Results 11 to 20 of about 1,166,657 (155)

Preparation of Class Y Immunoglobulins that Neutralize the Marburg Virus [PDF]

Проблемы особо опасных инфекций, 2021
The aim was to study the possibility of inducing Marburg-neutralizing chicken antibodies (MARV) using various immunogens.Materials and methods. Recombinant vaccinia virus expressing the surface glycoprotein (GP) transgene MARV of Musoke strain and ...
O. A. Polezhaeva, A. V. Zybkina, A. V. Zaikovskaya, O. V. P’yankov, S. A. P’yankov, A. V. Semenova, G. V. Semenova, D. N. Shcherbakov   +7 more
doaj   +2 more sources

Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs. [PDF]

PLoS Pathogens, 2015
The filoviruses, which include the marburg- and ebolaviruses, have caused multiple outbreaks among humans this decade. Antibodies against the filovirus surface glycoprotein (GP) have been shown to provide life-saving therapy in nonhuman primates, but ...
Marnie L Fusco, Takao Hashiguchi, Robyn Cassan, Julia E Biggins, Charles D Murin, Kelly L Warfield, Sheng Li, Frederick W Holtsberg, Sergey Shulenin, Hong Vu, Gene G Olinger, Do H Kim, Kevin J Whaley, Larry Zeitlin, Andrew B Ward, Cory Nykiforuk, M Javad Aman, Jody D Berry, Erica Ollmann Saphire   +18 more
doaj   +2 more sources

Studies of Reservoir Hosts for Marburg Virus [PDF]

Emerging Infectious Diseases, 2007
To determine reservoir hosts for Marburg virus (MARV), we examined the fauna of a mine in northeastern Democratic Republic of the Congo. The mine was associated with a protracted outbreak of Marburg hemorrhagic fever during 1998–2000.
Robert Swanepoel, Sheilagh B. Smit, Pierre E. Rollin, Pierre Formenty, Patricia A. Leman, Alan Kemp, Felicity J. Burt, Antoinette A. Grobbelaar, Janice Croft, Daniel G. Bausch, Hervé Zeller, Herwig Leirs, L.E.O. Braack, Modeste L. Libande, Sherif Zaki, Stuart T. Nichol, Thomas G. Ksiazek, Janusz T. Paweska   +17 more
doaj   +2 more sources

Marburg Virus Persistence on Fruit as a Plausible Route of Bat to Primate Filovirus Transmission

Viruses, 2021
Marburg virus (MARV), the causative agent of Marburg virus disease, emerges sporadically in sub-Saharan Africa and is often fatal in humas. The natural reservoir for this zoonotic virus is the frugivorous Egyptian rousette bat (Rousettus aegyptiacus ...
Brian R. Amman, Amy J. Schuh, César G. Albariño, Jonathan S. Towner   +3 more
doaj   +2 more sources

Marburg Virus Infection in Egyptian Rousette Bats, South Africa, 2013–2014 [PDF]

Emerging Infectious Diseases, 2018
We detected a high seroprevalence of Marburg virus (MARV) antibodies in fruit bats in South Africa; 19.1% of recaptured bats seroconverted. The MARV RNA isolated closely resembled the 1975 Ozolin strain.
Janusz T. Pawęska, Petrus Jansen van Vuren, Alan Kemp, Nadia Storm, Antoinette A. Grobbelaar, Michael R. Wiley, Gustavo Palacios, Wanda Markotter   +7 more
doaj   +2 more sources

A surrogate BSL2-compliant infection model recapitulating key aspects of human Marburg virus disease

Emerging Microbes and Infections
Marburg virus disease (MVD) is a severe infectious disease caused by the Marburg virus (MARV), posing a significant threat to humans. MARV needs to be operated under strict biosafety Level 4 (BSL-4) laboratory conditions.
Wanying Yang, Wujie Zhou, Bo Liang, Xiaojun Hu, Shen Wang, Zhenshan Wang, Tiecheng Wang, Xianzhu Xia, Na Feng, Yongkun Zhao, Feihu Yan   +10 more
doaj   +2 more sources

Single-Shot ChAd3-MARV Vaccine in Modified Formulation Buffer Shows 100% Protection of NHPs

Vaccines, 2022
Marburg virus (MARV) is a virus of high human consequence with a case fatality rate of 24–88%. The global health and national security risks posed by Marburg virus disease (MVD) underscore the compelling need for a prophylactic vaccine, but no candidate ...
Courtney L. Finch, Thomas H. King, Kendra J. Alfson, Katie A. Albanese, Julianne N. P. Smith, Paul Smock, Jocelyn Jakubik, Yenny Goez-Gazi, Michal Gazi, John W. Dutton, Elizabeth A. Clemmons, Marc E. Mattix, Ricardo Carrion, Thomas Rudge, Alex Ridenour, Sovann F. Woodin, Ruth Hunegnaw, Nancy J. Sullivan, Rong Xu   +18 more
doaj   +2 more sources

Rodent adapted marburg viruses are lethal in ferrets

npj Viruses
Ferrets are highly susceptible to infection with several orthoebolaviruses, including Ebola virus (EBOV), yet they are refractory to infection with the orthomarburgviruses, Marburg virus (MARV) and Ravn virus.
Zachary Schiffman, Lauren Garnett, Kaylie N. Tran, Jonathan Audet, Kevin Tierney, Kim Azaransky, Shihua He, Logan Banadyga, James E. Strong   +8 more
doaj   +2 more sources

Marburg Virus Reverse Genetics Systems [PDF]

Viruses, 2016
The highly pathogenic Marburg virus (MARV) is a member of the Filoviridae family and belongs to the group of nonsegmented negative-strand RNA viruses.
Kristina Maria Schmidt, Elke Mühlberger
doaj   +2 more sources

Marburg Virus Disease: A Narrative Review

Health Science Reports
Background and Aims Given the recent deadly outbreaks of the Marburg virus (MARV), in early 2023 in Tanzania and Equatorial Guinea, and the most recent one in Rwanda in 2024, there has been renewed attention across Africa on the threat posed by the re ...
Arash Letafati, Somayeh Sadat Hosseini Fakhr, Ali Qaraee Najafabadi, Negin Karami, Hassan Karami   +4 more
doaj   +2 more sources