Results 81 to 90 of about 1,166,657 (155)

Marburg virus budding: ESCRT of progeny virion to the outside of the cell

open access: yes, 2010
The major virion matrix protein of the Marburg virus (MARV), VP40, plays a key role in MARV assembly and budding, and its sole expression can produce enveloped virus-like particles.
Jiro Yasuda
core   +1 more source

Durability of a vesicular stomatitis virus-based marburg virus vaccine in nonhuman primates.

open access: yes, 2014
The filoviruses, Marburg virus (MARV) and Ebola virus, causes severe hemorrhagic fever with high mortality in humans and nonhuman primates. A promising filovirus vaccine under development is based on a recombinant vesicular stomatitis virus (rVSV) that ...
Lisa E Hensley   +17 more
core   +1 more source

Development of neutralizing monoclonal antibodies (mAbs) against marburg virus [PDF]

open access: yes, 2019
Marburg virus (MARV) causes Marburg virus disease (MVD) in humans and non-human primates. Outbreaks of MVD are intermittent and have mostly happened in Central Africa. The mortality rates of these outbreaks are normally more than 50%.
Zhang, Zirui
core  

Marburg Virus Disease in Sub-Saharan Africa: A Review of Currently Available Comprehensive Genomic Data up to 2024

open access: yesZoonotic Diseases
Marburg virus (MARV) is one of the deadliest human zoonotic pathogens, historically traced back to Uganda, in East African-cave-dwelling Egyptian fruit bats (Rousettus aegyptiacus), the probable cradle of MARV.
Edson Kinimi
doaj   +1 more source

A Single Amino Acid Change in the Marburg Virus Glycoprotein Arises during Serial Cell Culture Passages and Attenuates the Virus in a Macaque Model of Disease

open access: yesmSphere, 2018
Marburg virus (MARV) causes disease with high case fatality rates, and there are no approved vaccines or therapies. Licensing of MARV countermeasures will likely require approval via the FDA’s Animal Efficacy Rule, which requires well-characterized ...
Kendra J. Alfson   +6 more
doaj   +1 more source

Revisiting Ravn virus as the lesser known orthomarburgvirus

open access: yesnpj Viruses
Marburg virus (MARV) is a highly pathogenic zoonotic filovirus. The Orthomarburgvirus marburgense species includes MARV and Ravn virus (RAVV), which differs from MARV by 21% at the nucleotide level and 22% at the protein level.
Ivet A. Yordanova, Joseph B. Prescott
doaj   +1 more source

Serosurvey on household contacts of Marburg hemorrhagic fever patients. [PDF]

open access: yes, 2006
The first major outbreak of Marburg hemorrhagic fever (MHF) outside a laboratory environment occurred in the subdistrict of Watsa, Democratic Republic of Congo, from October 1998 to August 2000.
MULANGU, S   +30 more
core   +1 more source

IN SILICO IDENTIFICATION AND CHARACTERIZATION OF MUTUAL EPITOPE-BASED SUBUNIT VACCINE AGAINST EBOLA VIRUS AND MARBURG VIRUS [PDF]

open access: yes, 2020
Objective: The objective of the study was to analyze the mutual epitope-based vaccine that can evoke immune response against hemorrhagic fever caused by Ebola virus (EBOV) and Marburg virus (MARV).
YADAV, POOJA   +2 more
core   +1 more source

Distribution of Marburg virus in Africa: An evolutionary approach

open access: yes, 2016
The aim of this study was to investigate the origin and geographical dispersion of Marburg virus, the first member of the Filoviridae family to be discovered.
E. Ebranati   +9 more
core   +1 more source

Experimental Success in Marburg Virus Vaccination [PDF]

open access: yes
The Marburg virus (MRV), classified within the Filoviridae family, was initially identified in 1967, precipitating Marburg virus disease (MARV), a severe and often fatal hemorrhagic fever.
Martyna Dydyk, Aleksandra Nowak
core   +3 more sources

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