Results 231 to 240 of about 1,043,830 (367)

Colchicine Concentrations and Relationship With Colchicine Efficacy and Adverse Events: Post Hoc Analysis of a Randomized Clinical Trial of Colchicine for Gout Flare Prophylaxis

open access: yesArthritis Care &Research, EarlyView.
Objective Our objective was to examine the relationship between colchicine plasma concentrations and clinical and demographic factors and to determine the relationship between colchicine concentrations and colchicine efficacy and colchicine‐specific adverse events.
Lisa K. Stamp   +8 more
wiley   +1 more source

CO<sub>2</sub> signalling in plants. [PDF]

open access: yesPhilos Trans R Soc Lond B Biol Sci
Foyer C, Wang A, Shi K.
europepmc   +1 more source

Activation of MAP kinases and phosphorylation of caldesmon in canine colonic smooth muscle.

open access: green, 1996
William T. Gerthoffer   +7 more
openalex   +2 more sources

Gastrointestinal Perforation as a Safety Concern Among Patients With Rheumatoid Arthritis Receiving JAK Inhibitor Therapy: A Systematic Review and Network Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Gastrointestinal perforation (GIP) is a rare and life‐threatening safety concern associated with JAK inhibitors (JAKi). We aimed to review the evidence regarding the risk of GIP associated with the use of JAKi in patients with rheumatoid arthritis (RA) using a systematic review and network meta‐analysis approach.
Thipsukhon Sathapanasiri   +7 more
wiley   +1 more source

Proteomic surveys of the mouse heart unveil cardiovascular responses to nitric oxide/cGMP signaling deficiencies. [PDF]

open access: yesCommun Biol
Mohanty I   +12 more
europepmc   +1 more source

TGF-β1 activates MAP kinase in human mesangial cells: A possible role in collagen expression [PDF]

open access: bronze, 1999
Tomoko Hayashida   +3 more
openalex   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

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