Results 21 to 30 of about 1,753 (134)

Circulating Maresin-1 and cartilage remodeling biomarkers in rheumatoid arthritis and osteoarthritis [PDF]

Scientific Reports
Rheumatoid arthritis (RA) and osteoarthritis (OA) are prevalent chronic joint diseases characterized by persistent inflammation, progressive cartilage degeneration, and impaired tissue repair mechanisms.
Omer Esmez, Gulnihal Deniz, Zubeyde Ercan, Secil Yılmaz, Meryem Sedef Dogru, Ahmet Karatas   +5 more
doaj   +2 more sources

Maresin 1 activates brown adipose tissue and promotes browning of white adipose tissue in mice [PDF]

Molecular Metabolism, 2023
Objective: Maresin 1 (MaR1) is a docosahexaenoic acid-derived proresolving lipid mediator with insulin-sensitizing and anti-steatosis properties. Here, we aim to unravel MaR1 actions on brown adipose tissue (BAT) activation and white adipose tissue (WAT)
Laura M. Laiglesia, Xavier Escoté, Neira Sáinz, Elisa Felix-Soriano, Eva Santamaría, María Collantes, Marta Fernández-Galilea, Ignacio Colón-Mesa, Leyre Martínez-Fernández, Tania Quesada-López, Sergio Quesada-Vázquez, Carlos Rodríguez-Ortigosa, José M. Arbones-Mainar, Ángela M. Valverde, J Alfredo Martínez, Jesmond Dalli, Laura Herrero, Silvia Lorente-Cebrián, Francesc Villarroya, María J. Moreno-Aliaga   +19 more
doaj   +2 more sources

Decreased Plasma Maresin 1 Concentration Is Associated with Diabetic Foot Ulcer [PDF]

Mediators of Inflammation, 2020
Aims. To assess the maresin 1 (MaR1) contents in type 2 diabetic patients with or without diabetic foot ulcer and to analyze the association of MaR1 concentrations with several metabolism-related parameters. Methods.
Tian Miao, Bangliang Huang, Niexia He, Lihua Sun, Guangsheng Du, Xiaoli Gong, Yong Xu, Yi Zheng, Hongting Zheng, Hua Qu   +9 more
doaj   +3 more sources

Specialized pro-resolving mediator Maresin 1 attenuates pain in a mouse model of osteoarthritis [PDF]

Osteoarthritis and Cartilage
We test whether the specialized pro-resolving molecule Maresin 1 (MaR1) attenuates nociceptive behaviors in mice with osteoarthritis-like pain.Osteoarthritis (OA)-like pain behavior was induced by intra-articular injection of monosodium iodoacetate (MIA) and treated with MaR1 (N=6) or vehicle (N=5) by intraperitoneal injection 8 weeks after injury ...
Shyni Varghese, Yuan-Wen Lee, Anna Gilpin   +2 more
exaly   +4 more sources

Maresin 1 Exerts a Tissue-Specific Regulation of Adipo-Hepato-Myokines in Diet-Induced Obese Mice and Modulates Adipokine Expression in Cultured Human Adipocytes in Basal and Inflammatory Conditions [PDF]

Biomolecules, 2023
This study analyses the effects of Maresin 1 (MaR1), a docosahexaenoic acid (DHA)-derived specialized proresolving lipid mediator with anti-inflammatory and insulin-sensitizing actions, on the expression of adipokines, including adiponectin, leptin ...
Leyre Martínez-Fernández, Miguel Burgos, Neira Sáinz, Laura M. Laiglesia, José Miguel Arbones-Mainar, Pedro González-Muniesa, María J. Moreno-Aliaga   +6 more
doaj   +2 more sources

Plasma and aqueous humor levels of Maresin-1 in patients with diabetic retinopathy [PDF]

Scientific Reports
The aim of this study was to evaluate plasma and aqueous Maresin-1 (MaR1) levels in patients with diabetic retinopathy (DR) and to examine the ability of these levels to distinguish proliferative diabetic retinopathy.
Sabiha Güngör Kobat, Fatih Cem Gül, Fatih Çelik, Seda Liman Uzun, Fatma Savur, Kader Kasar, Sara Koylu Güngör, Mehmet Balbaba, Süleyman Aydın   +8 more
doaj   +2 more sources

Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis [PDF]

Mediators of Inflammation, 2016
Sepsis, frequently caused by infection of bacteria, is considered as an uncontrollable systematic inflammation response syndrome (SIRS). Maresin 1 (Mar1) is a new proresolving mediator with potent anti-inflammatory effect in several animal models ...
Ruidong Li, Yaxin Wang, Zhijun Ma, Muyuan Ma, Di Wang, Gengchen Xie, Yuping Yin, Peng Zhang, Kaixiong Tao   +8 more
doaj   +3 more sources

Serum Resolvin D1 and Maresin 1 Levels During Migraine Attacks and the Interictal Period: A Paired Analysis in Emergency Department Patients [PDF]

Biomedicines
Background/Objectives: Neurogenic inflammation plays a key role in migraine pathophysiology. This study aimed to evaluate serum Resolvin D1 (RvD1) and Maresin 1 (MaR1) levels during acute migraine attacks and in the interictal period in the same patients,
Miraç Koç, Özge Özen Gökmuharremoğlu, Neslihan Cihan Çalışgan   +2 more
doaj   +2 more sources

Maresin-1 Attenuates Sepsis-Associated Acute Kidney Injury via Suppressing Inflammation, Endoplasmic Reticulum Stress and Pyroptosis by Activating the AMPK/SIRT3 Pathway [PDF]

Journal of Inflammation Research
Miaomiao Sun,1– 3,* Fuquan Wang,1– 3,* Haopeng Li,1– 3 Mengyu Li,1– 3 Yu Wang,1– 3 Chenchen Wang,1– 3 Yan Zhang,1– 3 Dingyu Zhang,1– 4 Jianhua Li,5 Shanglong Yao1– 3 1Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong ...
Sun M, Wang F, Li H, Li M, Wang Y, Wang C, Zhang Y, Zhang D, Li J, Yao S   +9 more
doaj   +2 more sources

Maresin 1 Improves Cognitive Decline and Ameliorates Inflammation in a Mouse Model of Alzheimer’s Disease

Frontiers in Cellular Neuroscience, 2019
Alzheimer’s disease (AD) is one of the most common neurodegenerative disease. Accumulating evidences suggest an active role of inflammation in the pathogenesis of AD.
Jiachun Feng, Mingqin Zhu, Zhu Mingqin   +2 more
exaly   +3 more sources