Results 71 to 80 of about 1,166,657 (155)

The Issue of Screening for Transfusion‐Transmitted Infections in Sub‐Saharan Africa Presents Several Challenges: A Review

open access: yesAdvances in Hematology, Volume 2025, Issue 1, 2025.
Blood transfusion is a vital medical procedure with the potential to save lives; however, it can have serious consequences if not carried out under rigorous principles. Sub‐Saharan Africa (SSA) faces considerable challenges in ensuring the security of the transfusion process, particularly in the context of transfusion‐transmissible infections (TTIs ...
F. Y. Djientcheu Deugoue   +6 more
wiley   +1 more source

Development of a Well-Characterized Cynomolgus Macaque Model of Marburg Virus Disease for Support of Vaccine and Therapy Development

open access: yes, 2022
Marburg virus (MARV) is a filovirus that can infect humans and nonhuman primates (NHPs), causing severe disease and death. Of the filoviruses, Ebola virus (EBOV) has been the primary target for vaccine and therapeutic development.
Goez-Gazi, Yenny   +35 more
core   +1 more source

O‐glycosylation in viruses: A sweet tango

open access: yesmLife, Volume 3, Issue 1, Page 57-73, March 2024.
Abstract O‐glycosylation is an ancient yet underappreciated protein posttranslational modification, on which many bacteria and viruses heavily rely to perform critical biological functions involved in numerous infectious diseases or even cancer. But due to the innate complexity of O‐glycosylation, research techniques have been limited to study its ...
Annan Ming   +6 more
wiley   +1 more source

Is Marburg virus enzootic in Gabon ?

open access: yes, 2011
Marburg virus (MARV) nucleic acid was detected in Rousettus aegyptiacus bats in 2005 and 2006 in the midwest and southeast of Gabon. In this study we used MARV-specific real-time reverse-transcription polyermase chain reaction (RT-PCR) and MARV-specific ...
Bourgarel, M.   +19 more
core   +1 more source

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

open access: yesJournal of Extracellular Vesicles, Volume 13, Issue 2, February 2024.
Abstract Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year‐on‐year increase in the numbers of scientific ...
Joshua A. Welsh   +1125 more
wiley   +1 more source

A rabies virus-vectored vaccine expressing two copies of the Marburg virus glycoprotein gene induced neutralizing antibodies against Marburg virus in humanized mice

open access: yes, 2022
Marburg virus disease (MVD) is a lethal viral haemorrhagic fever caused by Marburg virus (MARV) with a case fatality rate as high as 88%. There is currently no vaccine or antiviral therapy approved for MVD.
Qiuxue Han (10213910)   +12 more
core   +1 more source

Utilizing non‐human primate models to combat recent COVID‐19/SARS‐CoV‐2 and viral infectious disease outbreaks

open access: yesJournal of Medical Primatology, Volume 53, Issue 1, February 2024.
Abstract In recent times, global viral outbreaks and diseases, such as COVID‐19 (SARS‐CoV‐2), Zika (ZIKV), monkeypox (MPOX), Ebola (EBOV), and Marburg (MARV), have been extensively documented. Swiftly deciphering the mechanisms underlying disease pathogenesis and devising vaccines or therapeutic interventions to curtail these outbreaks stand as ...
Taeho Kwon
wiley   +1 more source

Virus-Like Particle Vaccination Protects Nonhuman Primates from Lethal Aerosol Exposure with Marburgvirus (VLP Vaccination Protects Macaques against Aerosol Challenges)

open access: yesViruses, 2016
Marburg virus (MARV) was the first filovirus to be identified following an outbreak of viral hemorrhagic fever disease in Marburg, Germany in 1967. Due to several factors inherent to filoviruses, they are considered a potential bioweapon that could be ...
John M. Dye   +8 more
doaj   +1 more source

Antimicrobial peptides for novel antiviral strategies in the current post‐COVID‐19 pandemic

open access: yesJournal of Peptide Science, Volume 30, Issue 1, January 2024.
This review describes the main physicochemical characteristics of antimicrobial peptides, with particular focus on peptides derived from amphibian skin. Summarizing the various antiviral activities of these peptides and the underlying mechanism, this review emphasizes the high potential of these small molecules for the development of new antiviral ...
Maria Rosa Loffredo   +3 more
wiley   +1 more source

Shedding of Marburg Virus in Naturally Infected Egyptian Rousette Bats, South Africa, 2017 [PDF]

open access: yes, 2020
We detected Marburg virus RNA in rectal swab samples from Egyptian rousette bats in South Africa in 2017. This finding signifies that fecal contamination of natural bat habitats is a potential source of infection for humans.
Palacios, G.   +12 more
core   +1 more source

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