Results 241 to 250 of about 1,043,830 (367)

Medicinal Chemistry Strategies in Targeting TGF-βR1 Kinase Domain: Unveiling Insights into Inhibitor Structure-Activity Relationship (SAR). [PDF]

Pharmaceuticals (Basel)
Babiker NA, Nadeem S, Abu Kariem H, Abdul Hameed A, Negmeldin AT, El-Labbad EM.   +5 more
europepmc   +1 more source

p42/44 MAP Kinase-dependent and -independent Signaling Pathways Regulate Caveolin-1 Gene Expression [PDF]

, 1999
Jeffrey A. Engelman, Xiao Lan Zhang, Babak Razani, Richard G. Pestell, Michael P. Lisanti   +4 more
openalex   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Stimulus-Transcription Coupling of TRPM3 Channels: A Signaling Pathway from the Plasma Membrane to the Nucleus. [PDF]

Biomolecules
Thiel G, Rössler OG.
europepmc   +1 more source

The Raf/MAP Kinase Cascade in Cell Cycle Regulation and Differentiation in Drosophila.

, 1996
Yasuyoshi Nishida, Yoshihiro Inoué, Leo Tsuda, Takashi Adachi‐Yamada, Young‐Mi Lim, Mami Hata, He-Yong Ha, Shin Sugiyama   +7 more
openalex   +2 more sources

Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway. [PDF]

, 1996
Carol Beadling, J. Ng, J. W. Babbage, Doreen A. Cantrell   +3 more
openalex   +1 more source

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

Interaction of <i>Serratia proteamaculans</i> with Integrins Activates Invasion-Promoting Signaling Pathways. [PDF]

Int J Mol Sci
Tsaplina O.
europepmc   +1 more source

Newly synthesized protein(s) must associate with p34cdc2 to activate MAP kinase and MPF during progesterone-induced maturation of Xenopus oocytes. [PDF]

, 1995
Ángel R. Nebreda, Julian Gannon, Tim Hunt   +2 more
openalex   +1 more source

Murine Models and Human Cell Line Models to Study Altered Dynamics of Ovarian Follicles in Polycystic Ovary Syndrome

Advanced Biology, EarlyView.
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua, Cristiano Giuliani, Giovanna Di Emidio, Samuel H Myers, Vittorio Unfer, Carla Tatone   +5 more
wiley   +1 more source