Results 121 to 130 of about 21,237,081 (159)

Maresin-like 1 Ameliorates Neuropathology of Alzheimer’s Disease in Brains of a Transgenic Mouse Model [PDF]

(1) Background: Impeded resolution of inflammation contributes substantially to the pathogenesis of Alzheimer’s disease (AD); consequently, resolving inflammation is pivotal to the amelioration of AD pathology.
Lien, Nathan, Song Hong, Nathan Lien, Walter J. Lukiw, Masoud, Abdul-Razak, Yuhai Zhao, Yan Lu, Shanchun Su, Su, Shanchun, Lukiw, Walter J, Zhao, Yuhai, Lu, Yan, Yuichi Kobayashi, Abdul-Razak Masoud, Shrivastava, Pallavi, Kobayashi, Yuichi, Pallavi Shrivastava, Hong, Song   +17 more
core   +2 more sources

The specialized pro-resolving lipid mediator maresin 1 protects hepatocytes from lipotoxic and hypoxia-induced endoplasmic reticulum stress. [PDF]

Endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR) are hallmarks of nonalcoholic fatty liver disease (NAFLD), which is the hepatic manifestation of the metabolic syndrome associated with obesity.
Rius, Bibiana, Titos Rodríguez, Esther, Casulleras, Mireia, Duran Güell, Marta, Alcaraz-Quiles, José, Lopategi, Aritz, Flores Costa, Roger, Clària i Enrich, Joan, López-Vicario, Cristina, Lozano, Juanjo   +9 more
core  

Resolution of post-lung transplant ischemia-reperfusion injury is modulated via Resolvin D1-FPR2 and Maresin 1-LGR6 signaling. [PDF]

J Heart Lung Transplant, 2023
Leroy V, Cai J, Tu Z, McQuiston A, Sharma S, Emtiazjoo A, Atkinson C, Upchurch GR, Sharma AK.   +8 more
europepmc   +1 more source

The pro-resolving lipid mediator Maresin 1 ameliorates pain responses and neuroinflammation in the spared nerve injury-induced neuropathic pain: A study in male and female mice. [PDF]

PLoS One, 2023
Teixeira-Santos L, Martins S, Sousa T, Albino-Teixeira A, Pinho D.   +4 more
europepmc   +1 more source

Maresin 1 Alleviates Diabetic Kidney Disease via LGR6-Mediated cAMP-SOD2-ROS Pathway. [PDF]

Oxid Med Cell Longev, 2022
Li X, Xu B, Wu J, Pu Y, Wan S, Zeng Y, Wang M, Luo L, Zhang F, Jiang Z, Xu Y.   +10 more
europepmc   +1 more source

Signaling Pathways Used by the Specialized Pro-Resolving Mediator Maresin 2 Regulate Goblet Cell Function: Comparison with Maresin 1. [PDF]

Int J Mol Sci, 2022
Olsen MV, Lyngstadaas AV, Bair JA, Hodges RR, Utheim TP, Serhan CN, Dartt DA.   +6 more
europepmc   +1 more source

Maresin-1 Alleviates Sepsis-Induced Liver Injury by Regulating Apoptosis and Autophagy via Activation of the PI3K/Akt Signaling Pathway in Mice. [PDF]

Curr Issues Mol Biol
Wang H, Sun M, Fan H.
europepmc   +1 more source

Maresin-1 Prevents Liver Fibrosis by Targeting Nrf2 and NF-κB, Reducing Oxidative Stress and Inflammation. [PDF]

Cells, 2021
Rodríguez MJ, Sabaj M, Tolosa G, Herrera Vielma F, Zúñiga MJ, González DR, Zúñiga-Hernández J.   +6 more
europepmc   +1 more source

lk27 [PDF]

1, 1
core  

Maresin 1 intervention reverses experimental pulmonary arterial hypertension in mice [PDF]

British Journal of Pharmacology, 2022
Background and PurposePulmonary arterial hypertension (PAH) is a pulmonary vasculature obstructive disease that leads to right heart failure and death. Maresin 1 is an endogenous lipid mediator known to promote inflammation resolution. However, the effect of Maresin 1 on PAH remains unclear.Experimental ApproachThe serum Maresin 1 concentration was ...
Hui Li, Haijian Cai, Mengsi Cai
exaly   +5 more sources