Results 1 to 10 of about 42,850 (196)
New Antibacterial Secondary Metabolites from a Marine-Derived Talaromyces sp. Strain BTBU20213036
Antibiotics, 2022 New polyketide-derived oligophenalenone dimers, bacillisporins K and L (1 and 2) and xanthoradone dimer rugulosin D (3), together with four known compounds, bacillisporin B (4), macrosporusone D (5), rugulosin A and penicillide (6 and 7), were isolated ...
Fuhang Song +5 more
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Hydrobiology, 2023 Streptomyces sp. N11-50 was isolated from deep-sea water and found to produce diketopiperazine (DKP) compounds such as albonoursin and cyclo(Phe-Leu).
Hisayuki Komaki +2 more
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First Identification of Amphidinols from Mexican Strains and New Analogs
Toxins, 2023 The genus Amphidinium has been the subject of recent attention due to the production of polyketide metabolites. Some of these compounds have shown significant bioactivities and could be related to species interactions in the natural benthic ...
Lorena M. Durán-Riveroll +2 more
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Marine Drugs, 2023 Chemical epigenetic cultivation of the sponge-derived fungus Pestalotiopsis sp. SWMU-WZ04-1 contributed to the identification of twelve polyketide derivatives, including six new pestalotiopols E–J (1–6) and six known analogues (7–12).
Liyuan Jiang +7 more
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Frontiers in Plant Science, 2020 Extracellular vesicles (EVs) represent a system for the coordinated secretion of a variety of molecular cargo including proteins, lipids, nucleic acids, and metabolites.
Mark R. Bleackley +9 more
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Biosynthesis of Fungal Natural Products Involving Two Separate Pathway Crosstalk
Journal of Fungi, 2022 Fungal natural products (NPs) usually possess complicated structures, exhibit satisfactory bioactivities, and are an outstanding source of drug leads, such as the cholesterol-lowering drug lovastatin and the immunosuppressive drug mycophenolic acid.
Guangzhi Dai +3 more
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ClbR Is the Key Transcriptional Activator of Colibactin Gene Expression in
mSphere, 2020 Colibactin is a nonribosomal peptide/polyketide hybrid natural product expressed by different members of the Enterobacteriaceae which can be correlated with induction of DNA double-strand breaks and interference with cell cycle progression in eukaryotes.
Alexander Wallenstein +16 more
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eLife, 2020 Microorganisms produce numerous secondary metabolites (SMs) with various biological activities. Many of their encoding gene clusters are silent under standard laboratory conditions because for their activation they need the ecological context, such as ...
Maria Cristina Stroe +6 more
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The Toughest Material in the Plant Kingdom: An Update on Sporopollenin
Frontiers in Plant Science, 2021 The extreme chemical and physical recalcitrance of sporopollenin deems this biopolymer among the most resilient organic materials on Earth. As the primary material fortifying spore and pollen cell walls, sporopollenin is touted as a critical innovation ...
Etienne Grienenberger +1 more
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mSystems, 2023 Actinomycetes are prolific producers of industrially valuable and medically important compounds. Historically, the most efficient method of obtaining compounds has been bioactivity-guided isolation and characterization of drug-like molecules from ...
Peng Hou +5 more
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