Results 41 to 50 of about 1,753 (134)
Southern Clinics of Istanbul Eurasia, 2020 INTRODUCTION[|]The purpose of this study is to examine the protective effects of maresin 1 on testicular injury induced by ischemia reperfusion. [¤]METHODS[|]24 Sprague-Dawley male rats were divided into 3 groups. The groups are planned as follows; sham,
Ayhan Tanyeli +6 more
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Maresin biosynthesis and identification of maresin 2, a new anti-inflammatory and pro-resolving mediator from human macrophages. [PDF]
PLoS ONE, 2014 Maresins are a new family of anti-inflammatory and pro-resolving lipid mediators biosynthesized from docosahexaenoic acid (DHA) by macrophages. Here we identified a novel pro-resolving product, 13R,14S-dihydroxy-docosahexaenoic acid (13R,14S-diHDHA ...
Bin Deng +6 more
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Maresin 1 attenuates neuroinflammation in a mouse model of perioperative neurocognitive disorders [PDF]
British Journal of Anaesthesia, 2019 Resolution of inflammation is an active and dynamic process after surgery. Maresin 1 (MaR1) is one of a growing number of specialised pro-resolving lipids biosynthesised by macrophages that regulates acute inflammation. We investigated the effects of MaR1 on postoperative neuroinflammation, macrophage activity, and cognitive function in mice.Adult male
Yang, T. +12 more
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Mediators of Inflammation, 2017 Background. Inflammation and fibrosis are the important pathophysiologic processes in diabetic nephropathy (DN). Maresin 1 is a potential anti-inflammatory lipid mediator, which has displayed powerful proresolving activities. Aim.
Shi Tang +7 more
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Maresin 1 resolves aged‐associated macrophage inflammation to improve bone regeneration [PDF]
The FASEB Journal, 2020 Abstract Inflammaging is associated with poor tissue regeneration observed in advanced age. Specifically, protracted inflammation after acute injury has been associated with decreased bone fracture healing and increased rates of nonunion in elderly patients.
Huang, Rong +3 more
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Mediators of Inflammation, 2015 In the trigeminal system, disruption of acute resolution processing may lead to uncontrolled inflammation and chronic pain associated with the temporomandibular joint (TMJ). Currently, there are no effective treatments for TMJ pain. Recently, it has been
Chul-Kyu Park
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Cells, 2022 An interconnection between tissue inflammation and regeneration has been established through the regulation of defense and repair mechanisms within diseased dental tissue triggered by the release of immune-resolvent mediators. To better our understanding
Shahd AlZahrani +4 more
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Maresin 1 induces a novel pro‐resolving phenotype in human platelets [PDF]
Journal of Thrombosis and Haemostasis, 2017 Essentials Specialized proresolving mediators (SPMs) promote the resolution of inflammation. This study sought to investigate the effects of SPMs on human platelet function. The SPM, Maresin 1, enhanced hemostatic, but suppressed inflammatory functions of platelets.
K L, Lannan +3 more
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Maresin 1 protects the liver against ischemia/reperfusion injury via the ALXR/Akt signaling pathway
Molecular Medicine, 2021 Background Hepatic ischemia/reperfusion (I/R) injury can be a major complication following liver surgery contributing to post-operative liver dysfunction. Maresin 1 (MaR1), a pro-resolving lipid mediator, has been shown to suppress I/R injury.
Da Tang +7 more
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Resolving Lipid Mediators Maresin 1 and Resolvin D2 Prevent Atheroprogression in Mice [PDF]
Circulation Research, 2016 Rationale: Atheroprogression is a consequence of nonresolved inflammation, and currently a comprehensive overview of the mechanisms preventing resolution is missing. However, in acute inflammation, resolution is known to be orchestrated by a switch from inflammatory to resolving lipid mediators ...
Viola, Joana R. +13 more
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