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Marek’s Disease Virus Infection of Natural Killer Cells [PDF]
Microorganisms, 2019 Natural killer (NK) cells are key players in the innate immune response. They kill virus-infected cells and are crucial for the induction of adaptive immune responses. Marek's disease virus (MDV) is a highly contagious alphaherpesvirus that causes deadly
Luca D. Bertzbach +4 more
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Marek’s Disease Virus Virulence Genes Encode Circular RNAs [PDF]
Journal of Virology, 2022 Circular RNAs (circRNAs) were rediscovered in recent years both in physiological and pathological contexts, such as in cancer. Viral circRNAs are encoded by at least two human herpesviruses, the Epstein Barr virus and the Kaposi’s Sarcoma-associated ...
Alexis S Chasseur +9 more
semanticscholar +7 more sources
Pathology and Molecular Diagnosis of Marek’s Disease Virus in Chickens in Nigeria [PDF]
ScientificaMarek’s disease caused by Marek’s disease virus (MDV) serotype 1 is an economically important neoplastic disease of poultry. Diagnosis of this disease is usually based on clinical signs, postmortem lesions, and diagnostic tests like cytology ...
Olusegun Adesina Fagbohun +11 more
doaj +2 more sources
PLoS Biology, 2021 Viral diseases pose major threats to humans and other animals, including the billions of chickens that are an important food source as well as a public health concern due to zoonotic pathogens.
Samer Halabi +9 more
doaj +2 more sources
Amino acid insertion in the Meq protein of Marek’s disease virus, an avian oncogenic herpesvirus, accelerates tumorigenesis [PDF]
Microbiology SpectrumMarek’s disease virus (MDV) causes lymphomas (Marek’s disease) in chickens. Despite vaccination, MDV field strains exhibit increased virulence, and sporadic outbreaks are still reported.
Jumpei Sato +9 more
doaj +2 more sources
A Special Issue on Marek’s Disease Virus—The Editors’ View [PDF]
Microorganisms, 2023 Marek’s disease virus (MDV), an Alphaherpesvirus belonging to the genus Mardivirus, causes T cell lymphomas in chickens and remains one of the greatest threats to poultry production worldwide [...]
Benedikt B. Kaufer +2 more
doaj +2 more sources
Vaccines, 2021 Marek’s disease virus (MDV) is a highly contagious alphaherpesvirus that causes rapid onset lymphoma in chickens. Marek’s disease (MD) is effectively controlled using vaccination; however, MDV continues to break through vaccinal immunity, due to the ...
Yifei Liao +4 more
doaj +2 more sources
Marek's disease virus: from miasma to model
Nature Reviews Microbiology, 2006 Marek's disease virus (MDV) is an oncogenic herpesvirus that causes various clinical syndromes in its natural host, the chicken. MDV has long been of interest as a model organism, particularly with respect to the pathogenesis and immune control of virus-induced lymphoma in an easily accessible small-animal system.
N. Osterrieder +4 more
semanticscholar +4 more sources
Application of lentinan in suppression of Marek's disease virus infection [PDF]
Poultry ScienceMarek's disease virus (MDV) is an extremely widespread avian immunosuppressive virus. In recent years, many reports have shown that there are still cases of MDV infection and immunosuppression after immunization with the vaccine. Consequently, there is a
Qiming Gao +6 more
doaj +2 more sources
Overexpression of Interleukin-17 Modulates Responses to Marek’s Disease Virus Infection and Tumor Formation in Chickens [PDF]
VirusesMarek’s Disease Virus (MDV) is a highly contagious pathogen in chickens, resulting in immunosuppression and T-cell lymphomas. Understanding the role of host cytokines in MDV pathogenesis is crucial for developing effective interventions.
Nitish Boodhoo +4 more
doaj +2 more sources