Results 81 to 90 of about 3,920 (194)
Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions
MedComm, Volume 7, Issue 7, July 2026.Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An +4 more
wiley +1 more source
Pulmonary Circulation, Volume 16, Issue 3, July 2026.ABSTRACT Methamphetamine‐associated pulmonary arterial hypertension (Meth‐APAH) is an increasingly recognized cause of pulmonary arterial hypertension (PAH) and is associated with worse outcomes than idiopathic PAH (IPAH). Although both share histopathologic features of pulmonary vascular remodeling, the molecular basis for their clinical divergence ...
Hannah K. Robertson +7 more
wiley +1 more source
Potential benefits and risks of omega-3 fatty acids supplementation to patients with COVID-19
Free Radical Biology & Medicine, 2020 Studies have shown that infection, excessive coagulation, cytokine storm, leukopenia, lymphopenia, hypoxemia and oxidative stress have also been observed in critically ill Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) patients in addition ...
M. Rogero +7 more
semanticscholar +1 more source
Frontiers in Immunology, 2013 Inflammation, in conjunction with leukocytes, plays a key role in most acute kidney injury (AKI). Non-resolving renal inflammation leads to fibrosis and chronic renal failure.
Song eHong, Yan eLu
doaj +1 more source
Advanced Science, Volume 13, Issue 34, 19 June 2026.ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu +15 more
wiley +1 more source
Frontiers in Pharmacology, 2016 The omega-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are precursors to immune regulatory and specialized pro-resolving mediators (SPM) of inflammation termed resolvins, maresins, and protections.
Ellen L Mozurkewich +8 more
doaj +1 more source
Significance of long chain polyunsaturated fatty acids in human health
Clinical and Translational Medicine, 2017 In the last decades, the development of new technologies applied to lipidomics has revitalized the analysis of lipid profile alterations and the understanding of the underlying molecular mechanisms of lipid metabolism, together with their involvement in ...
R. Zárate +4 more
semanticscholar +1 more source
Low-dose pro-resolving mediators temporally reset the resolution response to microbial inflammation
Molecular MedicineBackground Specialized pro-resolving mediators (SPMs) promote resolution of inflammation, clear infections and stimulate tissue regeneration. These include resolvins, protectins, and maresins.
Charles N. Serhan +2 more
doaj +1 more source
Современная ревматология, 2016 Inflammation is the most important element in the pathogenesis of major human diseases. It determines the fundamental value of anti-inflammatory therapy in the modern concept of targeted pathogenetic treatment.
A. E. Karateev, T. L. Aleinikova
doaj +1 more source
NutrientsOmega-3 polyunsaturated fatty acids (n-3 PUFAs) are known to help resolve inflammation through generation of anti-inflammatory eicosanoids and specialized pro-resolving mediators, including resolvins, protectins, and maresins.
Donia Jerab +7 more
semanticscholar +1 more source