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Marburg Virus Disease: A Narrative Review [PDF]

Health Science Reports
Background and Aims Given the recent deadly outbreaks of the Marburg virus (MARV), in early 2023 in Tanzania and Equatorial Guinea, and the most recent one in Rwanda in 2024, there has been renewed attention across Africa on the threat posed by the re ...
Arash Letafati, Somayeh Sadat Hosseini Fakhr, Ali Qaraee Najafabadi, Negin Karami, Hassan Karami   +4 more
doaj   +4 more sources

Outbreak of Marburg Virus Disease, Equatorial Guinea, 2023 [PDF]

Emerging Infectious Diseases
In February 2023, the government of Equatorial Guinea declared an outbreak of Marburg virus disease. We describe the response structure and epidemiologic characteristics, including case-patient demographics, clinical manifestations, risk factors, and ...
Stephanie Ngai, Egmond Samir Evers, Angela Katherine Lao Seoane, George Ameh, Julienne N. Anoko, Céline Barnadas, Mary J. Choi, Janet Diaz, Luca Fontana, Pierre Formenty, Ingrid Hammermeister Nezu, Frédérique Jacquerioz, John Klena, Henry Laurenson-Schafer, Olivier le Polain de Waroux, Anaïs Legand, Raquel Medialdea Carrera, Tatiana Metcalf, Joel Montgomery, Silvia Morreale, María E. Negrón, Justino Obama Nvé, Mitoha Ondo’o Ayekaba, Boris I. Pavlin, Trevor Shoemaker, Yaimara Torres Hernandez, Mabel Varona Venta, Emily Z. Gutierrez, Florentino Abaga Ondo Ndoho   +28 more
doaj   +4 more sources

Marburg virus disease: A summary for clinicians [PDF]

International Journal of Infectious Diseases, 2020
Objectives: This article summarizes the countermeasures for Marburg virus disease, focusing on pathogenesis, clinical features and diagnostics. There is an emphasis on therapies and vaccines that have demonstrated, through their evaluation in nonhuman ...
Mark G. Kortepeter, Kerry Dierberg, Erica S. Shenoy, Theodore J. Cieslak   +3 more
doaj   +3 more sources

A mathematical model of Marburg virus disease outbreaks and the potential role of vaccination in control [PDF]

BMC Medicine, 2023
Background Marburg virus disease is an acute haemorrhagic fever caused by Marburg virus. Marburg virus is zoonotic, maintained in nature in Egyptian fruit bats, with occasional spillover infections into humans and nonhuman primates.
George Y. Qian, W. John Edmunds, Daniel G. Bausch, Thibaut Jombart   +3 more
doaj   +2 more sources

A surrogate BSL2-compliant infection model recapitulating key aspects of human Marburg virus disease [PDF]

Emerging Microbes and Infections
Marburg virus disease (MVD) is a severe infectious disease caused by the Marburg virus (MARV), posing a significant threat to humans. MARV needs to be operated under strict biosafety Level 4 (BSL-4) laboratory conditions.
Wanying Yang, Wujie Zhou, Bo Liang, Xiaojun Hu, Shen Wang, Zhenshan Wang, Tiecheng Wang, Xianzhu Xia, Na Feng, Yongkun Zhao, Feihu Yan   +10 more
doaj   +2 more sources

Marburg Virus Disease: Epidemiology, Immune Responses, and Innovations in Vaccination and Treatment for Enhanced Public Health Strategies [PDF]

Pathogens
Marburg virus disease (MVD) remains an important global health concern, in part because of its particularly high mortality rate [...]
Tafadzwa Dzinamarira, Claude Mambo Muvunyi   +1 more
doaj   +2 more sources

Computed Tomography Imaging for Monitoring of Marburg Virus Disease: a Nonhuman Primate Proof-Of-Concept Study [PDF]

Microbiology Spectrum, 2023
Marburg virus (MARV) is a highly virulent zoonotic filovirid that causes Marburg virus disease (MVD) in humans. The pathogenesis of MVD remains poorly understood, partially due to the low number of cases that can be studied, the absence of state-of-the ...
Jennifer Sword, Ji Hyun Lee, Marcelo A. Castro, Jeffrey Solomon, Nina Aiosa, Syed M. S. Reza, Winston T. Chu, Joshua C. Johnson, Christopher Bartos, Kurt Cooper, Peter B. Jahrling, Reed F. Johnson, Claudia Calcagno, Ian Crozier, Jens H. Kuhn, Lisa E. Hensley, Irwin M. Feuerstein, Venkatesh Mani   +17 more
doaj   +2 more sources

Marburg virus disease: the paradox of Nigeria’s preparedness and priority effects in co-epidemics [PDF]

Bulletin of the National Research Centre, 2023
Background The recent outbreaks of Marburg virus disease (MVD) in Guinea and Ghana have become a major public health concern not only to the West African sub-region but a threat to global health.
Rine Christopher Reuben, Sarah Adamma Abunike   +1 more
doaj   +2 more sources

Marburg Virus Disease outbreaks, mathematical models, and disease parameters: a Systematic Review [PDF]

The Lancet Infectious Diseases, 2023
AbstractBackgroundRecent Marburg virus disease (MVD) outbreaks in Equatorial Guinea and Tanzania highlighted the importance of better understanding this highly lethal infectious pathogen. Past epidemics of Ebola, COVID-19, and other pathogens have re-emphasised the usefulness of mathematical models in guiding public health responses during outbreaks ...
Cuomo-Dannenburg G, McCain K, McCabe R, Unwin HJT, Doohan P, Nash RK, Hicks JT, Charniga K, Geismar C, Lambert B, Nikitin D, Skarp J, Wardle J, Pathogen Epidemiology Review Group, Kont M, Bhatia S, Imai N, van Elsland S, Cori A, Morgenstern C.   +19 more
europepmc   +6 more sources

Marburg virus and the disease it causes

Журнал микробиологии, эпидемиологии и иммунобиологии, 2022
Over the 50 years since its discovery, many properties of the Marburg virus have been studied, but no reliable medical remedies of preventing and treating the infection it causes have been developed, although it can potentially cause large-scale ...
Vladimir A. Markin
doaj   +2 more sources