Results 31 to 40 of about 2,649 (156)

Marek’s Disease Virus Virulence Genes Encode Circular RNAs [PDF]

Journal of Virology, 2022
Circular RNAs (circRNAs) were rediscovered in recent years both in physiological and pathological contexts, such as in cancer. Viral circRNAs are encoded by at least two human herpesviruses, the Epstein Barr virus and the Kaposi’s Sarcoma-associated herpesvirus, both associated with the development of lymphoma.
Chasseur, Alexis, Trozzi, Gabrielle, Istasse, Céline, Petit, Astrid, Rasschaert, Perrine, Denesvre, Caroline, Kaufer, Benedikt, Bertzbach, Luca, Muylkens, Benoît, Coupeau, Damien   +9 more
openaire   +6 more sources

Marek's disease herpesvirus serotype 1 in broiler breeder and layer chickens in Malaysia [PDF]

Veterinary World, 2019
Aim: This study aimed to investigate the occurrence of Marek's disease (MD) in five poultry farms in Malaysia using postmortem examination, histopathology, and polymerase chain reaction (PCR).
Iryanti Othman, Erkihun Aklilu
doaj   +1 more source

Modeling Marek's disease virus transmission: A framework for evaluating the impact of farming practices and evolution

Epidemics, 2018
Marek's disease virus (MDV) is a pathogen of chickens whose control has twice been undermined by pathogen evolution. Disease ecology is believed to be the main driver of this evolution, yet mathematical models of MDV disease ecology have never been ...
David A. Kennedy, Patricia A. Dunn, Andrew F. Read   +2 more
doaj   +1 more source

Rapid, Sensitive, and Species-Specific Detection of Conventional and Recombinant Herpesvirus of Turkeys Vaccines Using Loop-Mediated Isothermal Amplification Coupled With a Lateral Flow Device Readout

Frontiers in Veterinary Science, 2022
Marek's disease, an economically important disease of chickens caused by virulent serotype 1 strains of the Mardivirus Marek's disease virus (MDV-1), is effectively controlled in the field by live attenuated vaccine viruses including herpesvirus of ...
Giulia Mescolini, Susan J. Baigent, Elena Catelli, Venugopal K. Nair   +3 more
doaj   +1 more source

A novel method for genome-wide profiling of dynamic host-pathogen interactions using 3′ end enriched RNA-seq

Scientific Reports, 2017
Marek’s disease is a contagious lymphoproliferative disease of chickens and typical model of viral oncogenesis. Mapping changes or different states over the course of infection for both host and pathogen would provide important insights into dynamic host-
Jie Li, Liangliang He, Yun Zhang, Chunyi Xue, Yongchang Cao   +4 more
doaj   +1 more source

An Overview on Marek’s Disease Virus Evolution and Evidence for Increased Virulence in Brazil

Brazilian Journal of Poultry Science, 2019
Marek’s disease virus (MDV) has been shown to be evolving to higher virulence. One of the genetic sites involved in virulence which enables such characterization is the 339-amino acid Meq protein encoding gene (meq).
ACD Torres, SY Marin, CS Costa, NRS Martins   +3 more
doaj   +1 more source

Deletion of the Viral Thymidine Kinase in a Meq-Deleted Recombinant Marek’s Disease Virus Reduces Lymphoid Atrophy but Is Less Protective

Microorganisms, 2021
Marek’s disease (MD) is a ubiquitous disease of domesticated chickens and its etiologic agent is the Gallid alphaherpesvirus 2 (GaHV-2), also known as Marek’s disease virus (MDV). MD is currently controlled by vaccination using live attenuated strains of
Steven J. Conrad, Eniope B. Oluwayinka, Mohammad Heidari, Jody K. Mays, John R. Dunn   +4 more
doaj   +1 more source

Protection against Marek's disease by a fowlpox virus recombinant expressing the glycoprotein B of Marek's disease virus [PDF]

Journal of Virology, 1992
Fowlpox virus (FPV) recombinants expressing the glycoprotein B and the phosphorylated protein (pp38) of the GA strain of Marek's disease virus (MDV) were assayed for their ability to protect chickens against challenge with virulent MDV. The recombinant FPV expressing the glycoprotein B gene elicited neutralizing antibodies against MDV, significantly ...
K, Nazerian, L F, Lee, N, Yanagida, R, Ogawa   +3 more
openaire   +2 more sources

Differential attenuation of Marek’s disease virus-induced tumours and late-Marek’s disease virus-induced immunosuppression

Journal of General Virology, 2018
Marek's disease virus (MDV) is a herpesvirus that induces lymphoma and a variety of non-neoplastic syndromes in chickens. Furthermore, very virulent plus (vv+) MDVs induce a form of immunosuppression (late-MDV-IS) that might involve both neoplastic and non-neoplastic mechanisms. The objective of this study was to evaluate whether the attenuation of MDV-
Nik Mohd Azmi, Nik Mohd Faiz, Cortes, Aneg L., Guy, James S., Reddy, Sanjay M., Gimeno, Isabel M.   +4 more
openaire   +2 more sources

PERCC1‐associated enteropathy: Diagnostic challenges and enteral autonomy achieved with teduglutide

JPGN Reports, EarlyView.
Abstract Congenital diarrheas and enteropathies (CODE) are rare inherited disorders characterized by early‐onset intractable diarrhea. Though progress has been made in elucidating the genetic basis of CODE, much remains to be discovered. Another challenge is the lack of curative therapies—treatment is primarily supportive including enteral and ...
Angela Tran, Vivien Nguyen, Phuong Huynh
wiley   +1 more source