Results 21 to 30 of about 15,633,118 (243)

Marek’s Disease Virus Virulence Genes Encode Circular RNAs

Journal of Virology, 2022
Circular RNAs (circRNAs) were rediscovered in recent years both in physiological and pathological contexts, such as in cancer. Viral circRNAs are encoded by at least two human herpesviruses, the Epstein Barr virus and the Kaposi’s Sarcoma-associated ...
Alexis S Chasseur, G. Trozzi, Céline Istasse, Astrid Petit, P. Rasschaert, C. Denesvre, B. Kaufer, L. D. Bertzbach, B. Muylkens, D. Coupeau   +9 more
semanticscholar   +1 more source

Effect of Insertion and Deletion in the Meq Protein Encoded by Highly Oncogenic Marek’s Disease Virus on Transactivation Activity and Virulence

Viruses, 2022
Marek’s disease virus (MDV) causes malignant lymphoma in chickens (Marek’s disease, MD). Although MD is currently controlled by vaccination, MDV strains have continuously increased in virulence over the recent decades.
Jumpei Sato, S. Murata, Zhiyuan Yang, B. Kaufer, Sotaro Fujisawa, Hikari Seo, N. Maekawa, T. Okagawa, S. Konnai, N. Osterrieder, M. Parcells, K. Ohashi   +11 more
semanticscholar   +1 more source

Phenotypic characterization of gamma delta (γδ) T cells in chickens infected with or vaccinated against Marek's disease virus.

Virology, 2022
Marek's disease (MD) vaccines reduce the incidence of MD but cannot control virus shedding. To develop new vaccines, it is essential to elucidate mechanisms of immunity to Marek's disease virus (MDV) infection.
Ayumi Matsuyama-Kato, H. Iseki, Nitish Boodhoo, Jegarubee Bavananthasivam, Nadiyah Alqazlan, M. Abdul-Careem, B. Plattner, S. Behboudi, S. Sharif   +8 more
semanticscholar   +1 more source

The Regulatory Microenvironment in Feathers of Chickens Infected with Very Virulent Marek’s Disease Virus

Viruses, 2022
Vaccines against Marek’s disease can protect chickens against clinical disease; however, infected chickens continue to propagate the Marek’s disease virus (MDV) in feather follicles and can shed the virus into the environment.
Jegarubee Bavananthasivam, Nadiyah Alqazlan, Mohammadali Alizadeh, Ayumi Matsuyama-Kato, Jake Astill, Raveendra R. Kulkarni, Shayan Sharif   +6 more
doaj   +1 more source

Occurrence of Marek’s disease in Poland on the basis of diagnostic examination in 2015–2018

Journal of Veterinary Research, 2020
Marek’s disease (MD) is a tumourous disease caused by Marek’s disease virus (MDV) and most commonly described in poultry. The aim of the study was to determine the occurrence of Marek’s disease virus infections in Poland and analyse clinical cases in the
Kozdruń Wojciech, Styś-Fijoł Natalia, Czekaj Hanna, Piekarska Karolina, Niczyporuk Jowita Samanta, Stolarek Agnieszka   +5 more
doaj   +1 more source

Comprehensive profiling analysis of the N6-methyladenosine-modified circular RNA transcriptome in cultured cells infected with Marek’s disease virus

Scientific Reports, 2021
Marek’s disease virus (MDV) induces severe immunosuppression and lymphomagenesis in the chicken, its natural host, and results in a condition that investigated the pathogenesis of MDV and have begun to focus on the expression profiling of circular RNAs ...
Ai'jun Sun, Rui Wang, Shuaikang Yang, Xiaojing Zhu, Ying Liu, M. Teng, Lu-Ping Zheng, Jun Luo, Gaiping Zhang, G. Zhuang   +9 more
semanticscholar   +1 more source

A Novel Effective and Safe Vaccine for Prevention of Marek’s Disease Caused by Infection with a Very Virulent Plus (vv+) Marek’s Disease Virus

Vaccines, 2021
Marek’s disease virus (MDV) is a highly contagious alphaherpesvirus that causes rapid onset lymphoma in chickens. Marek’s disease (MD) is effectively controlled using vaccination; however, MDV continues to break through vaccinal immunity, due to the ...
Yi-Fei Liao, S. Reddy, Owais A. Khan, Ai'jun Sun, B. Lupiani   +4 more
semanticscholar   +1 more source

The Functionality of Marek's Disease Virus Us3 Protein [PDF]

, 2007
Marek's disease (MD) is a lymphoproliferative disease of chickens caused by cell-associated Marek's disease virus (MDV). The Us3 protein kinase expressed by MDV has been shown to be involved in various stages of the viral life cycle.
McKinney, Caleb
core   +6 more sources

Genetic variability of the Avian leukosis virus subgroup J gp85 gene in layer flocks in Lower Egypt [PDF]

Veterinary World, 2020
Aim: This study aimed to determine the prevalence of layer flock tumor disease in Lower Egypt during the period of 2018- 2019 and to undertake molecular characterization and determine the genetic diversity of all identified viruses.
Nahed Yehia, Hemat S. El-Sayed, Sabry E. Omar, Fatma Amer   +3 more
doaj   +1 more source

Latest Insights into Marek’s Disease Virus Pathogenesis and Tumorigenesis

Cancers, 2020
Marek’s disease virus (MDV) infects chickens and causes one of the most frequent cancers in animals. Over 100 years of research on this oncogenic alphaherpesvirus has led to a profound understanding of virus-induced tumor development.
L. D. Bertzbach, Andelé M. Conradie, Yu-qin You, B. Kaufer   +3 more
semanticscholar   +1 more source