Marburg virus outbreak in Tanzania: A threat to global health security
Abstract The current Marburg virus (MARV) outbreak in Tanzania served as a stark reminder of the ongoing threat posed by emerging infectious diseases and the urgent need for global health security. The Tanzanian Ministry of Health (MoH) officially declared the outbreak on March 21, 2023.
Majani Edward +6 more
wiley +1 more source
Risk factors for Marburg hemorrhagic fever, Democratic Republic of the Congo. [PDF]
We conducted two antibody surveys to assess risk factors for Marburg hemorrhagic fever in an area of confirmed Marburg virus transmission in the Democratic Republic of the Congo.
Roth, Cathy +64 more
core +1 more source
Marburg-Virus (MARV) und Ebola-Virus (EBOV), Mitglieder der Virusfamilie der Filoviridae, lösen schwere, oft tödlich verlaufende Erkrankungen im Menschen und nicht-menschlichen Primaten aus.
Klüver, Michael +1 more
core +2 more sources
The use of a mobile laboratory unit in support of patient management and epidemiological surveillance during the 2005 Marburg outbreak in Angola [PDF]
Background: Marburg virus (MARV), a zoonotic pathogen causing severe hemorrhagic fever in man, has emerged in Angola resulting in the largest outbreak of Marburg hemorrhagic fever (MHF) with the highest case fatality rate to date.
Feldmann Heinz +41 more
core +1 more source
Development of a T7-Independent MARV Minigenome System
Marburg virus (MARV) is the only known pathogenic filovirus that does not belong to the genus Ebolavirus. It causes a severe hemorrhagic fever that is associated with a high mortality rate (>80%).
Bert Vanmechelen +3 more
doaj +1 more source
A recombinant rabies virus expressing the Marburg Virus Glycoprotein Is dependent upon ADCC for protection against Marburg Virus Disease in a Murine Model [PDF]
Accepted ManuscriptMarburg virus (MARV) is a filovirus related to Ebola virus (EBOV) associated with human hemorrhagic disease. Outbreaks are sporadic and severe, with a reported case mortality rate of upward of 88%.
Hagen, Katie R. +7 more
core +1 more source
Small Molecule Inhibition of Mononegavirales RNA Polymerases
ABSTRACT The order Mononegavirales includes several non‐segmented negative‐sense RNA viruses that are significant human pathogens, whose transcription and replication depend on multifunctional RNA‐dependent RNA polymerase (L protein). Recent discoveries in cryo‐electron microscopy (cryo‐EM) have elucidated the structures of these polymerases and their ...
Claire R. Cao +3 more
wiley +1 more source
Dysregulated and maladaptive immune responses are at the forefront of human diseases caused by infection with zoonotic viral hemorrhagic fever viruses. Elucidating mechanisms of how the natural animal reservoirs of these viruses coexist with these agents
Joseph Prescott +11 more
doaj +1 more source
Cohorts of immature Pteropus bats show interannual variation in Hendra virus serology
Pteropus bat with offspring, photo taken by Manuel Ruiz‐Aravena. Abstract Understanding the drivers of seasonal disease outbreaks remains a fundamental challenge in disease ecology. Periodic outbreaks can be driven by several seasonally varying factors, including pulses of susceptible individuals through births, changes in host behaviour and social ...
Daniel E. Crowley +24 more
wiley +1 more source
Differences in cynomolgus macaque populations used for infectious disease research
Cynomolgus macaques, a species of Old World primate native to southeastern and eastern Asia and the island of Mauritius, are one of the most important nonhuman primate models for infectious disease. Research into the population genetics of cynomolgus macaques has found significant differences between macaques native to different areas, particularly ...
Darcy Quist +4 more
wiley +1 more source

