Results 61 to 70 of about 1,271,617 (289)

Non-thermal plasma technology for the development of antimicrobial surfaces: a review [PDF]

open access: yes, 2016
Antimicrobial coatings are in high demand in many fields including the biomaterials and healthcare sectors. Within recent progress in nanoscience and engineering at the nanoscale, preparation of nanocomposite films containing metal nanoparticles ( such ...
Cvelbar, U   +6 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Engineering and Environmental Analysis of Additive Manufacturing in the Food Industry

open access: yesEngineering Proceedings
In the context of increasing demands for sustainability and individualization in the food industry, additive manufacturing (AM) represents a promising technology with the potential to transform manufacturing processes.
Valentina Nikolova-Alexieva   +3 more
doaj   +1 more source

How Can We Instill a Culture of Accountability in Employees in Manufacturing Companies? [PDF]

open access: yes, 2015
For our engineering and manufacturing site, frequent leadership, ownership, and operating model changes have led to difficulty instilling a culture of ownership and accountability in employees.
Kovack, Kasey
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Selective Laser Melting: Materials and Applications

open access: yesJournal of Manufacturing and Materials Processing, 2020
Additive manufacturing (AM) is one of the emerging manufacturing techniques of immense engineering and scientific importance and is regarded as the technique of the future [...]
Konda Gokuldoss Prashanth
doaj   +1 more source

The use of simulated games in an undergraduate course manufacturing processes [PDF]

open access: yes, 2009
Simulation games bring the real engineering situation into class room. They are ideally suited to situations where the size and cost of some systems cannot be replicated in educational institutions, e.g.
Pather, Selvan, Wang, Hao
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Web-based CBR (case-based reasoning) as a tool with the application to tooling selection [PDF]

open access: yes, 2005
Over the past few years, manufacturing companies have had to deal with an increasing demand for feature-rich products at low costs. The pressures exerted on their existing manufacturing processes have lead manufacturers to investigate internet-based ...
Aamodt   +8 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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