site of disease that improves the therapeutic index.
Melissa L. Geddie, Dmitri B. Kirpotin, Neeraj Kohli, Tad Kornaga, Bjoern Boll, Maja Razlog, Daryl C. Drummond, Alexey A. Lugovskoy   +7 more
doaj   +1 more source

Manufacturability and functionality assessment of different formats of T-cell engaging bispecific antibodies

mAbs, 2023
T-cell-engaging bispecific antibodies (T-bsAbs) are promising immunotherapies for cancer treatment due to their capability of redirecting T-cells toward destroying tumor cells.
Han Ping Loh, Farouq Bin Mahfut, Serene W Chen, Yuhan Huang, Jianxin Huo, Wei Zhang, Kong Peng Lam, Shengli Xu, Yuansheng Yang   +8 more
doaj   +1 more source