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Can Marburg virus be sexually transmitted? [PDF]

Health Science Reports
Background and Aim Marburg virus (MARV) is a highly virulent virus of animal origin and the cause of a lethal infection (known as Marburg virus disease [MVD]) with a case‐fatality ratio ranging from 24% to 90%.
Hassan Karami, Arash Letafati, Somayeh Sadat Hosseini Fakhr   +2 more
doaj   +5 more sources

Micro‒Global Positioning Systems for Identifying Nightly Opportunities for Marburg Virus Spillover to Humans by Egyptian Rousette Bats

Emerging Infectious Diseases, 2023
Marburg virus disease, caused by Marburg and Ravn orthomarburgviruses, emerges sporadically in sub-Saharan Africa and is often fatal in humans. The natural reservoir is the Egyptian rousette bat (ERB), which sheds virus in saliva, urine, and feces ...
Brian R. Amman, Amy J. Schuh, Gloria Akurut, Kilama Kamugisha, Dianah Namanya, Tara K. Sealy, James C. Graziano, Eric Enyel, Emily A. Wright, Stephen Balinandi, Julius J. Lutwama, Rebekah C. Kading, Patrick Atimnedi, Jonathan S. Towner   +13 more
doaj   +2 more sources

Cheminformatics Strategies Unlock Marburg Virus VP35 Inhibitors from Natural Compound Library

Viruses, 2023
The Ebola virus and its close relative, the Marburg virus, both belong to the family Filoviridae and are highly hazardous and contagious viruses. With a mortality rate ranging from 23% to 90%, depending on the specific outbreak, the development of ...
Isra M. Alsaady, Leena H. Bajrai, Thamir A. Alandijany, Hattan S. Gattan, Mai M. El-Daly, Sarah A. Altwaim, Rahaf T. Alqawas, Vivek Dhar Dwivedi, Esam I. Azhar   +8 more
doaj   +2 more sources

Modified coptisine derivatives as an inhibitor against pathogenic Rhizomucor miehei, Mycolicibacterium smegmatis (Black Fungus), Monkeypox, and Marburg virus by molecular docking and molecular dynamics simulation-based drug design approach

Frontiers in Pharmacology, 2023
During the second phase of SARS-CoV-2, an unknown fungal infection, identified as black fungus, was transmitted to numerous people among the hospitalized COVID-19 patients and increased the death rate.
Shopnil Akash, Arafat Hossain, Nobendu Mukerjee, Nobendu Mukerjee, Md. Moklesur Rahman Sarker, Md. Moklesur Rahman Sarker, Mohammad Firoz Khan, Md. Jamal Hossain, Mohammad A. Rashid, Ajoy Kumer, Arabinda Ghosh, Darwin A. León-Figueroa, Joshuan J. Barboza, Bijaya Kumar Padhi, Ranjit Sah, Ranjit Sah, Ranjit Sah   +16 more
doaj   +2 more sources

The Current Pathogenicity and Potential Risk Evaluation of Marburg Virus to Cause Mysterious “Disease X”—An Update on Recent Evidences

Environmental Health Insights
The World Health Organization (WHO) defined Disease X as an upcoming disease with the potential to cause a pandemic. Pathogen X is responsible for Disease X.
Rahima Akter Mitu, Md. Rabiul Islam
doaj   +2 more sources

Seasonal pulses of Marburg virus circulation in juvenile Rousettus aegyptiacus bats coincide with periods of increased risk of human infection. [PDF]

PLoS Pathogens, 2012
Marburg virus (family Filoviridae) causes sporadic outbreaks of severe hemorrhagic disease in sub-Saharan Africa. Bats have been implicated as likely natural reservoir hosts based most recently on an investigation of cases among miners infected in 2007 ...
Brian R Amman, Serena A Carroll, Zachary D Reed, Tara K Sealy, Stephen Balinandi, Robert Swanepoel, Alan Kemp, Bobbie Rae Erickson, James A Comer, Shelley Campbell, Deborah L Cannon, Marina L Khristova, Patrick Atimnedi, Christopher D Paddock, Rebekah J Kent Crockett, Timothy D Flietstra, Kelly L Warfield, Robert Unfer, Edward Katongole-Mbidde, Robert Downing, Jordan W Tappero, Sherif R Zaki, Pierre E Rollin, Thomas G Ksiazek, Stuart T Nichol, Jonathan S Towner   +25 more
doaj   +3 more sources

A mathematical model of Marburg virus disease outbreaks and the potential role of vaccination in control

BMC Medicine, 2023
Background Marburg virus disease is an acute haemorrhagic fever caused by Marburg virus. Marburg virus is zoonotic, maintained in nature in Egyptian fruit bats, with occasional spillover infections into humans and nonhuman primates.
George Y. Qian, W. John Edmunds, Daniel G. Bausch, Thibaut Jombart   +3 more
doaj   +2 more sources

How severe and prevalent are Ebola and Marburg viruses? A systematic review and meta-analysis of the case fatality rates and seroprevalence [PDF]

BMC Infectious Diseases, 2016
Background Ebola and Marburg virus diseases are said to occur at a low prevalence, but are very severe diseases with high lethalities. The fatality rates reported in different outbreaks ranged from 24–100%.
Luke Nyakarahuka, Clovice Kankya, Randi Krontveit, Benjamin Mayer, Frank N. Mwiine, Julius Lutwama, Eystein Skjerve   +6 more
doaj   +2 more sources

Update on the Phylodynamic and Genetic Variability of Marburg Virus

Viruses, 2023
The COVID-19 pandemic has not only strained healthcare systems in Africa but has also intensified the impact of emerging and re-emerging diseases. Specifically in Equatorial Guinea, mirroring the situation in other African countries, unique zoonotic ...
Fabio Scarpa, Liliana Bazzani, Marta Giovanetti, Alessandra Ciccozzi, Francesca Benedetti, Davide Zella, Daria Sanna, Marco Casu, Alessandra Borsetti, Eleonora Cella, Stefano Pascarella, Antonello Maruotti, Massimo Ciccozzi   +12 more
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A retrospective cohort investigation of seroprevalence of Marburg virus and ebolaviruses in two different ecological zones in Uganda [PDF]

BMC Infectious Diseases, 2020
Background Uganda has experienced seven Ebola Virus Disease (EVD) outbreaks and four Marburg Virus Disease (MVD) outbreaks between 2000 and 2019. We investigated the seroprevalence and risk factors for Marburg virus and ebolaviruses in gold mining ...
Luke Nyakarahuka, Ilana J. Schafer, Stephen Balinandi, Sophia Mulei, Alex Tumusiime, Jackson Kyondo, Barbara Knust, Julius Lutwama, Pierre Rollin, Stuart Nichol, Trevor Shoemaker   +10 more
doaj   +2 more sources