Results 81 to 90 of about 486,062 (218)

Marek’s Disease Virus (Gallid alphaherpesvirus 2)-Encoded miR-M2-5p Simultaneously Promotes Cell Proliferation and Suppresses Apoptosis Through RBM24 and MYOD1-Mediated Signaling Pathways

Frontiers in Microbiology, 2020
MicroRNAs (miRNAs) have been demonstrated for their involvement in virus biology and pathogenesis, including functioning as key determinants of virally-induced cancers.
Zhi-Jian Zhu, Zhi-Jian Zhu, Zhi-Jian Zhu, Man Teng, Man Teng, Hui-Zhen Li, Hui-Zhen Li, Hui-Zhen Li, Lu-Ping Zheng, Lu-Ping Zheng, Jin-Ling Liu, Jin-Ling Liu, Shu-Jun Chai, Shu-Jun Chai, Yong-Xiu Yao, Venugopal Nair, Gai-Ping Zhang, Gai-Ping Zhang, Jun Luo, Jun Luo, Jun Luo   +20 more
doaj   +1 more source

Current understanding of lymphoproliferative disease virus in wild turkeys

Wildlife Society Bulletin, Volume 49, Issue S1, December 2025.
Lymphoproliferative disease virus (LPDV) is a retrovirus that can cause a spectrum of disease in wild turkeys (Meleagris gallopavo), from subclinical infection to lymphoid tumors. We reviewed the literature to summarize our current understanding of LPDV, including disease presentation, surveillance, impact on fitness, spatiotemporal distribution, and ...
Chloe C. Goodwin, Andrew B. Allison, Mark G. Ruder, Justin D. Brown, Michael J. Chamberlain, Melanie R. Kunkel, Kevin D. Niedringhaus, Alisia A. W. Weyna, Charlie S. Bahnson, Elizabeth L. Elsmo, M. Kevin Keel, Heather Fenton, Kayla G. Adcock, Rebecca L. Poulson, Nicole M. Nemeth   +14 more
wiley   +1 more source

A novel protein-coding ORF72.2 gene was identified from Marek's disease virus strain CVI988

Virology Journal, 2010
Marek's disease is a highly contagious disease of poultry characterized by rapid-on set of T-cell lymphomas, which is caused by Marek's disease virus (MDV), but its pathogenic mechanism is still not very clear.
Liu Ping, Zou Nianli, Lin Yan, Shi Min, Zhao Yang, Tian Mingxing, Wen Xintian, Cao Sanjie, Huang Yong   +8 more
doaj   +1 more source

Viral haemorrhagic septicaemia virus, infectious haematopoietic necrosis virus and HPR‐deleted infectious salmon anaemia virus – Risk of introduction in free areas through fertilised eggs and gametes

EFSA Journal, Volume 23, Issue 12, December 2025.
Abstract EFSA assessed the risk of introducing viral haemorrhagic septicaemia virus (VHSV), infectious haematopoietic necrosis virus (IHNV) and highly polymorphic region‐deleted infectious salmon anaemia virus (HPR‐deleted ISAV) into free areas through movement of fertilised eggs and gametes.
EFSA Panel on Animal Health and Welfare (AHAW), Søren Saxmose Nielsen, Julio Alvarez, Anette Boklund, Sabine Dippel, Jordi Figuerola, Mette S. Herskin, Virginie Michel, Miguel Angel Miranda Chueca, Eleonora Nannoni, Romolo Nonno, Anja B. Riber, Karl Ståhl, Jan Arend Stegeman, Hans‐Hermann Thulke, Frank Tuyttens, Christoph Winckler, Debes Hammershaimb Christiansen, Niels Jørgen Olesen, Espen Rimstad, Anna Toffan, Niccolò Vendramin, Stella Papaleo, Ludovica Preite, Francesca Baldinelli, Fernanda Dórea   +25 more
wiley   +1 more source

Co-Infection with Marek’s Disease Virus and Reticuloendotheliosis Virus Increases Illness Severity and Reduces Marek’s Disease Vaccine Efficacy

Viruses, 2017
Marek’s disease virus (MDV) and reticuloendotheliosis virus (REV) cause Marek’s disease (MD) and reticuloendotheliosis (RE), respectively. Co-infection with MDV and REV is common in chickens, causing serious losses to the poultry industry.
Guo-rong Sun, Yan-ping Zhang, Lin-yi Zhou, Hong-chao Lv, Feng Zhang, Kai Li, Yu-long Gao, X. Qi, Hong-yu Cui, Yong-qiang Wang, Li Gao, Q. Pan, Xiaomei Wang, Chang-jun Liu   +13 more
semanticscholar   +1 more source

Brain‐Wide Patterns of CRF Receptor 1 Expression in the Transgenic CRFR1‐Cre‐2a‐tdTom Rat

Journal of Comparative Neurology, Volume 533, Issue 11, November 2025.
In this article, we provide an extensive neuroanatomical characterization of a recently generated CRFR1‐Cre‐2A‐tdTomato rat. We show that Cre and tdTomato are expressed in a pattern that closely aligns with previously reported CRFR1 expression patterns.
Douglas S. Engelke, Lierni Ugartemendia, Jonathan Tao, Shivakumar Rajamanikam, Fabricio H. Do Monte, Nicholas J. Justice   +5 more
wiley   +1 more source

Use o fDulbecco's modified eagle's medium DMEM/F12 HAM for Marek's disease virus cultivation in chicken embryo fibroblasts

Ветеринария сегодня, 2018
The opportunity of using Dulbecco's Modified Eagle's Medium DMEM/F12 Ham for Marek's disease cultivation in chicken embryo fibroblasts was studied. It was determined that if appropriate virus cultivation parameters are chosen the abovementioned medium ...
Ye. Yu. Khanyukova, M. A. Shustova, H. Ye. Kamalova   +2 more
doaj  

Protection study of the Labio-Marek vaccine against the JM strain challenge in SPF chickens

VacciMonitor, 2014
Marek's disease is a lymphomatous and neuropathic disease of the domestic chickens caused by herpesvirus. Currently the acute form of the disease, with extended visceral lymphomas, is the most common with an incidence of 10-30%.
Mayelin Paneque-Sayas, Digna Contreras-González, Anniet Fresneda, Gladys Proenza, Tania Irene Tabares- Beltrán, Eloy Diaz-Fernández   +5 more
doaj  

Marek’s Disease Virus Activates the PI3K/Akt Pathway Through Interaction of Its Protein Meq With the P85 Subunit of PI3K to Promote Viral Replication

Frontiers in Microbiology, 2018
It is known that viruses can active the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway in host cells to support cell survival and viral replication; however, the role of PI3K/Akt signaling in the pathogenic mechanisms induced by Marek’s ...
Huimin Li, Jiaojiao Zhu, Minyi He, Qiong Luo, Fan-Rui Liu, Ruiai Chen   +5 more
semanticscholar   +1 more source

Unraveling the role of γδ T cells in the pathogenesis of an oncogenic avian herpesvirus

mBio
Marek’s disease virus (MDV) is an oncogenic alphaherpesvirus that causes deadly lymphomas in chickens. In chickens, up to 50% of all peripheral T cells are gamma delta (γδ) T cells.
Mohammad A. Sabsabi, Ahmed Kheimar, Yu You, Dominik von La Roche, Sonja Härtle, Thomas W. Göbel, Theresa von Heyl, Benjamin Schusser, Benedikt B. Kaufer   +8 more
doaj   +1 more source