Results 51 to 60 of about 16,396 (225)

Second Attempt at America First: Donald Trump and the Survival of International Organizations

Global Policy, EarlyView.
ABSTRACT The second Trump administration poses an existential challenge to many international organizations (IOs), putting them at risk of no longer being able to perform their core functions. Compared to the first term, the scope of America First is much wider and the speed much faster.
Hylke Dijkstra
wiley   +1 more source

Maternal, childhood and adolescent influences on Leydig cell functional capacity and circulating INSL3 concentration in young adults: Importance of childhood infections and body mass index

Andrology, EarlyView.
Abstract Background The constitutive Leydig cell hormone insulin‐like peptide 3 (INSL3) is considered a good estimate of the adult Leydig cell functional capacity and appears to remain relatively consistent throughout adult male life, only gradually declining into old age.
Richard Ivell, Bilal Tulumcu, Waleed Alhujaili, Ravinder Anand‐Ivell   +3 more
wiley   +1 more source

Healthy Aging Men Do Not Suffer From Relevant Limitations of Their Reproductive Functions

Andrology, EarlyView.
Abstract Background While metabolic disorders are well‐established contributors to testosterone decline and erectile dysfunction (ED), little is known about the natural progression of reproductive parameters in healthy aging men. Objectives This study aimed to evaluate longitudinal changes in reproductive parameters and sought to determine the ...
Simone Bier, Jann‐Frederik Cremers, Phillip Schrage, Amelie Körtje, Claudia Krallmann, Sabine Kliesch, Jörg Gromoll, Sandra Laurentino, Michael Zitzmann   +8 more
wiley   +1 more source

The Current Pathogenicity and Potential Risk Evaluation of Marburg Virus to Cause Mysterious “Disease X”—An Update on Recent Evidences

Environmental Health Insights
The World Health Organization (WHO) defined Disease X as an upcoming disease with the potential to cause a pandemic. Pathogen X is responsible for Disease X.
Rahima Akter Mitu, Md. Rabiul Islam
doaj   +1 more source

Strengthening global health resilience: Marburg virus-like particle vaccines and the One Health approach

Science in One Health
The Marburg virus (MARV), belonging to the Filoviridae family, poses a significant global health threat, emphasizing the urgency to develop Marburg virus-like particle (VLP) vaccines for outbreak mitigation.
Ram Bahadur Khadka, Khimdhoj Karki, Jitendra Pandey, Rabin Gyawali, Gautam Prasad Chaudhary   +4 more
doaj   +1 more source

A mathematical model of Marburg virus disease outbreaks and the potential role of vaccination in control

BMC Medicine, 2023
Background Marburg virus disease is an acute haemorrhagic fever caused by Marburg virus. Marburg virus is zoonotic, maintained in nature in Egyptian fruit bats, with occasional spillover infections into humans and nonhuman primates.
George Y. Qian, W. John Edmunds, Daniel G. Bausch, Thibaut Jombart   +3 more
doaj   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

In silico exploration of deep-sea fungal metabolites as inhibitor of Ebola and Marburg VP35 and VP40.

PLoS ONE
VP30 and VP40 proteins of Ebola and Marburg viruses have been recognized as potential targets for antiviral drug development due to their essential roles in the viral lifecycle.
Abdullah R Alanzi, Mohammed F Alajmi, Mohammed S Al-Dosari, Mohammad K Parvez, Moneerah J Alqahtani   +4 more
doaj   +1 more source

How severe and prevalent are Ebola and Marburg viruses? A systematic review and meta-analysis of the case fatality rates and seroprevalence

BMC Infectious Diseases, 2016
Background Ebola and Marburg virus diseases are said to occur at a low prevalence, but are very severe diseases with high lethalities. The fatality rates reported in different outbreaks ranged from 24–100%.
Luke Nyakarahuka, Clovice Kankya, Randi Krontveit, Benjamin Mayer, Frank N. Mwiine, Julius Lutwama, Eystein Skjerve   +6 more
doaj   +1 more source

Impacts of bat use of anthropogenic structures on bats and humans

Conservation Biology, EarlyView.
Abstract Human‐induced landscape modifications and climate change are forcing wildlife into closer contact with humans as the availability of natural habitats decreases. Although the importance of anthropogenic structures for the conservation of species is widely recognized, negative narratives surrounding bats may impede conservation efforts in human ...
Ella A. Sippola, Joseph S. Johnson, Stefano Mammola, Grzegorz Apoznański, Ilze Brila, Ignacio Fernández Latapiat, Piia Lundberg, Mariia Matlova, Veronica Nanni, Reilly T. Jackson, Janette Perez‐Jimenez, Sonia Sánchez‐Navarro, Elena Tena, Tanya S. Troitsky, Thomas M. Lilley, Melissa B. Meierhofer   +15 more
wiley   +1 more source