Results 31 to 40 of about 12,843 (160)

Marburg Virus and Monkeypox Virus: The Concurrent Outbreaks in Ghana and the lesson learned from the Marburg Virus Containment

Journal of Pure and Applied Microbiology, 2022
Ghana, a country in the African continent experienced its first ever outbreak of Marburg Virus disease on July 2022. Prior to this, Democratic Republic of Congo and Angola were the two most severely affected countries to be affected by the same disease ...
Ranjit Sah, Abdullah Reda, Basant Ismail Lashin, Abdelaziz Abdelaal, Aroop Mohanty, Abdelmonem Siddiq, Bijaya Kumar Padhi   +6 more
doaj   +1 more source

Approaches to demonstrating the effectiveness of filovirus vaccines: Lessons from Ebola and COVID-19

Frontiers in Immunology, 2023
Zaire ebolavirus (EBOV), Sudan ebolavirus (SUDV) and Marburg virus (MARV), are members of the Filoviridae family that can cause severe disease and death in humans and animals.
Marion F. Gruber, Steven Rubin, Philip R. Krause   +2 more
doaj   +1 more source

Marburg Virus Disease – A Mini-Review

Journal of Experimental Biology and Agricultural Sciences, 2022
Marburg virus disease (MVD) is a highly fatal disease caused by the Marburg virus (MARV) which belongs to the family Filoviridae. The disease has been recently reported from Ghana, an African country, and nearly 15 outbreaks of MVD have been reported in the past five decades. Various species of bats viz., Rousettus aegyptiacus, Hipposideros caffer, and
Sandip Chakraborty, Deepak Chandran, Ranjan K. Mohapatra, Mahmoud Alagawany, Mohd Iqbal Yatoo, Md. Aminul Islam, Anil K. Sharma, Kuldeep Dhama   +7 more
openaire   +1 more source

Computed Tomography Imaging for Monitoring of Marburg Virus Disease: a Nonhuman Primate Proof-Of-Concept Study

Microbiology Spectrum, 2023
Marburg virus (MARV) is a highly virulent zoonotic filovirid that causes Marburg virus disease (MVD) in humans. The pathogenesis of MVD remains poorly understood, partially due to the low number of cases that can be studied, the absence of state-of-the ...
Jennifer Sword, Ji Hyun Lee, Marcelo A. Castro, Jeffrey Solomon, Nina Aiosa, Syed M. S. Reza, Winston T. Chu, Joshua C. Johnson, Christopher Bartos, Kurt Cooper, Peter B. Jahrling, Reed F. Johnson, Claudia Calcagno, Ian Crozier, Jens H. Kuhn, Lisa E. Hensley, Irwin M. Feuerstein, Venkatesh Mani   +17 more
doaj   +1 more source

Enhancing Global Health Security in Sub-Saharan Africa: The case for integrated One Health surveillance against zoonotic diseases and environmental threats

One Health
Integrated One Health surveillance is pivotal to Africa's future health security, particularly in preventing and managing zoonotic and environmental health threats.
Pierre Gashema, Placide Sesonga, Patrick Gad Iradukunda, Richard Muvunyi, Jean Claude Mugisha, Jerome Ndayisenga, Tumusime Musafiri, Richard Habimana, Radjabu Bigirimana, Alice Kabanda, Misbah Gashegu, Noel Gahamanyi, Jonathan Izudi, Emmanuel Edwar Siddig, Jean Claude Semuto Ngabonziza, Ayman Ahmed, Tafadzwa Dzinamarira, Leon Mutesa, Claude Mambo Muvunyi   +18 more
doaj   +1 more source

A retrospective cohort investigation of seroprevalence of Marburg virus and ebolaviruses in two different ecological zones in Uganda

BMC Infectious Diseases, 2020
Background Uganda has experienced seven Ebola Virus Disease (EVD) outbreaks and four Marburg Virus Disease (MVD) outbreaks between 2000 and 2019. We investigated the seroprevalence and risk factors for Marburg virus and ebolaviruses in gold mining ...
Luke Nyakarahuka, Ilana J. Schafer, Stephen Balinandi, Sophia Mulei, Alex Tumusiime, Jackson Kyondo, Barbara Knust, Julius Lutwama, Pierre Rollin, Stuart Nichol, Trevor Shoemaker   +10 more
doaj   +1 more source

Forty-Five Years of Marburg Virus Research

Viruses, 2012
In 1967, the first reported filovirus hemorrhagic fever outbreak took place in Germany and the former Yugoslavia. The causative agent that was identified during this outbreak, Marburg virus, is one of the most deadly human pathogens.
Kristina Brauburger, Adam J. Hume, Judith Olejnik, Elke Mühlberger   +3 more
doaj   +1 more source

Experimental Vaccines for Prevention of Marburg Hemorrhagic Fever and Animal Models for Studying Pathogenesis

Проблемы особо опасных инфекций, 2018
Marburg fever is an acute natural-focal disease characterized by severe course, hemorrhagic syndrome, high level of contagiousness and lethality. The causative agent of the disease is the RNA-containing virus belonging to the family of filoviruses ...
N. V. Volkova, E. I. Kazachinskaya, D. N. Shcherbakov   +2 more
doaj   +1 more source

How severe and prevalent are Ebola and Marburg viruses? A systematic review and meta-analysis of the case fatality rates and seroprevalence

BMC Infectious Diseases, 2016
Background Ebola and Marburg virus diseases are said to occur at a low prevalence, but are very severe diseases with high lethalities. The fatality rates reported in different outbreaks ranged from 24–100%.
Luke Nyakarahuka, Clovice Kankya, Randi Krontveit, Benjamin Mayer, Frank N. Mwiine, Julius Lutwama, Eystein Skjerve   +6 more
doaj   +1 more source

Refining a preclinical model of viral myocarditis in accordance with biotech standards

Animal Models and Experimental Medicine, EarlyView.
This study aimed to refine a murine model of Coxsackievirus B3‐induced myocarditis by integrating dietary and imaging innovations to improve animal welfare, data quality, and clinical applicability. The refined diet significantly reduced animal health burden, reduced weight loss, and stabilized blood glucose during development of cardiac inflammation ...
Jonas Stewen, Julia Riedesel, Juliane Stein, Brandon H. Greene, Svenja Rohde, Sonja Suess, Bjoern Keiner, Priya Panjwani, Padmapriya Ponnuswamy, Juan E. Camacho Londoño   +9 more
wiley   +1 more source