A bioluminescent imaging mouse model for Marburg virus based on a pseudovirus system
Human Vaccines & Immunotherapeutics, 2017 Marburg virus (MARV) can cause lethal hemorrhagic fever in humans. Handling of MARV is restricted to high-containment biosafety level 4 (BSL-4) facilities, which greatly impedes research into this virus.
Li Zhang +5 more
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Early human B cell response to Ebola virus in four U.S. survivors of infection [PDF]
, 2019 The human B cell response to natural filovirus infections early after recovery is poorly understood. Previous serologic studies suggest that some Ebola virus survivors exhibit delayed antibody responses with low magnitude and quality.
Bombardi, Robin +14 more
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Marburg virus disease: Is a threatening virus on the way? [PDF]
PayeshDear Editor, Marburg virus (MARV) is a highly lethal virus that causes severe hemorrhagic fever with a high mortality rate. Marburg virus disease is common between humans and livestock (animals) and the reservoir is the Egyptian fruit bat (Rousettus ...
Fatemeh Rahmati, Mahdieh Farzanehpour
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Serological Evidence of Potential Marburg Virus Circulation in Livestock and Dogs in Ghana
PathogensMarburg virus disease (MVD) is a zoonotic hemorrhagic disease with an estimated case fatality rate of up to 88%. Ghana recorded its first human MVD outbreak in June 2022 and although the outbreak was quickly brought under control, the transmission ...
Theophilus Odoom +11 more
doaj +1 more source
Jamaican fruit bats’ competence for Ebola but not Marburg virus is driven by intrinsic differences
Nature CommunicationsEbola virus (EBOV) and Marburg virus (MARV) are zoonotic filoviruses that cause hemorrhagic fever in humans. Correlative data implicate bats as natural EBOV hosts, but neither a full-length genome nor an EBOV isolate has been found in any bats sampled ...
Sarah van Tol +26 more
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Cryo-EM structure of single-layered nucleoprotein-RNA complex from Marburg virus
Nature CommunicationsMarburg virus (MARV) causes lethal hemorrhagic fever in humans, posing a threat to global health. We determined by cryogenic electron microscopy (cryo-EM) the MARV helical ribonucleoprotein (RNP) complex structure in single-layered conformation, which ...
Luca Zinzula +8 more
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Marburg virus (Marburg marburgvirus; MARV) causes sporadic outbreaks of Marburg hemorrhagic fever (MHF) in Africa. The Egyptian fruit bat (Rousettus aegyptiacus) has been identified as a natural reservoir based most-recently on the repeated isolation of ...
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Mission to Indonesia to participate to the 1st Indonesia- France Seminar in Medicine & Public Health and investigate potential collaborations on animal health : 2nd - 9th of November 2012 [PDF]
, 2012 Emerging and zoonotic infectious diseases are a major issue in Indonesia. The objective of this mission, funded by the Institut Français d'Indonésie (IFI), was to identify potential subjects of collaboration between CIRAD, Pasteur Institute, and ...
Bourhy, Hervé +2 more
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Filovirus Research: The Need for an Integrated Approach in Time and Space [PDF]
The episodic appearance of Ebola virus (EBOV) and Marburg virus (MARV) across central Africa over the last 15 years not only underscores the importance of filoviruses as uniquely virulent agents to both human and wildlife communities but also implies a ...
Pinzon, Jorge E.
core +1 more source
Dysregulated and maladaptive immune responses are at the forefront of human diseases caused by infection with zoonotic viral hemorrhagic fever viruses. Elucidating mechanisms of how the natural animal reservoirs of these viruses coexist with these agents
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