Combination therapy protects macaques against advanced Marburg virus disease. [PDF]
AbstractMonoclonal antibodies (mAbs) and remdesivir, a small-molecule antiviral, are promising monotherapies for many viruses, including members of the genera Marburgvirus and Ebolavirus (family Filoviridae), and more recently, SARS-CoV-2. One of the major challenges of acute viral infections is the treatment of advanced disease.
Cross RW+15 more
europepmc +7 more sources
Qualitative insights on emergency preparedness and response to marburg virus disease in Ghana: The role of risk communication and community engagement. [PDF]
ObjectivesFaith-based healthcare providers have played pivotal roles in recent public health responses to disease outbreaks, such as Ebola, COVID-19, and Marburg Virus Disease. However, the literature on their performance remains scarce.
Agboh HNK, Adjei-Okai G, Adjei GA.
europepmc +4 more sources
Marburg virus disease treatments and vaccines: recent gaps and implications. [PDF]
Marburg virus disease (MVD), caused by the Marburg virus (MARV) of the Filoviridae ...
Albakri K+9 more
europepmc +5 more sources
A Forgotten Episode of Marburg Virus Disease: Belgrade, Yugoslavia, 1967. [PDF]
In 1967, several workers involved in poliomyelitis vaccine development and production fell ill at three different locations in Europe with a severe and often lethal novel disease associated with grivets (Chlorocebus aethiops) imported from Uganda. This disease was named Marburg virus disease (MVD) after the West German town of Marburg an der Lahn ...
Ristanović ES+4 more
europepmc +7 more sources
Marburg virus disease: the paradox of Nigeria's preparedness and priority effects in co-epidemics. [PDF]
Background The recent outbreaks of Marburg virus disease (MVD) in Guinea and Ghana have become a major public health concern not only to the West African sub-region but a threat to global health.
Reuben RC, Abunike SA.
europepmc +3 more sources
The neglected continuously emerging Marburg virus disease in Africa: A global public health threat. [PDF]
Background and Aim Severe viral hemorrhagic fever (VHF) is caused by Marburg virus which is a member of the Filoviridae (filovirus) family. Many Marburg virus disease (MVD) outbreaks are reported in five decades. A major notable outbreak with substantial
Srivastava D+12 more
europepmc +3 more sources
A Cloned Recombinant Vesicular Stomatitis Virus-Vectored Marburg Vaccine, PHV01, Protects Guinea Pigs from Lethal Marburg Virus Disease. [PDF]
Marburg virus (MARV) is a negative-sense, single-stranded RNA virus that belongs to the Filoviridae family. Despite having caused numerous outbreaks of severe hemorrhagic fever with high case fatality rates, there are still no clinically approved therapeutics or vaccines to treat or prevent MARV disease. Recombinant vesicular stomatitis viruses (rVSVs)
Zhu W+10 more
europepmc +6 more sources
Marburg Virus Disease – A Mini-Review [PDF]
Marburg virus disease (MVD) is a highly fatal disease caused by the Marburg virus (MARV) which belongs to the family Filoviridae. The disease has been recently reported from Ghana, an African country, and nearly 15 outbreaks of MVD have been reported in ...
Alagawany, Mahmoud+7 more
core +4 more sources
Marburg Virus Disease: Epidemiology, Immune Responses, and Innovations in Vaccination and Treatment for Enhanced Public Health Strategies. [PDF]
Marburg virus disease (MVD) remains an important global health concern, in part because of its particularly high mortality rate [...]
Dzinamarira T, Muvunyi CM.
europepmc +3 more sources
Marburg virus disease Mayhem: A new threat emerges in Rwanda. [PDF]
Kumar P+6 more
europepmc +5 more sources