Results 31 to 40 of about 19,710 (294)

RESEARCH ON SHIP MANUFACTURABILITY AND EVALUATION METHOD

open access: yes, 2011
Ship manufacturability is one of the most important works for modern shipbuilding industry. The basic concept of ship manufacturability and its evaluation system are discussed first. Then the characteristics of ship manufacturability are analyzed.
JIN LI, HONG YI
core   +1 more source

Knowledge-Driven Manufacturability Analysis for Additive Manufacturing

open access: yes, 2021
Additive Manufacturing (AM) evolved recently from a rapid prototyping process to a standard manufacturing tool. Nevertheless, it is still not a widely used method due to different process-related challenges.
Mayerhofer, Manuel   +5 more
core   +1 more source

Superiority of Mesoporous Silica-Based Amorphous Formulations over Spray-Dried Solid Dispersions

open access: yesPharmaceutics, 2022
The aim of this study was to compare the performance of two amorphous formulation strategies: mesoporous silica via solvent impregnation, and solid dispersions by spray drying. Poorly soluble fenofibrate was chosen as the model drug compound.
Hongwei Zhang   +5 more
doaj   +1 more source

Research Progress on Bonding Wire for Microelectronic Packaging

open access: yesMicromachines, 2023
Wire bonding is still the most popular chip interconnect technology in microelectronic packaging and will not be replaced by other interconnect methods for a long time in the future.
Hongliang Zhou   +6 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

A high-throughput platform for biophysical antibody developability assessment to enable AI/ML model training

open access: yesmAbs
Antibodies must bind their targets with high affinity and specificity to achieve useful therapeutic activity. They must also possess suitable developability properties (e.g.
Ammar Arsiwala   +27 more
doaj   +1 more source

Development of disulfide-stabilized Fabs for targeting of antibody-directed nanotherapeutics

open access: yesmAbs, 2022
Antibody-directed nanotherapeutics (ADNs) represent a promising delivery platform for selective delivery of an encapsulated drug payload to the site of disease that improves the therapeutic index.
Melissa L. Geddie   +7 more
doaj   +1 more source

Manufacturing datatypes

open access: yesJournal of Functional Programming, 2001
This article describes a general framework for designing purely functional datatypes that automatically satisfy given size or structural constraints. Using the framework we develop implementations of different matrix types (for example, square matrices) and implementations of several tree types (for example, Braun trees and 2-3 ...
openaire   +5 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Manufacturability and functionality assessment of different formats of T-cell engaging bispecific antibodies

open access: yesmAbs, 2023
T-cell-engaging bispecific antibodies (T-bsAbs) are promising immunotherapies for cancer treatment due to their capability of redirecting T-cells toward destroying tumor cells.
Han Ping Loh   +8 more
doaj   +1 more source

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