Results 111 to 120 of about 1,701,603 (284)

Emergence of Marburg Virus Disease in West Africa amid COVID-19 and Ebola: Efforts, Challenges, and Recommendations to Prevent the Next Public Health Crisis

Journal of Infectious Diseases and Epidemiology, 2022
Marburg virus disease (MVD) is a type of hemorrhagic fever caused by a genetically unique animal-borne RNA virus of the filovirus family-like Ebola virus. The African fruit bat is the known reservoir of this virus, and due to its animal-to-animal, animal-
Lawrence Jannel A, Rasool Muhammad Haseeb ul, Parikh Charmy, Chowdhury Selia, Sueldo Alexandra, Sarwar Sarosh, Mago Arpit, Thada Pawan Kumar, Skeikh Mona   +8 more
semanticscholar   +1 more source

Diverse hosts, diverse immune systems: Evolutionary variation in bat immunology

Annals of the New York Academy of Sciences, EarlyView.
Bats are recognized to have distinct immune systems from other vertebrates that may allow them to host virulent pathogens without showing disease. However, these flying mammals are also incredibly diverse, such that bats should not be expected to be immunologically homogenous.
Daniel J. Becker, Amanda Vicente‐Santos, Ashley B. Reers, B. R. Ansil, Mika O'Shea, Caroline A. Cummings, Alicia J. Roistacher, Rita M. Quintela‐Tizon, Manuela M. T. Pereira, Juniper Rosen, Arinjay Banerjee, Hannah K. Frank   +11 more
wiley   +1 more source

Designing of a Multi-epitope Vaccine against the Structural Proteins of Marburg Virus Exploiting the Immunoinformatics Approach

ACS Omega, 2021
Marburg virus disease (MVD) caused by the Marburg virus (MARV) generally appears with flu-like symptoms and leads to severe hemorrhagic fever. It spreads via direct contact with infected individuals or animals.
S. Sami, Kay Kay Shain Marma, S. Mahmud, Md. Asif Nadim Khan, Sarah M. Albogami, A. El-Shehawi, A. Rakib, A. Chakraborty, Mostafah Mohiuddin, K. Dhama, M. Uddin, M. K. Hossain, T. Tallei, T. Emran   +13 more
semanticscholar   +1 more source

Interactions of Marburg Virus Nucleocapsid Proteins

Virology, 1998
In this study, the components of Marburg virus nucleocapsid complex were determined, and interactions between the compounds were investigated. Using salt dissociation of isolated virions, four proteins (NP, VP35, VP30, and L) remained attached to the core complex.
Rinne C, Hofsäss U, Hans-Dieter Klenk, Elke Mühlberger, Stephan Becker   +4 more
openaire   +3 more sources

In silico exploration of deep-sea fungal metabolites as inhibitor of Ebola and Marburg VP35 and VP40.

PLoS ONE
VP30 and VP40 proteins of Ebola and Marburg viruses have been recognized as potential targets for antiviral drug development due to their essential roles in the viral lifecycle.
Abdullah R Alanzi, Mohammed F Alajmi, Mohammed S Al-Dosari, Mohammad K Parvez, Moneerah J Alqahtani   +4 more
doaj   +1 more source

Health services for survivors of gender-based violence in northern Uganda: a qualitative study.

, 2008
The 20-year war in northern Uganda has resulted in up to 1.7 million people being internally displaced, and impoverishment and vulnerability to violence amongst the civilian population.
Borchert, Matthias, Henttonen, Mirkka, Kaducu, Felix, Roberts, Bayard, Watts, Charlotte   +4 more
core   +1 more source

Survival Outcomes and Impact of Targeted PAH Therapy in Portopulmonary Hypertension in the PVRI GoDeep Meta‐Registry

Pulmonary Circulation, Volume 15, Issue 3, July 2025.
ABSTRACT Portopulmonary hypertension (PoPH), a type of pulmonary arterial hypertension (PAH) in patients with liver disease, is associated with high morbidity and mortality. The relationship between cardiopulmonary hemodynamics, PAH therapy, and survival in PoPH remains unclear.
Arun Jose, Athiththan Yogeswaran, Meike Fuenderich, David Kiely, Andrew J. Sweatt, Roham T. Zamanian, Paul M. Hassoun, Antoine Mouawad, Aparna Balasubramanian, Martin Wilkins, Allan Lawrie, Luke Howard, Sandeep Sahay, Horst Olschewski, Gabor Kovacs, Khaled Saleh, Hani Sabbour, Christina A. Eichstaedt, Ekkehard Grünig, George Giannakoulas, Alexandra Arvanitaki, Yuriy Sirenko, Olena Torbas, Hector Cajigas, Robert Frantz, Laura Scelsi, Stefano Ghio, Raphael W. Majeed, Jochen Wilhelm, Hossein Ardeschir Ghofrani, Friedrich Grimminger, Khodr Tello, Jean Elwing, Werner Seeger, the PVRI‐GoDeep‐Consortium, Imad Al Ghouleh, Jeffrey S. Annis, Anastasia Anthi, Tobiah Antoine, Evan Brittain, John Cannon, Stephen Y. Chan, Victoria Damonte, Efrosyui Dima, Diego Echazarreta, Kai Förster, Marlize Frauendorf, Anne Hilgendorff, Ernesto Junaeda, Ingrid King, Ziad Konswa, Philipp Krieb, Kurt Marquardt, Hiromi Matsubara, Karen Osborn, Joanna Pepke‐Zaba, Stephan Rosenkranz, Thenappan Thenappan, Ioan Tilea, Andrea Varga, Hellen M. Whitford, Paul G. Williams, Zhenguo Zhei   +62 more
wiley   +1 more source

Treponema pallidum Protein Tp0136 Induces Spheroidization of Vascular Endothelial Cells, Resulting in Widened Intercellular Junctions and Enhanced Vascular Permeability

Small Science, Volume 5, Issue 7, July 2025.
Treponema pallidum protein Tp0136 enhances vascular permeability by upregulating CSRP1, which induces MYO10 exon 19 skipping, reducing MYO10 expression and triggering endothelial spheroidization. This study reveals a novel RNA splicing‐mediated dissemination mechanism, proposing CSRP1/MYO10 as therapeutic targets to limit bacterial dissemination in ...
Yu Lin, Xi Luo, Xu Shen, Xiao‐Lin Fu, Li‐Rong Lin, Tian‐Ci Yang   +5 more
wiley   +1 more source

Wave-like spread of Ebola Zaire [PDF]

, 2005
In the past decade the Zaire strain of Ebola virus (ZEBOV) has emerged repeatedly into human populations in central Africa and caused massive die-offs of gorillas and chimpanzees.
Leslie A Real, Paul Harvey, Peter D Walsh, Roman Biek   +3 more
core   +5 more sources

Morphology of Marburg Virus NP–RNA

Virology, 2002
When Marburg virus (MBGV) nucleoprotein (NP) is expressed in insect cells, it binds to cellular RNA and forms NP-RNA complexes such as insect cell-expressed nucleoproteins from other nonsegmented negative-strand RNA viruses. Recombinant MBGV NP-RNA forms loose coils that resemble rabies virus N-RNA.
Larissa Kolesnikova, Manos Mavrakis, Rob W.H. Ruigrok, Guy Schoehn, Stephan Becker   +4 more
openaire   +3 more sources