Results 51 to 60 of about 12,843 (160)

Characterization of Ravn virus viral shedding dynamics in experimentally infected Egyptian rousette bats (Rousettus aegypticus)

Journal of Virology
Marburg virus (MARV) and Ravn virus (RAVV), the only two known members of the species Orthomarburgvirus marburgense (family Filoviridae), are causative agents of Marburg virus disease, a severe viral disease that typically emerges in sub-Saharan Africa ...
Jessica A. Elbert, Amy J. Schuh, Brian R. Amman, Jonathan C. Guito, James C. Graziano, Tara K. Sealy, Elizabeth W. Howerth, Jonathan S. Towner   +7 more
doaj   +1 more source

Variant‐Specific Landscape of Mutual Exclusivity Among BRAF, EGFR, and KRAS Oncogenes Reveals Overlap With Functionally Antagonistic Mutant Pairs

International Journal of Cancer, Volume 159, Issue 7, Page 1715-1734, 1 October 2026.
Mutual exclusivity and co‐occurrence of oncogenic mutations reflect functional antagonism or dependence and may inform therapeutic strategies. However, most studies overlook variant‐level patterns. In this comprehensive, cross‐cohort analysis of BRAF, KRAS, and EGFR mutation subtypes, the most significant mutual exclusivity pairs overlapped with ...
Freya Vaeyens, Jan‐Patrick Hetzel, Khaldoon Abdullah, Carolien Eggermont, Catharina Olsen, Marco Mernberger, Ken Maes, Jelle Vlaeminck, Rainer Claus, Dries Vanisterbecq, Frederik Hes, Martin Pichler, Philippe Giron, Oleg Timofeev, Maxim Noeparast   +14 more
wiley   +1 more source

Development of an Immunochromatography Assay to Detect Marburg Virus and Ravn Virus

Viruses, 2023
The recent outbreaks of Marburg virus disease (MVD) in Guinea, Ghana, Equatorial Guinea, and Tanzania, none of which had reported previous outbreaks, imply increasing risks of spillover of the causative viruses, Marburg virus (MARV) and Ravn virus (RAVV),
Katendi Changula, Masahiro Kajihara, Shino Muramatsu, Koji Hiraoka, Toru Yamaguchi, Yoko Yago, Daisuke Kato, Hiroko Miyamoto, Akina Mori-Kajihara, Asako Shigeno, Reiko Yoshida, Corey W. Henderson, Andrea Marzi, Ayato Takada   +13 more
doaj   +1 more source

Healthy Aging Men Do Not Suffer From Relevant Limitations of Their Reproductive Functions

Andrology, Volume 14, Issue 6, Page 1504-1514, September 2026.
ABSTRACT Background While metabolic disorders are well‐established contributors to testosterone decline and erectile dysfunction (ED), little is known about the natural progression of reproductive parameters in healthy aging men. Objectives This study aimed to evaluate longitudinal changes in reproductive parameters and sought to determine the ...
Simone Bier, Jann‐Frederik Cremers, Phillip Schrage, Amelie Körtje, Claudia Krallmann, Sabine Kliesch, Jörg Gromoll, Sandra Laurentino, Michael Zitzmann   +8 more
wiley   +1 more source

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

Advanced Science, Volume 13, Issue 44, 7 August 2026.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth, Christoph F. Jacob, Alexandra Nguyen, Mandy Beyer, Andreas O. Mieland, Mario Dejung, Jia‐Xuan Chen, Walburgis Brenner, Christina Ehrhardt, Andreas Henke, Oliver H. Krämer   +10 more
wiley   +1 more source

One Health Insights From Pteropus medius: Nipah Virus Spillover, Microbiota, and Antimicrobial Resistance

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Environmental and anthropogenic drivers of antibiotic resistance dissemination. The cycle reinforces how anthropogenic inputs, such as sewage, animal dung, hospital effluent, and agricultural runoff bring resistant bacteria and antibiotic residues into soil and water.
Punam Chowdhury, Shah Md Tanvir Khan, Sajal Roy, Md. Shohel Al Faruk   +3 more
wiley   +1 more source

Rwanda’s lessons for strengthening Africa’s response to current Marburg virus disease outbreaks

The Lancet Global Health
Summary: Marburg virus disease remains a major threat to global health security in Africa, where recurrent filovirus outbreaks intersect with fragile health systems.
Claude Mambo Muvunyi, Prof, Pierre Gashema, MSc, Eric Seruyange, PhD, ProfPhD Theogene Twagirumugabe, PhD, Isabelle Mukagatare, MD, Patrick Gad Iradukunda, MSc, Radjabu Bigirimana, MD, Emmanuel Edwar Siddig, PhD, Edson Rwagasore, MD, Jean de Dieu Harelimana, PhD, ProfPhD Sanctus Musafiri, PhD   +10 more
doaj   +1 more source

A Comprehensive Evaluation of Adiposity Indices on 20‐Year Cumulative Incidence of Type 2 Diabetes: The ATTICA Cohort Study (2002–2022)

Clinical Obesity, Volume 16, Issue 4, August 2026.
ABSTRACT The aim of this study was to evaluate the association between indices of adiposity and 20‐year cumulative incidence of type 2 diabetes (T2D) among apparently healthy adults participating in the ATTICA cohort study (2002–2022). The present analysis included data from 2000 individuals free of atherosclerotic cardiovascular disease (ASCVD) and ...
Ioanna Kechagia, Sofia‐Panagiota Giannakopoulou, Fotios Barkas, Mary Yannakoulia, Evangelos Liberopoulos, Petros P. Sfikakis, Christos Pitsavos, Demosthenes Panagiotakos   +7 more
wiley   +1 more source

BCX4430 – A broad-spectrum antiviral adenosine nucleoside analog under development for the treatment of Ebola virus disease

Journal of Infection and Public Health, 2016
Summary: The adenosine nucleoside analog BCX4430 is a direct-acting antiviral drug under investigation for the treatment of serious and life-threatening infections from highly pathogenic viruses, such as the Ebola virus.
Raymond Taylor, Pravin Kotian, Travis Warren, Rekha Panchal, Sina Bavari, Justin Julander, Sylvia Dobo, Angela Rose, Yahya El-Kattan, Brian Taubenheim, Yarlagadda Babu, William P. Sheridan   +11 more
doaj   +1 more source

Mapping the zoonotic niche of Marburg virus disease in Africa [PDF]

Transactions of The Royal Society of Tropical Medicine and Hygiene, 2015
Marburg virus disease (MVD) describes a viral haemorrhagic fever responsible for a number of outbreaks across eastern and southern Africa. It is a zoonotic disease, with the Egyptian rousette (Rousettus aegyptiacus) identified as a reservoir host.
Pigott, DM, Golding, N, Mylne, A, Huang, Z, Weiss, DJ, Brady, OJ, Kraemer, MUG, Hay, SI   +7 more
openaire   +4 more sources