Results 61 to 70 of about 39,295 (245)

Polyketide Synthase and Nonribosomal Peptide Synthetase Gene Clusters in Type Strains of the Genus Phytohabitans

open access: yesLife, 2020
(1) Background: Phytohabitans is a recently established genus belonging to rare actinomycetes. It has been unclear if its members have the capacity to synthesize diverse secondary metabolites.
Hisayuki Komaki, Tomohiko Tamura
doaj   +1 more source

Effect of the Marine Polyketide Plocabulin on Tumor Progression

open access: yesMarine Drugs, 2022
Marine sponges represent one of the richest sources of natural marine compounds with anticancer potential. Plocabulin (PM060184), a polyketide originally isolated from the sponge Lithoplocamia lithistoides, elicits its main anticancer properties binding ...
Eleonora Turrini   +2 more
doaj   +1 more source

Resistant Peanut Genotype Reprograms Rhizosphere Metabolism to Enhance Bacterial Wilt Suppression

open access: yesAdvanced Science, EarlyView.
The resistant peanut genotype selectively recruits beneficial bacteria, which coincides with the activation of salicylic acid (SA)‐dependent systemic acquired resistance (SAR) against Ralstonia solanacearum. Keystone rhizosphere metabolites are positively correlated with both beneficial microbiome assembly and SAR gene expression.
Rui Ren   +20 more
wiley   +1 more source

Cloning and Molecular Characterization of the phlD Gene Involved in the Biosynthesis of “Phloroglucinol”, a Compound with Antibiotic Properties from Plant Growth Promoting Bacteria Pseudomonas spp.

open access: yesAntibiotics, 2023
phlD is a novel kind of polyketide synthase involved in the biosynthesis of non-volatile metabolite phloroglucinol by iteratively condensing and cyclizing three molecules of malonyl-CoA as substrate. Phloroglucinol or 2,4-diacetylphloroglucinol (DAPG) is
Payal Gupta   +5 more
doaj   +1 more source

Bioinspired iterative synthesis of polyketides [PDF]

open access: yesFrontiers in Chemistry, 2015
Diverse array of biopolymers and second metabolites (particularly polyketide natural products) has been manufactured in nature through an enzymatic iterative assembly of simple building blocks. Inspired by this strategy, molecules with inherent modularity can be efficiently synthesized by repeated succession of similar reaction sequences.
Zheng, Kuan, Xie, Changmin, Hong, Ran
openaire   +3 more sources

Novel Mechanism for Priming Aromatic Polyketide Synthases [PDF]

open access: yes, 2004
In this issue of Chemistry & Biology, a novel priming mechanism is proposed for aromatic polyketide biosynthesis, with an iterative type I polyketide synthase generating a starter unit primed for a type II polyketide synthase [6].
Salas, José A
core   +1 more source

The Polyketides with Antimicrobial Activities from a Mangrove Endophytic Fungus Trichoderma lentiforme ML-P8-2

open access: yesMarine Drugs, 2023
Five new polyketides, including two chromones (1–2), two phenyl derivatives (4–5), and a tandyukusin derivative (6), along with five known polyketides (3 and 7–10) were isolated from mangrove endophytic fungus Trichoderma lentiforme ML-P8-2.
Yihao Yin   +6 more
doaj   +1 more source

Polyketide stereotetrads in natural products [PDF]

open access: yesChemical Society Reviews, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Koskinen, Ari M.P., Karisalmi, Kaisa
openaire   +3 more sources

Towards preparative in vitro enzymatic synthesis of new polyketide metabolites [PDF]

open access: yes, 2013
textModular polyketide synthases (PKSs) are the largest enzymes known to man and are responsible for synthesizing some of the most important human medicines.
Hughes, Amanda Jane
core  

Characterization of the Red Biochromes Produced by the Endophytic Fungus Monascus purpureus CPEF02 with Antimicrobial and Antioxidant Activities

open access: yesFermentation, 2023
Food acceptability and appeal are significantly influenced by colour. Harmful effects associated with synthetic colorants are well established, and research is currently focused on developing natural, synthetic chemical-free substitutes from fungal ...
Mehak Kaur   +5 more
doaj   +1 more source

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