Results 141 to 150 of about 495,928 (201)

Revisiting the role of MAPK signalling pathway in plants and its manipulation for crop improvement

Plant, Cell and Environment, 2023
The mitogen-activated protein kinase (MAPK) pathway is an important signalling event associated with every aspect of plant growth, development, yield, abiotic and biotic stress adaptation.
Alok Sinha
exaly   +2 more sources

ERK/MAPK signalling in the developing brain: Perturbations and consequences

Neuroscience and Biobehavioral Reviews, 2021
The extracellular regulated kinase/microtubule-associated protein kinase (ERK/MAPK) signalling pathway transduces signals that cause an alteration in the ongoing metabolic pathways and modifies gene expression patterns; thus, influencing cellular ...
Omamuyovwi Ijomone, Omowumi Femi-Akinlosotu, Olayemi Ijomone   +2 more
exaly   +2 more sources

The MAPK signaling cascade

The FASEB Journal, 1995
The transmission of extracellular signals into their intracellular targets is mediated by a network of interacting proteins that regulate a large number of cellular processes. Cumulative efforts from many laboratories over the past decade have allowed the elucidation of one such signaling mechanism, which involves activations of ...
R. Seger, E. Krebs
semanticscholar   +3 more sources

E3 ligases and deubiquitinating enzymes regulating the MAPK signaling pathway in cancers.

Biochimica et biophysica acta. Reviews on cancer, 2022
The mitogen-activated protein kinase (MAPK) signaling pathway is the primary regulatory module of various cellular processes such as cell proliferation, differentiation, and stress responses.
Hong-Beom Park, K. Baek
semanticscholar   +1 more source

Interplay between MAPK/ERK signaling pathway and MicroRNAs: A crucial mechanism regulating cancer cell metabolism and tumor progression.

Life Science, 2021
Mitogen-activated protein kinase (MAPK) signal transduction, as a highly conserved signaling pathway, is reported to be involved in various biological events including metabolic reprogramming, cell proliferation, survival, and differentiation.
E. Asl, M. Amini, S. Najafi, B. Mansoori, A. Mokhtarzadeh, A. Mohammadi, Parisa Lotfinejad, M. Bagheri, Solmaz Shirjang, Ziba Lotfi, Yousef Rasmi, B. Baradaran   +11 more
semanticscholar   +1 more source

Rice MAPKs

Biochemical and Biophysical Research Communications, 2003
Mitogen-activated protein kinase (MAPK) cascades are evolutionary conserved from unicellular to complex eukaryotic organisms, and constitute one of the major signalling pathways involved in regulating a wide range of cellular activities from growth and development to cell death.
Ganesh K, Agrawal, Hitoshi, Iwahashi, Randeep, Rakwal   +2 more
openaire   +2 more sources

Exposure to polystyrene microplastics causes reproductive toxicity through oxidative stress and activation of the p38 MAPK signaling pathway.

Ecotoxicology and Environmental Safety, 2019
Microplastics (MP) are receiving increased attention as a harmful environmental pollutant, however information on the reproduction toxicity of MP in terrestrial animals, especially mammals, is limited.
Xiaoman Xie, Ting Deng, Jiufei Duan, Jing Xie, Jun-lin Yuan, Mingqing Chen   +5 more
semanticscholar   +1 more source

RAS/MAPK signaling functions in oxidative stress, DNA damage response and cancer progression

Journal of Cellular Physiology, 2019
Mitogen‐activated protein kinase (MAPK) signaling pathways organize a great constitution network that regulates several physiological processes, like cell growth, differentiation, and apoptotic cell death.
Setareh Rezatabar, Ansar Karimian, V. Rameshknia, H. Parsian, M. Majidinia, Tayebeh Azramezani Kopi, A. Bishayee, A. Sadeghinia, M. Yousefi, Mohsen Monirialamdari, B. Yousefi   +10 more
semanticscholar   +1 more source

Multisite phosphorylation by MAPK

Science, 2016
Progressive phosphorylation controls the activity of a transcription ...
Whitmarsh, Alan J., Davis, Roger J.
openaire   +3 more sources