Results 261 to 270 of about 222,900 (341)

Investigating the Roles of MAPKs as Precision Oncology Targets: A Multi-cancer Expression and Survival Study. [PDF]

Cancer Genomics Proteomics
Sulaimani MN, Singh P, Saeed MU, Zaidi S, Hussain A, Alajmi MF, Shamsi A, Dohare R, Hassan MI.   +8 more
europepmc   +1 more source

A chemical-genetic approach to elucidate protein kinase function in planta [PDF]

, 2007
Böhmer, M., Romeis, T.
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

OmicIntegrator: A Simple and Versatile Tool for Meta-Analysis. [PDF]

Plants (Basel)
Gitman IFB, Grossi CEM, Arico DS, Mazzella MA, Ulloa RM.   +4 more
europepmc   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

Kinome analysis of Madurella mycetomatis identified kinases in the cell wall integrity pathway as novel potential therapeutic drug targets in eumycetoma caused by Madurella mycetomatis. [PDF]

PLoS Negl Trop Dis
Konings M, Strepis N, Manabe RI, Hasegawa A, Chaudhari S, du Pré S, Schippers M, Tagami M, Ma J, Okazaki Y, Todd M, Biersack B, Masand V, Verbon A, Kasukawa T, Abugessaisa I, van de Sande WWJ.   +16 more
europepmc   +1 more source

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source

All three MAP kinases of the MAK-1 kinase cascade localize at the contact site of fusing germlings.

Stephanie Herzog (22411247), Tanja N. Sedlacek (22411250), Kristian D. R. Roth (22411253), Manuel Reuning (22411256), Ulrike Brandt (485805), André Fleißner (4277203)   +5 more
openalex   +1 more source

Interleukin-1 activates p54 mitogen-activated protein (MAP) kinase/stress-activated protein kinase by a pathway that is independent of p21ras, Raf-1, and MAP kinase kinase.

, 1994
Timothy A. Bird, John Kyriakis, L Tyshler, Margit Gayle, A. A. Milne, G. Duke Virca   +5 more
openalex   +1 more source

Interplay Between Key Molecular Signaling Pathways and Immune Players Following Brain Irradiation. [PDF]

Mediators Inflamm
Richard SA.
europepmc   +1 more source