Results 41 to 50 of about 11,403 (227)

Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges

Advanced Science, EarlyView.
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen, Bao Chen, Wenhui Zhang, Guifang Sun, Yao Zhao, Jianpeng Zhang, Baofu Xu   +6 more
wiley   +1 more source

New Andrastin-Type Meroterpenoids from the Marine-Derived Fungus Penicillium sp.

Marine Drugs, 2021
Three new andrastin-type meroterpenoids penimeroterpenoids A–C (1–3) together with two known analogs (4 and 5) were isolated from the cultures of the marine-derived Penicillium species (sp.).
Jinwei Ren, Ruiyun Huo, Gaoran Liu, Ling Liu   +3 more
doaj   +1 more source

Bioactive Bianthraquinones and Meroterpenoids from a Marine-Derived Stemphylium sp. Fungus [PDF]

Marine Drugs, 2020
Three new bianthraquinones, alterporriol Z1–Z3 (1–3), along with three known compounds of the same structural class, were isolated from the culture broth of a marine-derived Stemphylium sp. fungus. Based upon the results of spectroscopic analyses and ECD measurements, the structures of new compounds were determined to be the 6-6′- (1 and 2) and 1-5 ...
Ji-Yeon Hwang, Sung Chul Park, Woong Sub Byun, Dong-Chan Oh, Sang Kook Lee, Ki-Bong Oh, Jongheon Shin   +6 more
openaire   +3 more sources

Evolutionary, Functional and Mechanistic Characterisation of Microbial Terpene Synthase‐Like Genes From Springtails

Angewandte Chemie International Edition, EarlyView.
A genome analysis revealed the presence of many bacterial‐type terpene synthases in springtails. Four enzymes from Sinella curviseta were functionally characterised, resulting in the isolation of several compounds including sinellene ether, the first diterpene ether identified from a terpene synthase that represents a novel skeleton.
Min Wang, Clement Schneider, Zarley Rebholz, Stefan Schulz, Kathy Darragh, Jeroen S. Dickschat   +5 more
wiley   +1 more source

Pretrichodermamides D–F from a Marine Algicolous Fungus Penicillium sp. KMM 4672

Marine Drugs, 2016
Three new epidithiodiketopiperazines pretrichodermamides D–F (1–3), together with the known N-methylpretrichodermamide B (4) and pretrichodermamide С (5), were isolated from the lipophilic extract of the marine algae-derived fungus Penicillium sp.
Anton N. Yurchenko, Olga F. Smetanina, Elena V. Ivanets, Anatoly I. Kalinovsky, Yuliya V. Khudyakova, Natalya N. Kirichuk, Roman S. Popov, Carsten Bokemeyer, Gunhild von Amsberg, Ekaterina A. Chingizova, Shamil Sh. Afiyatullov, Sergey A. Dyshlovoy   +11 more
doaj   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

New Metabolites from the Algal Associated Marine-derived Fungus

Natural Product Communications, 2013
The new oxepin-containing ( 1 ) and quinazolinone ( 2 ) alkaloids and new dihydrobenzofuran derivative ( 3 ) have been isolated from a marine strain of Aspergillus carneus KMM 4638.
Olesya I. Zhuravleva, Shamil Sh. Afiyatullov, Ekaterina A. Yurchenko, Vladimir A. Denisenko, Natalya N. Kirichuk, Pavel S. Dmitrenok   +5 more
doaj   +1 more source

Cytotoxic and Antimicrobial Compounds from the Marine-Derived Fungus, Penicillium Species [PDF]

Molecules, 2018
The organic extract of liquid cultures of the marine-derived Penicillium sp. was investigated. Fractionation of the extracts of the fungus led to the purification and identification of two new compounds, penicillatides A (1) and B (2), together with the previously reported cyclo(R-Pro–S-Phe) (3) and cyclo(R-Pro–R-Phe) (4). The structures of compounds 1–
Diaa Youssef, Abdulrahman Alahdal
openaire   +3 more sources

Biochemical Studies and Production Optimization of β‐Glucosidase From Microcystis aeruginosa CACIAM 03 Using Organic Waste

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Global warming and industrial pollutants pose significant threats to environmental sustainability. In response, enzymes have emerged as promising tools for mitigating pollution. Enzymatic hydrolysis is considered environmentally sustainable due to its biological nature.
Gustavo Marques Serra, Matheus Silva da Fonseca Diniz, Evonnildo Costa Gonçalves, Agenor Valadares Santos, Luciana Pereira Xavier   +4 more
wiley   +1 more source

New Polyketides from the Marine-Derived Fungus Letendraea Sp. 5XNZ4-2

Marine Drugs, 2019
Marine-derived fungi have been reported to have great potential to produce structurally unique metabolites. Our investigation on secondary metabolites from marine-derived fungi resulted in the isolation of seven new polyketides (phomopsiketones D−G
Yan Xu, Ruibao Huang, Hongwei Liu, Tingting Yan, Wanjing Ding, Yongjun Jiang, Pinmei Wang, Daoqiong Zheng, Jinzhong Xu   +8 more
doaj   +1 more source