MAP kinase 1 (MAPK1; ERK-2); MAPK3 (ERK-1); MAP kinase kinase 1 (MAP2K1; MEK1) [PDF]
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Kroonisissa tulehdussairauksissa, kuten nivelreumassa, astmassa, keuhkoahtaumataudissa ja psoriaasiksessa on tyypillistä liian voimakas ja pitkittynyt tulehdusvaste, joka voi johtaa kudoksen heikentyneeseen toimintaan ja vaurioihin, aiheuttaa kipua, heikentää toimintakykyä ja lisätä riskiä sairastua liitännäissairauksiin.
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Superoxide dismutase 1 (SOD1); MAP kinase ERK-1; MAP kinase ERK-2 [PDF]
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MAP kinase kinase 1 (MAP2K1; MEK1); MAP2K2 (MEK2) [PDF]
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Mitogen-Activated Protein (MAP) Kinases Are Involved in Interleukin-1 (IL-1)-Induced IL-6 Synthesis in Osteoblasts: Modulation Not of p38 MAP Kinase, But of p42/p44 MAP Kinase by IL-1-Activated Protein Kinase C1 [PDF]
Masaichi Miwa +3 more
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Cucurbitacin B Promotes Tumor Necrosis Factor Receptor 1 Ectodomain Shedding by Selectively Activating the Extracellular Signal-Regulated Kinase Signaling Pathway. [PDF]
Yarangsee P +6 more
europepmc +1 more source
Contact-Network Phenotyping of the CDK Family Reveals Selective Distal C-Lobe Contact Redistribution by Modern CDK5 Inhibitors and a Quantitative Selectivity Landscape against CDK2 and CDK1. [PDF]
Nael MA, Alakonda LM, Elokely KM.
europepmc +1 more source
Investigation of potential targets and mechanisms of naringenin in the treatment of spinal cord injury: A network pharmacology, molecular docking, and molecular dynamics simulation study. [PDF]
Li AB, Sheng WB.
europepmc +1 more source
MAP kinase 3 (MAPK3; ERK-1); MAPK1 (ERK-2); MAP kinase kinase 1 (MAP2K1; MEK1); MAP2K2 (MEK2); c-jun N-terminal kinase 1 (JNK1; MAPK8) [PDF]
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The transcription factor Rlm1 couples the MAPK Slt2/ERK1 pathway to the IRE1-driven unfolded protein response. [PDF]
Chakraborty A +13 more
europepmc +1 more source

