Clinical use of CCR5 inhibitors in HIV and beyond
Since the discovery of CCR5 as a coreceptor for HIV entry, there has been interest in blockade of the receptor for treatment and prevention of HIV infection.
Gilliam Bruce +2 more
doaj
CCR5 blockade inhibits menstrual-driven proinflammatory T cell infiltration into the cervicovaginal mucosa of women. [PDF]
Swaims-Kohlmeier A +7 more
europepmc +1 more source
T cell-derived CCL5 drives macrophage immunometabolic remodeling in chronic prostatitis via the CCR5-ERK-PKM2/HIF-1α axis. [PDF]
Liu X +11 more
europepmc +1 more source
Maraviroc for Stroke Recovery (MASTER): protocol for a phase 2 double-blind placebo-controlled randomised clinical trial. [PDF]
Broc N +3 more
europepmc +1 more source
Donor macrophage depletion permits posttransplant tolerance induction in a murine islet transplant model. [PDF]
Dilts M, Fay OK, Yu Y, Jordan CZ, Luo X.
europepmc +1 more source
CCL5 improves radiation resistance through activation of the AMPK/mTOR pathway in adenoid cystic carcinoma. [PDF]
Tan M, Chen Y, Yang J, Wang Q, Li L.
europepmc +1 more source
Subgroup analyses of Maraviroc in previously treated R5 HIV-1 infection
Background We conducted subanalyses of the combined results of the Maraviroc versus Optimized Therapy in Viremic Antiretroviral Treatment- Experienced Patients (MOTIVATE) 1 and MOTIVATE 2 studies to better characterize the efficacy and safety of ...
Raffi, F +20 more
core
Tumor-educated macrophages promote cytokine-driven lung colonization in triple-negative breast cancer. [PDF]
Rosado-Sanz M +13 more
europepmc +1 more source
Harnessing lipid-driven immunometabolic pathways in omental metastases to enhance immunotherapy in patients with ovarian cancer. [PDF]
Suarez-Carmona M +38 more
europepmc +1 more source
Selected Chemokines as Prognostic Biomarkers and Therapeutic Targets in Ovarian Cancer. [PDF]
Długaszek A +7 more
europepmc +1 more source

