Results 31 to 40 of about 3,050 (168)
Advanced Materials, EarlyView.A multifunctional bioactive PEEK‐based implant (Mn@p/MBG‐SPEEK) is engineered to combat implant‐associated infections while promoting osteogenesis. The hybrid surface activates PI3K/Akt/mTOR and AP‐1 signaling pathways for osteogenic differentiation, while Mn coordination induces electronic coupling that narrows the HOMO‐LUMO energy gap and enhances ...
Zhiyan Xu +7 more
wiley +1 more source
A Marek’s Disease Vaccination Trial
Poultry Science, 1973 Abstract The New Brunswick Poultry Test Station was utilized to examine the protection afforded by a Marek’s disease vaccine administered to day old chicks via the subcutaneous route. Four commercial Leghorn-type strains of chickens were used. The vaccine was equally effective in all strains in affording protection during the brooding and growing ...
J E, Lancaster, W K, Barr, B R, Bartlett
openaire +2 more sources
The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding
Animal Research and One Health, EarlyView.A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang +10 more
wiley +1 more source
Marek's disease herpesviruses. IV. Molecular characterization of Marek's disease herpesvirus A antigen [PDF]
Journal of Virology, 1983 Marek's disease herpesvirus A antigen (MDHV-A) was identified as a 61,000- to 65,000-dalton glycoprotein by sodium dodecyl sulfate-polyacrylamide gel electrophoresis after immunoprecipitation from the culture medium of both [35S]methionine- and [14C]glucosamine-labeled infected cells by specific rabbit serum directed against MDHV-A.
C, Glaubiger, K, Nazerian, L F, Velicer
openaire +2 more sources
Organelle‐Resolved Tetrazine‐trans‐Cyclooctene Click Chemistry for Cargo Delivery and Release
Chemistry – A European Journal, EarlyView.Bioorthogonal click chemistry tools provide a means for specific intracellular conjugation of molecules. In this study, we used reactive tetrazine (Tz) and TCO moieties for labeling of organelles and organelle‐specific delivery and activation of doxorubicin prodrugs.
Oleh Durydivka +6 more
wiley +1 more source
Corticocortical evoked potential amplitude is altered by cortical stimulation in epilepsy
Epilepsia, EarlyView.Abstract Objective Neurostimulation is an established therapy for drug‐resistant epilepsy, but optimizing stimulation parameters remains a major challenge. Corticocortical evoked potential (CCEP) amplitude may serve as an immediate biomarker of neurostimulation effects, enabling rapid parameter optimization.
Bethany J. Stieve +4 more
wiley +1 more source
Virology Journal, 2011 Background Marek's disease virus (MDV) causes an acute lymphoproliferative disease in chickens, resulting in immunosuppression, which is considered to be an integral aspect of the pathogenesis of Marek's disease (MD).
Cui Zhizhong +5 more
doaj +1 more source
Histone methylation analysis and pathway predictions in chickens after MDV infection. [PDF]
PLoS ONE, 2012 Marek's disease (MD) is a lymphoproliferative disease in chicken induced by Marek's disease virus (MDV). Although studies have focused on the genetic differences between the resistant and susceptible chicken, less is known about the role of epigenetic ...
Juan Luo +8 more
doaj +1 more source
Temperature-induced reactivation of Marek's disease virus-transformed T cells ex vivo
Frontiers in Veterinary Science, 2023 Marek's disease virus (MDV) establishes latency in chicken T lymphocytes that can lead to T cell transformation and cancer. Transformed Marek's disease chicken cell lines (MDCCs) can be expanded ex vivo and provide a valuable model to study latency ...
Yung-Tien Tien +2 more
doaj +1 more source
Head &Neck, EarlyView.ABSTRACT Background Head and neck cancer (HNC) is a devastating diagnosis, with advanced‐stage disease leading to poorer outcomes. This qualitative study aimed to identify health system factors associated with stage of HNC diagnosis. Methods Qualitative semistructured interviews with HNC patients and clinicians were undertaken in two purposively ...
Grant Creaney +196 more
wiley +1 more source