Results 51 to 60 of about 486,062 (218)

Inhibition of DNA-Sensing Pathway by Marek's Disease Virus VP23 Protein through Suppression of Interferon Regulatory Factor 7 Activation

Journal of Virology, 2018
Despite widespread vaccination, Marek’s disease (MD) continues to pose major challenges for the poultry industry worldwide. MDV causes immunosuppression and deadly lymphomas in chickens, suggesting that this virus has developed a successful immune ...
Li Gao, Kai Li, Yu Zhang, Yongzhen Liu, Chang-jun Liu, Yanping Zhang, Yulong Gao, X. Qi, H. Cui, Yong-qiang Wang, Xiaomei Wang   +10 more
semanticscholar   +1 more source

Revisiting cellular immune response to oncogenic Marek’s disease virus: the rising of avian T-cell immunity

Cellular and Molecular Life Sciences, 2020
Marek’s disease virus (MDV) is a highly oncogenic alphaherpesvirus that causes deadly T-cell lymphomas and serves as a natural virus-induced tumor model in chickens.
Yi Yang, Maoli Dong, Xiaoli Hao, A. Qin, S. Shang   +4 more
semanticscholar   +1 more source

Late Marek's Disease in Adult Chickens Inoculated with Virulent Marek's Disease Virus

Journal of Veterinary Medical Science, 2010
Recently, excessive losses from Marek's disease (MD) have been noted in adult laying flocks over the age of 40 weeks. We defined these late outbreaks in adult chickens as "late MD", and experimentally reproduced the disease in adult SPF P2 line (50-week-old) or commercial line (74-week-old) chickens inoculated with a virulent strain of Marek's disease ...
Mitsutaka, Ikezawa, Masanobu, Goryo, Jun, Sasaki, Mohie, Haridy, Kosuke, Okada   +4 more
openaire   +3 more sources

New Advances of Degradable Magnesium‐Based Metal Biomaterials in the Field of Orthopedics

Rare Metals, EarlyView.
ABSTRACT Based on their outstanding biomechanical properties and superior osteogenic activity, magnesium (Mg) and its alloys have been extensively investigated for their biocompatibility and therapeutic efficacy in treating fractures and bone defects.
Jia‐Nan Yu, Shao‐Sheng Jia, Rong‐Bang Sun, Tong Zhang, Ling‐Chuang Bai, Di Mei, Shi‐Jie Zhu, Lan Chen, Shao‐Kang Guan   +8 more
wiley   +1 more source

Diverse uses of feathers with emphasis on diagnosis of avian viral infections and vaccine virus monitoring

Brazilian Journal of Poultry Science, 2009
The large amounts of feathers produced by the poultry industry, that is considered as a waste was explored for possible uses in various industries, such as meals for animals, biofuels, biodegradable plastic materials, combating water pollution and more ...
I Davidson
doaj   +1 more source

Silent pressure: Unveiling spinal lymphoma in horses and its parallels to other species

Equine Veterinary Education, EarlyView.
Summary Though the nervous system is an uncommon location for lymphoma, the disease should remain a differential diagnosis in some cases of ataxia in equids. Diagnosis of lymphoma can be challenging, although a combination of cytology, histopathology and immunophenotyping can aid in definitive diagnosis and therefore more accurately guide treatment and
H. E. Taylor, D. Luethy
wiley   +1 more source

MOLECULAR CHARACTERIZATION AND HISTOPATHOLOGICAL ANALYSIS OF AVIAN RETICULOENDOTHELIOSIS VIRUS FROM GUINEA FOWL IN TAMIL NADU [PDF]

Exploratory Animal and Medical Research
The present study was carried out to detect the causative agent of sudden death in guinea fowl f lock maintained at organized poultry farm, Orathanadu. On post mortem examination, liver was enlarged and revealed multiple grayish areas.
P. Ponnusamy
doaj   +1 more source

Atrophy of primary lymphoid organs induced by Marek’s disease virus during early infection is associated with increased apoptosis, inhibition of cell proliferation and a severe B-lymphopenia

Veterinary Research, 2018
Marek’s disease is a multi-faceted highly contagious disease affecting chickens caused by the Marek’s disease alphaherpesvirus (MDV). MDV early infection induces a transient immunosuppression, which is associated with thymus and bursa of Fabricius ...
C. Berthault, T. Larcher, S. Härtle, J. Vautherot, Laetitia Trapp-Fragnet, C. Denesvre   +5 more
semanticscholar   +1 more source

Plasma proteomic profiling and molecular clustering reveal immune‐defined prognostic subtypes in lung adenocarcinoma

International Journal of Cancer, Volume 158, Issue 4, Page 858-865, 15 February 2026.
What's new? Lung adenocarcinoma shows considerable heterogeneity in disease progression and therapeutic response. Here, the authors analyzed tumor samples through proteomic profiling and applied network‐based clustering. They identified two distinct patient groups with different demographic, clinical, and molecular characteristics.
Ujjwal Neogi, Anoop T. Ambikan, Kati Turkowski, Marc A. Schneider, Vanessa M. Beutgen, Johannes Graumann, Hauke Winter, Marek Bartkuhn, Werner Seeger, Soni S. Pullamsetti, Rajkumar Savai   +10 more
wiley   +1 more source

Efficient Mutagenesis of Marek’s Disease Virus-Encoded microRNAs Using a CRISPR/Cas9-Based Gene Editing System

Viruses, 2020
The virus-encoded microRNAs (miRNAs) have been demonstrated to have important regulatory roles in herpesvirus biology, including virus replication, latency, pathogenesis and/or tumorigenesis.
Jun Luo, M. Teng, Xusheng Zai, N. Tang, Yaoyao Zhang, Ahmedali S. Mandviwala, V. R. Reddy, S. Baigent, Yongxiu Yao, V. Nair   +9 more
semanticscholar   +1 more source