Inflammation is the most important element in the pathogenesis of major human diseases. It determines the fundamental value of anti-inflammatory therapy in the modern concept of targeted pathogenetic treatment.
A. E. Karateev, T. L. Aleinikova
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Incorporation of n-3 PUFA and γ-linolenic acid in blood lipids and red blood cell lipids together with their influence on disease activity in patients with chronic inflammatory arthritis - a randomized controlled human intervention trial [PDF]
Background and aim Marine n-3 fatty acids and γ-linolenic acid both have anti-inflammatory effects and may be useful to help treat inflammatory diseases.
Springer Monika +5 more
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Eicosanoids in skin inflammation. [PDF]
NoEicosanoids play an integral part in homeostatic mechanisms related to skin health and structural integrity. They also mediate inflammatory events developed in response to environmental factors, such as exposure to ultraviolet radiation, and ...
Agarwal +139 more
core +1 more source
Low-dose pro-resolving mediators temporally reset the resolution response to microbial inflammation
Background Specialized pro-resolving mediators (SPMs) promote resolution of inflammation, clear infections and stimulate tissue regeneration. These include resolvins, protectins, and maresins.
Charles N. Serhan +2 more
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N-3 Polyunsaturated Fatty Acids and the Resolution of Neuroinflammation
In the past few decades, as a result of their anti-inflammatory properties, n-3 long chain polyunsaturated fatty acids (n-3 LC-PUFAs), have gained greater importance in the regulation of inflammation, especially in the central nervous system (in this ...
Corinne Joffre +6 more
doaj +1 more source
Inhibitory effects of aspirin-triggered resolvin D1 on spinal nociceptive processing in rat pain models [PDF]
Background: Harnessing the actions of the resolvin pathways has the potential for the treatment of a wide range of conditions associated with overt inflammatory signalling.
Bennett, Andrew +4 more
core +5 more sources
Pro-Resolving Mediators in Regulating and Conferring Macrophage Function
Macrophages are central in coordinating the host response to both sterile and infective insults. Clearance of apoptotic cells and cellular debris is a key biological action preformed by macrophages that paves the way to the resolution of local ...
Jesmond Dalli, Charles N. Serhan
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Macrophages in wound healing: activation and plasticity. [PDF]
Macrophages are critically involved in wound healing, from dampening inflammation to clearing cell debris and coordinating tissue repair. Within the wound, the complexity of macrophage function is increasingly recognized, with adverse outcomes when ...
Kim, Sang Yong, Nair, Meera G
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Effects of n-3 polyunsaturated fatty acids on cardiac ion channels [PDF]
This Document is Protected by copyright and was first published by Frontiers. All rights reserved. it is reproduced with permissionDietary n-3 polyunsaturated fatty acids (PUFAs) have been reported to exhibit antiarrhythmic properties, and these effects ...
De La Cruz, Alicia +5 more
core +3 more sources
Novos mediadores locais da inflamação : proctetinas e resolvinas [PDF]
Dissertação para obtenção do grau de Mestre no Instituto Superior de Ciências da Saúde Egas MonizDiariamente o nosso corpo está sujeito a danos físicos ou infeções por microrganismos exógenos, este responde desencadeando uma resposta inflamatória, que ...
Figueiredo, João Filipe Rodrigues
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