Jurnal Kedokteran Hewan, 2017 The objective of this study was to identify the five different viral infections including avian influenza, Newcastle disease, avian reovirus, avian encephalomyelitis, and Marek’s disease in the runting-stunting syndrome outbreak in several commercial ...
Risza Hartawan +1 more
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An Overview on Marek’s Disease Virus Evolution and Evidence for Increased Virulence in Brazil
Brazilian Journal of Poultry Science, 2019 Marek’s disease virus (MDV) has been shown to be evolving to higher virulence. One of the genetic sites involved in virulence which enables such characterization is the 339-amino acid Meq protein encoding gene (meq).
ACD Torres +3 more
doaj +1 more source
Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays [PDF]
, 2010 Basic-region leucine-zipper transcription factors (bZIPs) contain a segment rich in basic amino acids that can bind DNA, followed by a leucine zipper that can interact with other leucine zippers to form coiled-coil homo- or heterodimers.
Acharya A. +69 more
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Updating of epidemiological and pathological features of Marek's disease in laying hens and broilers
Veterinární Medicína, 2023 Marek's disease (MD) is a huge problem for researchers due to the significant losses in bird flocks, but more importantly, the virus's mutagenic potential.
M Zeghdoudi +5 more
doaj +1 more source
Immunological basis of differences in disease resistance in the chicken [PDF]
, 2002 Genetic resistance to diseases is a multigenic trait governed mainly by the immune system and its interactions with many physiologic and environmental factors.
Gruys, E. +5 more
core +2 more sources
Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding. [PDF]
, 2015 Highly polymorphic major histocompatibility complex (MHC) molecules are at the heart of adaptive immune responses, playing crucial roles in many kinds of disease and in vaccination. We report that breadth of peptide presentation and level of cell surface
A Madrigal (7759361) +19 more
core +6 more sources
Metabolomic profiling of Marek’s disease virus infection in host cell based on untargeted LC-MS
Frontiers in Microbiology, 2023 Marek’s disease (MD) caused by Marek’s disease virus (MDV), poses a serious threat to the poultry industry by inducing neurological disease and malignant lymphoma in infected chickens.
Qingsen Wang +23 more
doaj +1 more source
The peptide motif of the single dominantly expressed class I molecule of the chicken MHC can explain the response to a molecular defined vaccine of infectious bursal disease virus (IBDV) [PDF]
, 2013 In contrast to typical mammals, the chicken MHC (the BF-BL region of the B locus) has strong genetic associations with resistance and susceptibility to infectious pathogens as well as responses to vaccines.
Butter, Colin +4 more
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, 2019 Marek’s disease (MD) is caused by an oncogenic alphaherpesvirus, a common lymphoproliferative inducing agent usually characterized by mononuclear cellular infiltrates, mostly T-cell lymphomas in various visceral organs and peripheral nerves. The genome is linear and made up of double-stranded DNA molecules of nearly 160–180 kb in size.
Asok Kumar Mariappan +4 more
openaire +2 more sources
Scientific Reports, 2017 Marek’s disease is a contagious lymphoproliferative disease of chickens and typical model of viral oncogenesis. Mapping changes or different states over the course of infection for both host and pathogen would provide important insights into dynamic host-
Jie Li +4 more
doaj +1 more source