Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain
Self‐resolving inflammatory exudates and lipid mediator metabolomics recently uncovered a new family of potent anti‐inflammatory and proresolving mediators biosynthesized by macrophages (MΦs), denoted maresins. Here we determined that maresin 1 (MaR1) produced by human MΦs from endogenous docosahexaenoic acid (DHA) matched ...
Charles N, Serhan +8 more
openaire +3 more sources
Akut inmeli hastalarda Maresin-1'in inflamatuvar süreçlerle ilişkisi [PDF]
Giriş ve Amaç: İnme, tüm dünyada ikincil ölüm nedeni olup, özellikle gelişmekte olan ülkelerde inme sonrası meydana gelen fonksiyonal kayıpların tedavileri sağlık harcamalarında önemli bir paya sahiptir.
El Moustafa, Houssein
core
Resolvin E1 and maresin 1 restore senescence-induced disruption of human periodontal ligament fibroblast function [PDF]
BackgroundAging impairs the mechanisms that regulate inflammation, resulting in low-level chronic inflammation even in the absence of infection and increasing the risk of developing age-related illnesses.
Kantarcı, Alpdoğan +2 more
core +1 more source
Does exercise enhance maresin-1 production? A new direction in metabolic anti-inflammatory research [PDF]
Obesity is a major global health challenge characterized by chronic low-grade inflammation and metabolic dysfunction. Among lipid-derived mediators involved in inflammation resolution, maresin-1 (MaR1)—a specialized pro-resolving mediator derived from ...
Mehran Alipour +6 more
doaj +1 more source
Maresin 1 attenuates NAFLD by suppression of endoplasmic reticulum stress via AMPK–SERCA2b pathway [PDF]
Maresin 1 (MAR1), which is derived from docosahexaenoic acid biosynthesized by macrophages, has been reported to improve insulin resistance. Recently, it has been documented that MAR1 could ameliorate inflammation and insulin resistance in obese mice ...
Ji Hoon Jeong +7 more
core +1 more source
Maresin 1 Ameliorates Lung Ischemia/Reperfusion Injury by Suppressing Oxidative Stress via Activation of the Nrf-2-Mediated HO-1 Signaling Pathway [PDF]
Lung ischemia/reperfusion (I/R) injury occurs in various clinical conditions and heavily damaged lung function. Oxidative stress reaction and antioxidant enzymes play a pivotal role in the etiopathogenesis of lung I/R injury.
Quanchao Sun +3 more
core +1 more source
The effect of cardiopulmonary bypass on Maresin-1 levels and implications for cardiac function
Aim: Cardiopulmonary bypass (CPB) surgery causes changes in biomarkers associated with inflammatory responses and cardiac stress. Maresin-1 is a novel lipid mediator involved in inflammation resolution, and its role in cardiac function and its prognostic value postoperatively have not yet been sufficiently investigated.
Bişar Amaç +2 more
openaire +1 more source
PES ve PEG da TGF beta sinyal yolağı ile serum maresin düzeyleri arasındaki ilişkinin araştırılması [PDF]
PES ve PEG de maresin düzeyleri düşmektedir. Etiyolojide rolü olabilir:
Fatma Tuğçe Yavuz Öztürk
core
Synthesis of maresin 1 and (7S)-isomer
identifier:oai:t2r2.star.titech.ac.jp ...
openaire

