Results 61 to 70 of about 1,209,744 (339)

Effect of advanced manufacturing technology, concurrent engineering of product design, and supply chain performance of manufacturing companies [PDF]

, 2015
As competition shifts away between competitors to supply chains, simultaneous sharing of technical expertise on product design is key to manufacturing success.
Abd Rahman, Azmawani, Ng, Siew Imm, Singhry, Hassan Barau   +2 more
core   +3 more sources

Engineering and Environmental Analysis of Additive Manufacturing in the Food Industry

Engineering Proceedings
In the context of increasing demands for sustainability and individualization in the food industry, additive manufacturing (AM) represents a promising technology with the potential to transform manufacturing processes.
Valentina Nikolova-Alexieva, Katina Valeva, Margarita Terziyska, Hristian Panayotov   +3 more
doaj   +1 more source

From Discovery to Mass Production: A Perspective on Bio-Manufacturing Exemplified by the Development of Statins

Engineering, 2023
The increasingly complex molecular structures and high requirements of advanced industries are triggering a transformation in chemical production modes. Bio-manufacturing provides efficient strategies and brings the advantages of high atomic economy, few
Xiao-Ling Tang, Jia-Wei Yu, Yu-Heng Geng, Jia-Rui Wang, Ren-Chao Zheng, Yu-Guo Zheng   +5 more
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

How Can We Instill a Culture of Accountability in Employees in Manufacturing Companies? [PDF]

, 2015
For our engineering and manufacturing site, frequent leadership, ownership, and operating model changes have led to difficulty instilling a culture of ownership and accountability in employees.
Kovack, Kasey
core   +1 more source

Data-driven engineering framework with AI algorithm of Ginkgo Folium tablets manufacturing

Acta Pharmaceutica Sinica B, 2023
Smart manufacturing still remains critical challenges for pharmaceutical manufacturing. Here, an original data-driven engineering framework was proposed to tackle the challenges.
Lijuan Ma, Jing Zhang, Ling Lin, Tuanjie Wang, Chaofu Ma, Xiaomeng Wang, Mingshuang Li, Yanjiang Qiao, Yongxiang Wang, Guimin Zhang, Zhisheng Wu   +10 more
doaj   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Synthetic biology—putting engineering into biology [PDF]

, 2006
Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we ...
Heinemann, Matthias,, Panke, Sven,
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Systematic innovation and the underlying principles behind TRIZ and TOC [PDF]

, 2003
Innovative developments in the design of product and manufacturing systems are often marked by simplicity, at least in retrospect, that has previously been shrouded by restrictive mental models or limited knowledge transfer. These innovative developments
D. Mann, Duguay, R. Stratton, Silveira, Steyn, Warburton   +5 more
core   +2 more sources