Results 11 to 20 of about 1,192,359 (196)
Heregulin β-1 Induces Loss of Cell-Cell Contact and Enhances Expression of MUC1 at the Cell Surface in HCC2998 and MKN45-1 Cells [PDF]
PLoS ONE, 2011 Signal transduction and cell responses after stimulation with heregulin β-1 (HRG) are examined in HCC2998 and MKN45-1 cells, which have been used for a model system to study the formation of signet ring carcinomas, one of poorly differentiated ...
Fukui, Yasuhisa +3 more
core +5 more sources
Incorporating expression data in metabolic modeling: a case study of lactate dehydrogenase [PDF]
J Theor Biol 240: 464-474 (2006), 2005 Integrating biological information from different sources to understand cellular processes is an important problem in systems biology. We use data from mRNA expression arrays and chemical kinetics to formulate a metabolic model relevant to K562 ...
Akesson +47 more
core +2 more sources
Dynamic Studies of Scaffold-dependent Mating Pathway in Yeast [PDF]
, 2006 The mating pathway in \emph{Saccharomyces cerevisiae} is one of the best understood signal transduction pathways in eukaryotes. It transmits the mating signal from plasma membrane into the nucleus through the G-protein coupled receptor and the mitogen ...
Ouyang, Qi +4 more
core +4 more sources
Neobavaisoflavone ameliorates LPS-induced RAW264.7 cell inflammations by suppressing the activation of NF-κB and MAPKs signaling pathways [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): Neobavaisoflavone (NBIF) is an isoflavone isolated from Psoralea corylifolia L. It can effectively regulate the redox state as a natural anti-oxidant and show some anti-inflammatory activity.
Qing Yuan +8 more
doaj +1 more source
Nimodipine promotes neurite outgrowth and protects against neurotoxicity in PC12 cells [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Nimodipine is an L-type voltage-dependent calcium channel (VDCC) antagonist. However, the actions of nimodipine except calcium blocking are poorly understood. This study aimed to investigate the effect of nimodipine on neurite outgrowth and
Miduki Kusakabe, Yasushi Hasegawa
doaj +1 more source
Journal of Fungi, 2022 Morphogenesis is a strictly regulated efficient system in eukaryotes for adapting to environmental changes. However, the morphogenesis regulatory mechanism in smut fungi is not clear.
Enping Cai +7 more
doaj +1 more source
Acta Cirúrgica Brasileira, 2022 Purpose: The active melanocytes in the skin were affected by hormones and ultraviolet (UV) irradiation. Licorice zinc has a whitening effect, which may have a prominent potential in the treatment of pigmented skin disease.
Jing-yan Wang +6 more
doaj +1 more source
Scientific Reports, 2022 Coordinating the balance between development and stress responses is critical for organismal survival. However, the cellular signaling controlling this mechanism is not well understood.
Rose Aria Malinow +3 more
doaj +1 more source
Resolving the binding-kinase discrepancy in bacterial chemotaxis: A nonequilibrium allosteric model and the role of energy dissipation [PDF]
Proc. Natl. Acad. Sci. U.S.A. 120, e2303115120 (2023), 2023 The Escherichia coli chemotaxis signaling pathway has served as a model system for studying the adaptive sensing of environmental signals by large protein complexes. The chemoreceptors control the kinase activity of CheA in response to the extracellular ligand concentration and adapt across a wide concentration range by undergoing methylation and ...
arxiv +1 more source