Results 71 to 80 of about 3,018 (169)

Maresin 1 biosynthesis during platelet–neutrophil interactions is organ-protective [PDF]

Proceedings of the National Academy of Sciences, 2014
Significance Neutrophil accumulation is fundamental to acute inflammation. In response to tissue injury, circulating neutrophil–platelet aggregates (N-PAs) form for secondary capture. Counterregulation of acute inflammatory processes by specialized proresolving mediators is essential to mitigate collateral injury to healthy bystander tissue ...
Abdulnour, Raja-Elie, Dalli, Jesmond, Colby, Jennifer, Krishnamoorthy, Nandini, Timmons, Jack, Tan, Sook Hwa, Colas, Romain, Petasis, Nicos, Serhan, Charles, Levy, Bruce   +9 more
openaire   +4 more sources

Pro-Resolving Lipid Mediators in the Pathophysiology of Asthma

Medicina, 2019
Asthma is one of the most important medical and social problems of our time due to the prevalence and the complexity of its treatment. Chronic inflammation that is characteristic of asthma is accompanied by bronchial obstruction, which involves various ...
Oxana Kytikova, Tatyana Novgorodtseva, Yulia Denisenko, Marina Antonyuk, Tatyana Gvozdenko   +4 more
doaj   +1 more source

Roles, Actions, and Therapeutic Potential of Specialized Pro-resolving Lipid Mediators for the Treatment of Inflammation in Cystic Fibrosis

Frontiers in Pharmacology, 2019
Non-resolving inflammation is the main mechanism of morbidity and mortality among patients suffering from cystic fibrosis (CF), the most common life-threatening human genetic disease.
Antonio Recchiuti, Antonio Recchiuti, Domenico Mattoscio, Domenico Mattoscio, Elisa Isopi, Elisa Isopi   +5 more
doaj   +1 more source

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

Advanced Science, Volume 13, Issue 29, 22 May 2026.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu, Abudureyimujiang Aili, Zheng Kuang, Liting Cao, Zemin Li, Ying Shang, Yingying Ge, Tingting Hu, Yongchang Sun, Wuli Zhao, Rong Jin, Chun Chang   +11 more
wiley   +1 more source

Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis [PDF]

Mediators of Inflammation, 2016
Sepsis, frequently caused by infection of bacteria, is considered as an uncontrollable systematic inflammation response syndrome (SIRS). Maresin 1 (Mar1) is a new proresolving mediator with potent anti-inflammatory effect in several animal models. However, its effect in sepsis is still not investigated.
Ruidong Li, Yaxin Wang, Zhijun Ma, Muyuan Ma, Di Wang, Gengchen Xie, Yuping Yin, Peng Zhang, Kaixiong Tao   +8 more
openaire   +3 more sources

HEMOSTASIS AND LIPID PROFILE FEATURES IN THE NORTH

Атеросклероз, 2019
The reviews analyzed the research data of recent decades, as a result of which the features of the hemostatic system and lipid profile in the North were studied, which allows us to look at development under conditions of successful adaptation to adverse ...
A. A. Gromov, M. V. Kruchinina, V. N. Kruchinin   +2 more
doaj   +1 more source

Lipoxin A4 and Resolvin D1 Preserve Neural Inductive Capacity of Dental Pulp Stem Cells Cultured Under Inflammatory Conditions

Cell Biology International, Volume 50, Issue 5, May 2026.
ABSTRACT Human dental pulp stem cells (DPSCs) exhibit neurogenic differentiation potential; however, inflammatory conditions may impair this process. This study investigated the impact of tumor necrosis factor alpha (TNF‐α) on the neurodifferentiation potential of DPSCs and the modulatory role of the pro‐resolving lipid mediators lipoxin A4 (LXA4) and ...
Ana Paula Turrioni, Geovana Pires da Silva, Yan Xu, Alpdogan Kantarci, Hatice Hasturk, Ricardo A. Battaglino, Leslie R. Morse   +6 more
wiley   +1 more source

Maresin-1 impairs cutaneous wound healing response

ImmunoHorizons
Abstract Maresin-1 is a derivative of docosahexaenoic acid with strong anti-inflammatory action in various disease models. However, these effects may not always be beneficial. In instances like cutaneous diseases in which wound healing is important, inflammation is required.
Reiko Hara, Natsuko Saito-Sasaki, Yu Sawada   +2 more
openaire   +2 more sources

Can Inflammation-Resolution Provide Clues to Treat Patients According to Their Plaque Phenotype?

Frontiers in Pharmacology, 2019
Inflammation-resolution is an active process that is governed in part by specialized pro-resolving mediators (SPMs) such as lipoxins, resolvins, protectins, and maresins.
Gabrielle Fredman
doaj   +1 more source

The future of periodontology: Emerging technologies and conceptual shifts

Journal of Periodontology, Volume 97, Issue 5, Page 875-882, May 2026.
Abstract Periodontology is entering a transformative era driven by advances in diagnostics, therapeutics, and digital integration. Emerging technologies and conceptual shifts are currently reshaping the specialty, with a focus on predictive, preventive, and personalized care.
Michael S. Reddy
wiley   +1 more source