Results 41 to 50 of about 39,295 (245)
Antibiotics, 2019 We previously identified the aur1 gene cluster in Streptomyces lavendulae subsp. lavendulae CCM 3239 (formerly Streptomyces aureofaciens CCM 3239), which is responsible for the production of the angucycline-like antibiotic auricin (1).
Maria Matulova +13 more
doaj +1 more source
Two New Polyketide Metabolites Isolated from Paraconiothyrium brasiliense [PDF]
, 2017 Two new polyketide metabolites, named ethyl 8-hydroxy-9-oxo-9H-xanthene-1-carboxylate (1) and 1,8-dihydroxy-2-(1-hydroxyethyl)anthracene-9,10-dione (2), along with six known compounds, were isolated from the fungus Paraconiothyrium brasiliense.
Yang, T +6 more
core +1 more source
Promiscuity‐Guided Enzyme Evolution via Substrate Multiplexed Screening
Angewandte Chemie, EarlyView.Through historical context and recent examples, this Minireview summarizes the strengths, limitations, and practical considerations for the implementation of substrate multiplexed screening (SUMS) in enzyme evolution. ABSTRACT An enzyme's ability to react with diverse substrates while maintaining high yield and selectivity, termed “substrate ...
Holly A. Weilbaker +3 more
wiley +2 more sources
Polyketides from a Marine-Derived Fungus Xylariaceae sp.
Marine Drugs, 2013 Eighteen polyketides (1–18) including six citrinin derivatives, two phenol derivatives, one cyclopentenone, two naphthol derivatives, and seven tetralone derivatives were isolated from the culture broth of a marine-derived fungal strain Xylariaceae sp ...
Shu-Hua Qi +4 more
doaj +1 more source
Polymorphism of the Polyketide Synthase Gene phlD in Biocontrol Fluorescent Pseudomonads Producing 2,4-Diacetylphloroglucinol and Comparison of PhlD with Plant Polyketide Synthases [PDF]
, 2001 Many biocontrol fluorescent pseudomonads can protect plants from soilborne fungal pathogens through production of the antifungal secondary metabolite 2,4-diacetylphloroglucinol (Phl). One of the phl biosynthetic genes, phlD, encodes a polyketide synthase
Ramette, Alban Nicolas +2 more
core +1 more source
Angewandte Chemie, EarlyView.The fischerazoles, unusual cyanobacterial chlorinated lipopeptides are reported. During their biosynthesis, a linear fatty acyl‐acyl carrier protein (ACP) precursor is rearranged through the action of the S‐adenosyl‐methionine (SAM)‐dependent methyltransferase FshF, to generate a pendant vinyl group.
Sandra A. C. Figueiredo +8 more
wiley +2 more sources
Marine Drugs, 2020 A new pentaketide derivative, penilactonol A (1), and two new hydroxyphenylacetic acid derivatives, (2’R)-stachyline B (2) and (2’R)-westerdijkin A (3), together with five known metabolites, bisabolane-type sesquiterpenoids 4–6 and meroterpenoids 7 and 8,
Lin-Lin Jiang +9 more
doaj +1 more source
Microorganisms, 2023 Biofouling is the assemblage of undesirable biological materials and macro-organisms (barnacles, mussels, etc.) on submerged surfaces, which has unfavorable impacts on the economy and maritime environments.
Radwa N. Morgan +3 more
doaj +1 more source
Cellular compartmentalization of secondary metabolism
Frontiers in Microbiology, 2015 Fungal secondary metabolism is often considered apart from the essential housekeeping functions of the cell. However, there are clear links between fundamental cellular metabolism and the biochemical pathways leading to secondary metabolite synthesis ...
H. Corby eKistler, Karen eBroz
doaj +1 more source
Detection of Mycolactone A/B in Mycobacterium ulcerans-Infected Human Tissue. [PDF]
, 2010 BACKGROUND: Mycobacterium ulcerans disease (Buruli ulcer) is a neglected tropical disease common amongst children in rural West Africa. Animal experiments have shown that tissue destruction is caused by a toxin called mycolactone.
Engy A. Mahrous +32 more
core +1 more source