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Latest Insights into Marek’s Disease Virus Pathogenesis and Tumorigenesis
Cancers, 2020 Marek’s disease virus (MDV) infects chickens and causes one of the most frequent cancers in animals. Over 100 years of research on this oncogenic alphaherpesvirus has led to a profound understanding of virus-induced tumor development.
L. D. Bertzbach +3 more
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Marek’s disease virus and skin interactions [PDF]
Veterinary Research, 2014 Marek's disease virus (MDV) is a highly contagious herpesvirus which induces immunosuppression and T-cell lymphoma in chicken. This virus still circulates in flocks despite forty years of vaccination, with important economical losses at the world level.
Couteaudier, Mathilde +1 more
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Occurrence of Marek’s disease in Poland on the basis of diagnostic examination in 2015–2018
Journal of Veterinary Research, 2020 Marek’s disease (MD) is a tumourous disease caused by Marek’s disease virus (MDV) and most commonly described in poultry. The aim of the study was to determine the occurrence of Marek’s disease virus infections in Poland and analyse clinical cases in the
Kozdruń Wojciech +5 more
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, 2019 Marek’s disease (MD) is caused by an oncogenic alphaherpesvirus, a common lymphoproliferative inducing agent usually characterized by mononuclear cellular infiltrates, mostly T-cell lymphomas in various visceral organs and peripheral nerves. The genome is linear and made up of double-stranded DNA molecules of nearly 160–180 kb in size.
Asok Kumar Mariappan +4 more
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PLoS Pathogens, 2021 Marek’s disease virus (MDV) is a potent oncogenic alphaherpesvirus that elicits a rapid onset of malignant T-cell lymphomas in chickens. Three MDV types, including GaHV-2 (MDV-1), GaHV-3 (MDV-2) and MeHV-1 (HVT), have been identified and all encode a US3
Yifei Liao +3 more
semanticscholar +1 more source
Marek’s disease in the holland white crested chickens [PDF]
Veterinarski Glasnik, 2016 Marek’s disease is a viral lymphoproliferative disease of poultry characterized by the creation of lymphoma in muscle, skin, eye or internal organs.
Spalević Ljiljana +5 more
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Animals, 2020 Marek’s disease is widely controlled by vaccination programs; however, chickens are not totally protected, especially immediately after the vaccination when a strong challenge could interfere with the effectiveness of vaccination in the absence of proper
Alessandro Stamilla +8 more
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MAREK'S DISEASE HERPES VIRUS: A CYTOMEGALOVIRUS? [PDF]
Proceedings of the National Academy of Sciences, 1969 The DNA of herpes viruses associated with Marek's disease of fowl contains 56-57 moles of guanine and cytosine per 100. The composition of its DNA and lack of infectiousness of cell-free preparations suggest that the herpes virus associated with Marek's disease belongs to the herpes virus group B which contains predominantly cytomegaloviruses.
L F, Lee +5 more
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Hayati Journal of Biosciences, 2016 There is an increasing trend to use molecular approaches to the study of Marek’s disease virus serotype 1 (MDV-1), the causative agent for the neoplastic syndrome of chickens known as Marek’s disease.
Risza Hartawan +1 more
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BMC Veterinary Research, 2018 Background Marek’s disease virus (MDV) resides in the genus Mardivirus in the family Herpesviridae. MDV is a highly contagious virus that can cause neurological lesions, lymphocytic proliferation, immune suppression, and death in avian species, including
Xue Lian +8 more
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