Contact-Network Phenotyping of the CDK Family Reveals Selective Distal C-Lobe Contact Redistribution by Modern CDK5 Inhibitors and a Quantitative Selectivity Landscape against CDK2 and CDK1. [PDF]
J Chem Inf ModelNael MA, Alakonda LM, Elokely KM.
europepmc +1 more source
The transcription factor Rlm1 couples the MAPK Slt2/ERK1 pathway to the IRE1-driven unfolded protein response. [PDF]
Commun BiolChakraborty A +13 more
europepmc +1 more source
Structural and biochemical basis of ROC-dependent activation of LRRK2. [PDF]
PNAS NexusPark Y +7 more
europepmc +1 more source
Spatial biology of crowded tumor cells: A new map for designing drug combinations. [PDF]
Curr Opin Struct BiolNussinov R, Jang H.
europepmc +1 more source
Transcriptional derepression of negative regulators of MAP kinase supports maintenance of diapause ES cells in the pluripotent state. [PDF]
Genes DevZhang T +4 more
europepmc +1 more source
Computational Discovery and Optimization of a Potent, Selective, and Drug-Like Scaffold for p38α Inhibition. [PDF]
Drug Des Devel TherNelen J +6 more
europepmc +1 more source
Exploring the Role of the MAPK Signalling Pathway in Dog Immunity: From Cancer to Parasitic Diseases. [PDF]
Parasite ImmunolRibeiro FN, Morgado FN, Porrozzi R.
europepmc +1 more source
Let the peptides shine: SOX (Sulfonamido-OXine)-labelled peptides for direct kinase and phosphatase monitoring. [PDF]
RSC Chem BiolPapagora LE, Cochrane SA.
europepmc +1 more source
Active zone plasticity couples sleep need to presynaptic hypophosphorylation. [PDF]
Proc Natl Acad Sci U S APiao C +5 more
europepmc +1 more source