Results 61 to 70 of about 3,920 (194)
Frontiers in Immunology, 2023 Sjögren’s syndrome is a chronic inflammatory autoimmune disease characterized by diminished secretory function of the exocrine glands. Although extensive investigation has been done to understand Sjögren’s syndrome, the causes of the disease are as yet ...
Harim T. dos Santos +11 more
doaj +1 more source
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.Tirzepatide and SGLT2 inhibitors act through distinct but complementary mechanisms in obesity‐related HFpEF: tirzepatide targets adiposity, inflammation, and insulin resistance, while SGLT2 inhibitors improve decongestion, myocardial energetics, and cardiac remodeling.
Zakariye Isak Mohamed +8 more
wiley +1 more source
Advances in Our Understanding of Oxylipins Derived from Dietary PUFAs.
Advances in Nutrition, 2015 Oxylipins formed from polyunsaturated fatty acids (PUFAs) are the main mediators of PUFA effects in the body. They are formed via cyclooxygenase, lipoxygenase, and cytochrome P450 pathways, resulting in the formation of prostaglandins, thromboxanes, mono-
M. Gabbs +4 more
semanticscholar +1 more source
Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis [PDF]
Mediators of Inflammation, 2016 Sepsis, frequently caused by infection of bacteria, is considered as an uncontrollable systematic inflammation response syndrome (SIRS). Maresin 1 (Mar1) is a new proresolving mediator with potent anti-inflammatory effect in several animal models. However, its effect in sepsis is still not investigated.
Ruidong Li +8 more
openaire +3 more sources
Health Science Reports, Volume 9, Issue 8, August 2026.ABSTRACT Background and Aims Atherosclerosis is a lipid‐induced chronic inflammatory cardiovascular disorder denoted by the infiltration of immune cells and the agglomeration of lipids in the intima, the innermost layer, of the arteries of large and medium sizes.
Ramin Lotfi +4 more
wiley +1 more source
Differential Effects of Benralizumab and Mepolizumab on Pro‐Resolving Mediators
Allergy, EarlyView.
Jaime Bernaola +14 more
wiley +1 more source
Macrophage: Biological Functions, Diseases, and Therapeutic Targets
MedComm, Volume 7, Issue 8, August 2026.Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun +4 more
wiley +1 more source
Resolvins and Protectins in Inflammation-Resolution
Chemical Reviews, 2011 The critical role of inflammatory processes in health and disease has long been recognized,1 yet the detailed molecular mechanisms and biological events that regulate the progression and resolution of inflammation remain of interest.
C. Serhan, N. Petasis
semanticscholar +1 more source
Specialized Pro-Resolving Mediator Network: An Update on Production and Actions
Essays in Biochemistry, 2020 Today, persistent and uncontrolled inflammation is appreciated to play a pivotal role in many diseases, such as cardiovascular disease, neurodegenerative diseases, metabolic syndrome, and many other diseases of public health concern (e.g.
Chia Nan, C. Serhan
semanticscholar +1 more source
Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.An engineered EcN‐RvE1 probiotic platform enables sustained biosynthesis of the pro‐resolving mediator RvE1 via inducible COX2/5‐LOX expression. Oral administration achieves long‐term intestinal persistence and systemic anti‐inflammatory effects in murine models of acute inflammation and colitis, offering a promising oral therapeutic strategy for ...
Xiaoxiao Li +11 more
wiley +1 more source