Results 1 to 10 of about 480,468 (239)

Marburg Virus Disease: A Narrative Review. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Given the recent deadly outbreaks of the Marburg virus (MARV), in early 2023 in Tanzania and Equatorial Guinea, and the most recent one in Rwanda in 2024, there has been renewed attention across Africa on the threat posed by the re‐emergence of MARV as a growing concern for public health.
Letafati A, Fakhr SSH, Najafabadi AQ, Karami N, Karami H.   +4 more
europepmc   +4 more sources

A mathematical model of Marburg virus disease outbreaks and the potential role of vaccination in control. [PDF]

BMC Med, 2023
Background Marburg virus disease is an acute haemorrhagic fever caused by Marburg virus. Marburg virus is zoonotic, maintained in nature in Egyptian fruit bats, with occasional spillover infections into humans and nonhuman primates.
Qian GY, Edmunds WJ, Bausch DG, Jombart T.   +3 more
europepmc   +5 more sources

Marburg virus disease: A summary for clinicians. [PDF]

Int J Infect Dis, 2020
Objectives: This article summarizes the countermeasures for Marburg virus disease, focusing on pathogenesis, clinical features and diagnostics. There is an emphasis on therapies and vaccines that have demonstrated, through their evaluation in nonhuman ...
Kortepeter MG, Dierberg K, Shenoy ES, Cieslak TJ, Medical Countermeasures Working Group of the National Ebola Training and Education Center's (NETEC) Special Pathogens Research Network (SPRN).   +4 more
europepmc   +6 more sources

Marburg Virus Disease outbreaks, mathematical models, and disease parameters: a Systematic Review [PDF]

The Lancet Infectious Diseases, 2023
AbstractBackgroundRecent Marburg virus disease (MVD) outbreaks in Equatorial Guinea and Tanzania highlighted the importance of better understanding this highly lethal infectious pathogen. Past epidemics of Ebola, COVID-19, and other pathogens have re-emphasised the usefulness of mathematical models in guiding public health responses during outbreaks ...
Cuomo-Dannenburg G, McCain K, McCabe R, Unwin HJT, Doohan P, Nash RK, Hicks JT, Charniga K, Geismar C, Lambert B, Nikitin D, Skarp J, Wardle J, Pathogen Epidemiology Review Group, Kont M, Bhatia S, Imai N, van Elsland S, Cori A, Morgenstern C.   +19 more
europepmc   +7 more sources

A surrogate BSL2-compliant infection model recapitulating key aspects of human Marburg virus disease. [PDF]

Emerg Microbes Infect
Marburg virus disease (MVD) is a severe infectious disease caused by the Marburg virus (MARV), posing a significant threat to humans. MARV needs to be operated under strict biosafety Level 4 (BSL-4) laboratory conditions.
Yang W, Zhou W, Liang B, Hu X, Wang S, Wang Z, Wang T, Xia X, Feng N, Zhao Y, Yan F.   +10 more
europepmc   +3 more sources

Computed Tomography Imaging for Monitoring of Marburg Virus Disease: a Nonhuman Primate Proof-Of-Concept Study. [PDF]

Microbiol Spectr, 2023
Marburg virus (MARV) is a highly virulent zoonotic filovirid that causes Marburg virus disease (MVD) in humans. The pathogenesis of MVD remains poorly understood, partially due to the low number of cases that can be studied, the absence of state-of-the ...
Sword J, Lee JH, Castro MA, Solomon J, Aiosa N, Reza SMS, Chu WT, Johnson JC, Bartos C, Cooper K, Jahrling PB, Johnson RF, Calcagno C, Crozier I, Kuhn JH, Hensley LE, Feuerstein IM, Mani V.   +17 more
europepmc   +3 more sources

Marburg Virus Disease Outbreak in Guinea, August 2021

Global Biosecurity, 2022
Marburg Virus Disease (MVD) formerly known as Marburg Virus Haemorrhagic Fever is a zoonotic disease which can lead to a severe form of haemorrhagic fever, causing multi-organ failure and death.
Jessica Yang
doaj   +3 more sources

Potent immunogenicity and protective efficacy of a multi-pathogen vaccination targeting Ebola, Sudan, Marburg and Lassa viruse [PDF]

PLoS Pathogens
Viral haemorrhagic fevers (VHF) pose a significant threat to human health. In recent years, VHF outbreaks caused by Ebola, Marburg and Lassa viruses have caused substantial morbidity and mortality in West and Central Africa.
Appelberg, Sofia, Bibi, Sagida, Cha, Kuan M., Dowall, Stuart, Easterbrook, Linda, Findlay-Wilson, Stephen, Flaxman, Amy, Gilbert, Sarah, Gilbride, Ciaran, Lambe, Teresa, Mirazimi, Ali, Purushotham, Jyothi, Schmidt, Isabel, Sebastian, Sarah, Sharpe, Hannah, Spencer, Alexandra J., Ulaszewska, Marta, Wright, Daniel   +17 more
core   +3 more sources

Marburg virus and the disease it causes

Журнал микробиологии, эпидемиологии и иммунобиологии, 2022
Over the 50 years since its discovery, many properties of the Marburg virus have been studied, but no reliable medical remedies of preventing and treating the infection it causes have been developed, although it can potentially cause large-scale ...
Vladimir A. Markin
doaj   +2 more sources

Marburg virus disease outbreaks, mathematical models, and disease parameters: a systematic review. [PDF]

Lancet Infect Dis
The 2023 Marburg virus disease outbreaks in Equatorial Guinea and Tanzania highlighted the importance of better understanding this lethal pathogen.
Cuomo-Dannenburg G, McCain K, McCabe R, Unwin HJT, Doohan P, Nash RK, Hicks JT, Charniga K, Geismar C, Lambert B, Nikitin D, Skarp J, Wardle J, Kont M, Bhatia S, Imai N, van Elsland S, Cori A, Morgenstern C, Pathogen Epidemiology Review Group.   +19 more
europepmc   +3 more sources